Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 12895 件
4C8L
DownloadVisualize
BU of 4c8l by Molmil
Binary complex of the large fragment of DNA polymerase I from Thermus Aquaticus with the artificial base pair dNaM-d5SICS at the postinsertion site (sequence context 1)
分子名称: 5'-D(*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*LHOP)-3', 5'-D(*AP*GP*BMNP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP)-3', DNA POLYMERASE I, ...
著者Betz, K, Malyshev, D.A, Lavergne, T, Welte, W, Diederichs, K, Romesberg, F.E, Marx, A.
登録日2013-10-01
公開日2013-12-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Insights Into DNA Replication without Hydrogen Bonds.
J.Am.Chem.Soc., 135, 2013
5US3
DownloadVisualize
BU of 5us3 by Molmil
Heterogeneous-backbone Foldamer Mimic of the Sp1-3 Zinc Finger
分子名称: Heterogeneous-Backbone Variant of the Sp1-3 Zinc Finger: N-Me-Ala3, N-Me-Arg10, beta-3-Asp15, ...
著者George, K.L, Horne, W.S.
登録日2017-02-13
公開日2017-05-31
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Heterogeneous-Backbone Foldamer Mimics of Zinc Finger Tertiary Structure.
J. Am. Chem. Soc., 139, 2017
3S4B
DownloadVisualize
BU of 3s4b by Molmil
Cellobiose phosphorylase from Cellulomonas uda in complex with glucose
分子名称: Cellobiose phosphorylase, alpha-D-glucopyranose
著者Van Hoorebeke, A, Stout, J, Soetaert, W, Van Beeumen, J, Desmet, T, Savvides, S.
登録日2011-05-19
公開日2012-06-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cellobiose phosphorylase: reconstructing the structural itinerary along the catalytic pathway
To be Published
4CD0
DownloadVisualize
BU of 4cd0 by Molmil
Structure of L1196M Mutant Human Anaplastic Lymphoma Kinase in Complex with 2-(5-(6-amino-5-((R)-1-(5-fluoro-2-(2H-1,2,3-triazol-2- yl)phenyl)ethoxy)pyridin-3-yl)-4-methylthiazol-2-yl)propane-1,2-diol
分子名称: (2R)-2-[5-(6-amino-5-{(1R)-1-[2-(1,3-dihydro-2H-1,2,3-triazol-2-yl)-5-fluorophenyl]ethoxy}pyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]propane-1,2-diol, ALK TYROSINE KINASE RECEPTOR
著者McTigue, M, Deng, Y, Liu, W, Brooun, A, Stewart, A.
登録日2013-10-29
公開日2014-01-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献The Design of Potent and Selective Inhibitors to Overcome Clinical Alk Mutations Resistant to Crizotinib.
J.Med.Chem., 57, 2014
3S7K
DownloadVisualize
BU of 3s7k by Molmil
Structure of thrombin mutant Y225P in the E form
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, POTASSIUM ION, Prothrombin
著者Niu, W, Chen, Z, Gandhi, P, Vogt, A, Pozzi, N, Pele, L.A, Zapata, F, Di Cera, E.
登録日2011-05-26
公開日2011-07-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like Protease.
Biochemistry, 50, 2011
4NSY
DownloadVisualize
BU of 4nsy by Molmil
Wild-type lysobacter enzymogenes lysc endoproteinase covalently inhibited by TLCK
分子名称: CALCIUM ION, CHLORIDE ION, Lysyl endopeptidase, ...
著者Asztalos, P, Muller, A, Holke, W, Sobek, H, Rudolph, M.G.
登録日2013-11-29
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Atomic resolution structure of a lysine-specific endoproteinase from Lysobacter enzymogenes suggests a hydroxyl group bound to the oxyanion hole.
Acta Crystallogr.,Sect.D, 70, 2014
4O0Z
DownloadVisualize
BU of 4o0z by Molmil
Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase
分子名称: N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}indolizine-6-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION
著者Oh, A, Wang, W.
登録日2013-12-14
公開日2014-06-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.049 Å)
主引用文献Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase.
Chembiochem, 15, 2014
3SJK
DownloadVisualize
BU of 3sjk by Molmil
Crystal structure of the C147A mutant 3C from enterovirus 71
分子名称: 3C protease, KPVLRTATVQGPSLDF peptide
著者Lu, G, Qi, J, Chen, Z, Xu, X, Gao, F, Lin, D, Qian, W, Liu, H, Jiang, H, Yan, J, Gao, G.F.
登録日2011-06-21
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
4NWF
DownloadVisualize
BU of 4nwf by Molmil
Crystal structure of the tyrosine phosphatase SHP-2 with N308D mutation
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 11
著者Qiu, W, Lin, A, Hutchinson, A, Romanov, V, Ruzanov, M, Thompson, C, Lam, K, Kisselman, G, Battalie, K, Chirgadze, N.Y.
