4WI6
| Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation N434A | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | 著者 | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | 登録日 | 2014-09-25 | 公開日 | 2015-09-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
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7FIT
| Crystal structure of Wolbachia cytoplasmic incompatibility factor CidA from wMel | 分子名称: | bacteria factor 1 | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-08-01 | 公開日 | 2022-04-06 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue. Nat Commun, 13, 2022
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3IEZ
| Crystal structure of the RasGAP C-terminal (RGC) domain of IQGAP2 | 分子名称: | Ras GTPase-activating-like protein IQGAP2, UNKNOWN ATOM OR ION | 著者 | Nedyalkova, L, Tempel, W, Tong, Y, Zhong, N, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2009-07-23 | 公開日 | 2009-11-03 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of the RasGAP C-terminal (RGC) domain
of IQGAP2 To be Published
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2V8F
| Mouse Profilin IIa in complex with a double repeat from the FH1 domain of mDia1 | 分子名称: | GLYCEROL, ISOPROPYL ALCOHOL, PROFILIN-2, ... | 著者 | Kursula, P, Kursula, I, Downer, J, Witke, W, Wilmanns, M. | 登録日 | 2007-08-07 | 公開日 | 2007-12-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp. J.Mol.Biol., 375, 2008
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2V13
| Crystal Structure of Renin with Inhibitor 7 | 分子名称: | N-[(2R,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE, RENIN | 著者 | Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G. | 登録日 | 2007-05-21 | 公開日 | 2008-07-08 | 最終更新日 | 2019-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin Chem.Biol., 7, 2000
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1W0C
| Inhibition of Leishmania major pteridine reductase (PTR1) by 2,4,6-triaminoquinazoline; structure of the NADP ternary complex. | 分子名称: | 2,4,6-TRIAMINOQUINAZOLINE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE | 著者 | Mcluskey, K, Gibellini, F, Carvalho, P, Avery, M, Hunter, W. | 登録日 | 2004-06-02 | 公開日 | 2004-09-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Inhibition of Leishmania Major Pteridine Reductase by 2,4,6-Triaminoquinazoline: Structure of the Nadph Ternary Complex Acta Crystallogr.,Sect.D, 60, 2004
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3IP2
| Crystal structure of red fluorescent protein Neptune at pH 7.0 | 分子名称: | Neptune red fluorescent protein | 著者 | Lin, M.Z, McKeown, M.R, Ng, H.L, Aguilera, T.A, Shaner, N.C, Ma, W, Adams, S.R, Campbell, R.E, Alber, T, Tsien, R.Y. | 登録日 | 2009-08-15 | 公開日 | 2009-12-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Autofluorescent proteins with excitation in the optical window for intravital imaging in mammals. Chem.Biol., 16, 2009
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1W77
| 2C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD) from Arabidopsis thaliana | 分子名称: | 2C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CADMIUM ION, COPPER (II) ION, ... | 著者 | Gabrielsen, M, Kaiser, J, Rohdich, F, Eisenreich, W, Bacher, A, Bond, C.S, Hunter, W.N. | 登録日 | 2004-08-30 | 公開日 | 2006-02-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Crystal Structure of a Plant 2C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase Exhibits a Distinct Quaternary Structure Compared to Bacterial Homologues and a Possible Role in Feedback Regulation for Cytidine Monophosphate. FEBS J., 273, 2006
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1VEV
| Crystal structure of peptide deformylase from Leptospira Interrogans (LiPDF) at pH6.5 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FORMIC ACID, Peptide deformylase, ... | 著者 | Zhou, Z, Song, X, Li, Y, Gong, W. | 登録日 | 2004-04-06 | 公開日 | 2005-08-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift J.Biol.Chem., 280, 2005
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2VDF
| Structure of the OpcA adhesion from Neisseria meningitidis determined by crystallization from the cubic mesophase | 分子名称: | N-OCTANE, OUTER MEMBRANE PROTEIN, SULFATE ION | 著者 | Cherezov, V, Liu, W, Derrick, J.P, Luan, B, Aksimentiev, A, Katritch, V, Caffrey, M. | 登録日 | 2007-10-05 | 公開日 | 2007-10-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin. Proteins, 71, 2008
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3HTP
| the hemagglutinin structure of an avian H1N1 influenza A virus in complex with LSTa | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | 著者 | Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y. | 登録日 | 2009-06-12 | 公開日 | 2009-08-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | The hemagglutinin structure of an avian H1N1 influenza A virus Virology, 392, 2009
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2VG3
| Rv2361 with citronellyl pyrophosphate | 分子名称: | CHLORIDE ION, GERANYL DIPHOSPHATE, GLYCEROL, ... | 著者 | Naismith, J.H, Wang, W, Dong, C. | 登録日 | 2007-11-08 | 公開日 | 2008-05-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The structural basis of chain length control in Rv1086. J. Mol. Biol., 381, 2008
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2V11
| Crystal Structure of Renin with Inhibitor 6 | 分子名称: | (2S,4S,5R,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL 1-BENZYL-1H-INDOLE-3-CARBOXYLATE, RENIN | 著者 | Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G. | 登録日 | 2007-05-21 | 公開日 | 2007-07-03 | 最終更新日 | 2019-04-03 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin Chem.Biol., 7, 2000
