4C8L

Binary complex of the large fragment of DNA polymerase I from Thermus Aquaticus with the artificial base pair dNaM-d5SICS at the postinsertion site (sequence context 1)

Summary for 4C8L

• Entry DOI: 10.2210/pdb4c8l/pdb
• Related: 4C8J 4C8K 4C8M 4C8N 4C8O
• Descriptor: DNA POLYMERASE I, THERMOSTABLE, 5'-D(*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*LHOP)-3', 5'-D(*AP*GP*BMNP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP)-3', ... (7 entities in total)
• Functional Keywords: transferase-dna complex, dna polymerase, unnatural base pair, artificial base pair, klentaq, transferase/dna
• Biological source: THERMUS AQUATICUS; More
• Total number of polymer chains: 3
• Total formula weight: 69254.30

Authors

Betz, K.,Malyshev, D.A.,Lavergne, T.,Welte, W.,Diederichs, K.,Romesberg, F.E.,Marx, A. (deposition date: 2013-10-01, release date: 2013-12-11, Last modification date: 2023-12-20)

• Primary citation: Betz, K.,Malyshev, D.A.,Lavergne, T.,Welte, W.,Diederichs, K.,Romesberg, F.E.,Marx, A.; Structural Insights Into DNA Replication without Hydrogen Bonds.; J.Am.Chem.Soc., 135:18637-, 2013; PubMed: 24283923; DOI: 10.1021/JA409609J

Experimental method

X-RAY DIFFRACTION (1.7 Å)