登録日2013-12-06
公開日2014-12-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the tyrosine phosphatase SHP-2 with N308D mutation
To be Published
4JR5
DownloadVisualize
BU of 4jr5 by Molmil
Structure-based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
分子名称: 1,2-ETHANEDIOL, 1-[4-(piperidin-1-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)thiourea, Nicotinamide phosphoribosyltransferase, ...
著者Zheng, X, Bauer, P, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Han, B, Ho, Y, Kley, N, Lin, J, Reynolds, D.J, Sharma, G, Smith, C.C, Wang, Z, Dragovich, P.S, Oh, A, Wang, W, Zak, M, Gunzner-Toste, J, Zhao, G, Yuen, P, Bair, K.W.
登録日2013-03-21
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.906 Å)
主引用文献Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (nampt) inhibitors.
J.Med.Chem., 56, 2013
4JU0
DownloadVisualize
BU of 4ju0 by Molmil
Crystal structure of 2009 pandemic influenza virus hemagglutinin mutant D225E complexed with human receptor analogue LSTc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Zhang, W, Shi, Y, Qi, J, Gao, F, Li, Q, Fan, Z, Yan, J, Gao, G.F.
登録日2013-03-24
公開日2013-05-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.908 Å)
主引用文献Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
4NFE
DownloadVisualize
BU of 4nfe by Molmil
Human kallikrein-related peptidase 2 in complex with benzamidine
分子名称: BENZAMIDINE, Kallikrein-2, SULFATE ION
著者Skala, W, Brandstetter, H, Magdolen, V, Goettig, P.
登録日2013-10-31
公開日2014-10-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity
J.Biol.Chem., 289, 2014
4ETB
DownloadVisualize
BU of 4etb by Molmil
lysozyme, room temperature, 200 kGy dose
分子名称: CHLORIDE ION, Lysozyme C
著者Boutet, S, Lomb, L, Williams, G, Barends, T, Aquila, A, Doak, R.B, Weierstall, U, DePonte, D, Steinbrener, J, Shoeman, R, Messerschmidt, M, Barty, A, White, T, Kassemeyer, S, Kirian, R, Seibert, M, Montanez, P, Kenney, C, Herbst, R, Hart, P, Pines, J, Haller, G, Gruner, S, Philllip, H, Tate, M, Hromalik, M, Koerner, L, van Bakel, N, Morse, J, Ghonsalves, W, Arnlund, D, Bogan, M, Calemann, C, Fromme, R, Hampton, C, Hunter, M, Johansson, L, Katona, G, Kupitz, C, Liang, M, Martin, A, Nass, K, Redecke, L, Stellato, F, Timneanu, N, Wang, D, Zatsepin, N, Schafer, D, Defever, K, Neutze, R, Fromme, P, Spence, J, Chapman, H, Schlichting, I.
登録日2012-04-24
公開日2012-06-13
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.908 Å)
主引用文献High-resolution protein structure determination by serial femtosecond crystallography.
Science, 337, 2012
4J9N
DownloadVisualize
BU of 4j9n by Molmil
Human DNA polymerase eta-DNA ternary complex: misincorporation G opposite T after a G at the primer 3' end (GA/G)
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA, DNA polymerase eta, ...
著者Zhao, Y, Gregory, M, Biertumpfel, C, Hua, Y, Hanaoka, F, Yang, W.
登録日2013-02-16
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.956 Å)
主引用文献Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JBM
DownloadVisualize
BU of 4jbm by Molmil
Structure of murine DNA binding protein bound with ds DNA
分子名称: DNA (5'-D(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), Interferon-inducible protein AIM2
著者Ru, H, Ni, X, Crowley, C, Zhao, L, Ding, W, Hung, L.-W, Shaw, N, Cheng, G, Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.218 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
3U7X
DownloadVisualize
BU of 3u7x by Molmil
Crystal structure of the human eIF4E-4EBP1 peptide complex without cap
分子名称: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1, SULFATE ION, ...
著者Siddiqui, N, Tempel, W, Nedyalkova, L, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Borden, K.L.B, Park, H, Structural Genomics Consortium (SGC)
登録日2011-10-14
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4E.
J.Mol.Biol., 415, 2012
4NM6
DownloadVisualize
BU of 4nm6 by Molmil
Crystal structure of TET2-DNA complex
分子名称: 5'-D(*AP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*T)-3', FE (II) ION, Methylcytosine dioxygenase TET2, ...
著者Hu, L, Li, Z, Cheng, J, Rao, Q, Gong, W, Liu, M, Wang, P, Xu, Y.
登録日2013-11-14
公開日2013-12-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.026 Å)
主引用文献Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation.