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3HVL
| Tethered PXR-LBD/SRC-1p complexed with SR-12813 | 分子名称: | Pregnane X receptor, Linker, Steroid receptor coactivator 1, ... | 著者 | Lesburg, C.A, Wang, W, Prosise, W.W, Chen, J, Taremi, S.S, Le, H.V, Madison, V, Cui, X, Thomas, A, Cheng, K.C. | 登録日 | 2009-06-16 | 公開日 | 2009-08-04 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability Protein Eng.Des.Sel., 21, 2008
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7ESH
| Crystal structure of amylosucrase from Calidithermus timidus | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, amylosucrase | 著者 | Tian, Y, Hou, X, Ni, D, Xu, W, Guang, C, Zhang, W, Rao, Y, Mu, W. | 登録日 | 2021-05-10 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structure-based interface engineering methodology in designing a thermostable amylose-forming transglucosylase J.Biol.Chem., 298, 2022
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2V6V
| The structure of the Bem1p PX domain | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BUD EMERGENCE PROTEIN 1 | 著者 | Stahelin, R.V, Karathanassis, D, Murray, D, Williams, R.L, Cho, W. | 登録日 | 2007-07-21 | 公開日 | 2007-07-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and Membrane Binding Analysis of the Phox Homology Domain of Bem1P: Basis of Phosphatidylinositol 4-Phosphate Specificity. J.Biol.Chem., 282, 2007
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3HXD
| Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 9) | 分子名称: | CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ... | 著者 | Guo, Z, Alexandrov, K, Waldmann, H, Goody, R.S, Blankenfeldt, W. | 登録日 | 2009-06-20 | 公開日 | 2009-09-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Design, synthesis, and characterization of Peptide-based rab geranylgeranyl transferase inhibitors J.Med.Chem., 52, 2009
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7BDV
| Structure of Can2 from Sulfobacillus thermosulfidooxidans in complex with cyclic tetra-adenylate (cA4) | 分子名称: | Can2, Cyclic tetraadenosine monophosphate (cA4) | 著者 | McQuarrie, S, McMahon, S.A, Gloster, T.M, White, M.F, Graham, S, Zhu, W, Gruschow, S. | 登録日 | 2020-12-22 | 公開日 | 2021-03-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence. Nucleic Acids Res., 49, 2021
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3HZJ
| Crystal structure of the RabGAP domain of the RABGAP1L protein | 分子名称: | RAB GTPase-activating protein 1-like, UNKNOWN ATOM OR ION | 著者 | Nedyalkova, L, Tempel, W, Tong, Y, Zhong, N, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2009-06-23 | 公開日 | 2009-07-14 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the RabGAP domain of the RABGAP1L protein To be Published
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3I07
| Crystal structure of a putative organic hydroperoxide resistance protein from Vibrio cholerae O1 biovar eltor str. N16961 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Organic hydroperoxide resistance protein | 著者 | Nocek, B, Maltseva, N, Kwon, K, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-06-24 | 公開日 | 2009-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | High resolution structural studies of the organic hydroperoxide
resistance protein from Vibrio cholerae O1 biovar eltor str. N16961 To be Published
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4YS5
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7TLL
| Structure of SARS-CoV-2 Mpro Omicron P132H in complex with Nirmatrelvir (PF-07321332) | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | 著者 | Greasley, S.E, Ferre, R.A, Plotnikova, O, Liu, W, Stewart, A.E. | 登録日 | 2022-01-18 | 公開日 | 2022-01-26 | 最終更新日 | 2022-06-15 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Structural basis for the in vitro efficacy of nirmatrelvir against SARS-CoV-2 variants. J.Biol.Chem., 298, 2022
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4YAY
| XFEL structure of human Angiotensin Receptor | 分子名称: | 5,7-diethyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-3,4-dihydro-1,6-naphthyridin-2(1H)-one, Soluble cytochrome b562,Type-1 angiotensin II receptor | 著者 | Zhang, H, Unal, H, Gati, C, Han, G.W, Zatsepin, N.A, James, D, Wang, D, Nelson, G, Weierstall, U, Messerschmidt, M, Williams, G.J, Boutet, S, Yefanov, O.M, White, T.A, Liu, W, Ishchenko, A, Tirupula, K.C, Desnoyer, R, Sawaya, M.C, Xu, Q, Coe, J, Cornrad, C.E, Fromme, P, Stevens, R.C, Katritch, V, Karnik, S.S, Cherezov, V, GPCR Network (GPCR) | 登録日 | 2015-02-18 | 公開日 | 2015-04-22 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of the Angiotensin receptor revealed by serial femtosecond crystallography. Cell, 161, 2015
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2V4E
| A non-cytotoxic DsRed variant for whole-cell labeling | 分子名称: | RED FLUORESCENT PROTEIN DRFP583 | 著者 | Strack, R.L, Strongin, D.E, Bhattacharyya, D, Tao, W, Berman, A, Broxmeyer, H.E, Keenan, R.J, Glick, B.S. | 登録日 | 2008-09-20 | 公開日 | 2008-11-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A Noncytotoxic Dsred Variant for Whole-Cell Labeling. Nat.Methods, 5, 2008
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1VEY
| Crystal Structure of Peptide Deformylase from Leptospira Interrogans (LiPDF) at pH7.0 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Peptide deformylase, ZINC ION | 著者 | Zhou, Z, Song, X, Li, Y, Gong, W. | 登録日 | 2004-04-06 | 公開日 | 2005-08-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift J.Biol.Chem., 280, 2005
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