Cell(Cambridge,Mass.), 155, 2013
4J81
DownloadVisualize
BU of 4j81 by Molmil
Crystal structure of beta'-COP/Insig-1 complex
分子名称: Coatomer subunit beta', Insulin-induced gene 1 protein
著者Ma, W, Goldberg, J.
登録日2013-02-14
公開日2013-03-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.745 Å)
主引用文献Rules for the recognition of dilysine retrieval motifs by coatomer.
Embo J., 32, 2013
3U1L
DownloadVisualize
BU of 3u1l by Molmil
Structure of the mRNA splicing complex component Cwc2
分子名称: Pre-mRNA-splicing factor CWC2, ZINC ION
著者Lu, P, Lu, G, Yan, C, Wang, L, Li, W, Yin, P.
登録日2011-09-30
公開日2011-11-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structure of the mRNA splicing complex component Cwc2: insights into RNA recognition
Biochem.J., 441, 2012
4ESJ
DownloadVisualize
BU of 4esj by Molmil
RESTRICTION ENDONUCLEASE DpnI IN COMPLEX WITH TARGET DNA
分子名称: AZIDE ION, DNA (5'-D(*CP*TP*GP*GP*(6MA)P*TP*CP*CP*AP*G)-3'), GLYCEROL, ...
著者Siwek, W, Czapinska, H, Bochtler, M, Bujnicki, J.M, Skowronek, K.
登録日2012-04-23
公開日2012-06-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI.
Nucleic Acids Res., 40, 2012
4ETE
DownloadVisualize
BU of 4ete by Molmil
Lysozyme, room-temperature, rotating anode, 0.0021 MGy
分子名称: CHLORIDE ION, Lysozyme C
著者Boutet, S, Lomb, L, Williams, G, Barends, T, Aquila, A, Doak, R.B, Weierstall, U, DePonte, D, Steinbrener, J, Shoeman, R, Messerschmidt, M, Barty, A, White, T, Kassemeyer, S, Kirian, R, Seibert, M, Montanez, P, Kenney, C, Herbst, R, Hart, P, Pines, J, Haller, G, Gruner, S, Philllip, H, Tate, M, Hromalik, M, Koerner, L, van Bakel, N, Morse, J, Ghonsalves, W, Arnlund, D, Bogan, M, Calemann, C, Fromme, R, Hampton, C, Hunter, M, Johansson, L, Katona, G, Kupitz, C, Liang, M, Martin, A, Nass, K, Redecke, L, Stellato, F, Timneanu, N, Wang, D, Zatsepin, N, Schafer, D, Defever, K, Neutze, R, Fromme, P, Spence, J, Chapman, H, Schlichting, I.
登録日2012-04-24
公開日2012-06-13
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.905 Å)
主引用文献High-resolution protein structure determination by serial femtosecond crystallography.
Science, 337, 2012
3TI9
DownloadVisualize
BU of 3ti9 by Molmil
Crystal structure of the basic protease BprB from the ovine footrot pathogen, Dichelobacter nodosus
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Wong, W, Whisstock, J.C, Porter, C.J.
登録日2011-08-20
公開日2011-10-19
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献S1 Pocket of a Bacterially Derived Subtilisin-like Protease Underpins Effective Tissue Destruction.
J.Biol.Chem., 286, 2011
4EUY
DownloadVisualize
BU of 4euy by Molmil
Crystal structure of thioredoxin-like protein BCE_0499 from Bacillus cereus ATCC 10987
分子名称: Uncharacterized protein
著者Shabalin, I.G, Kagan, O, Chruszcz, M, Grabowski, M, Savchenko, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2012-04-25
公開日2012-05-16
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of thioredoxin-like protein BCE_0499 from Bacillus cereus
To be Published
4JBZ
DownloadVisualize
BU of 4jbz by Molmil
Structure of Mcm10 coiled-coil region
分子名称: MALTOSE-BINDING PERIPLASMIC PROTEIN FUSED WITH XENOPUS LAEVIS MCM10 COILED-COIL REGION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Du, W, Adhikary, S, Eichman, B.F.
登録日2013-02-20
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mcm10 self-association is mediated by an N-terminal coiled-coil domain.
Plos One, 8, 2013
4JFR
DownloadVisualize
BU of 4jfr by Molmil
Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with carbamoyl phosphate
分子名称: CHLORIDE ION, MAGNESIUM ION, Ornithine carbamoyltransferase, ...
著者Shabalin, I.G, Winsor, J, Grimshaw, S, Osinski, T, Bajor, J, Chordia, M.D, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-02-28
公開日2013-03-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis
to be published

222415

件を2024-07-10に公開中

PDB statisticsPDBj update infoContact PDBjnumon