4O9H
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![BU of 4o9h by Molmil](/molmil-images/mine/4o9h) | Structure of Interleukin-6 in complex with a Camelid Fab fragment | Descriptor: | Heavy Chain of the Camelid Fab fragment 61H7, Interleukin-6, Light Chain of the Camelid Fab fragment 61H7 | Authors: | Klarenbeek, A, Blanchetot, C, Schragel, G, Sadi, A.S, Ongenae, N, Hemrika, W, Wijdenes, J, Spinelli, S, Desmyter, A, Cambillau, C, Hultberg, A, Kretz-rommel, A, Dreier, T, De haard, H.J.W, Roovers, R.C. | Deposit date: | 2014-01-02 | Release date: | 2015-04-15 | Last modified: | 2015-04-29 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Combining residues of naturally-occurring Camelid somatic affinity variants yields ultra-potent human therapeutic IL-6 antibodies To be Published
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3JAF
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![BU of 3jaf by Molmil](/molmil-images/mine/3jaf) | Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine/ivermectin-bound state | Descriptor: | (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1 | Authors: | Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E. | Deposit date: | 2015-06-08 | Release date: | 2015-09-09 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.801 Å) | Cite: | Glycine receptor mechanism elucidated by electron cryo-microscopy. Nature, 526, 2015
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8UZE
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![BU of 8uze by Molmil](/molmil-images/mine/8uze) | Crystal structure of chimeric bat coronavirus BANAL-20-236 RBD complexed with chimeric mouse ACE2 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, W, Shi, K, Aihara, H, Li, F. | Deposit date: | 2023-11-15 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | Crystal structure of chimeric RBD complexed with chimeric mouse ACE2 To Be Published
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3JAU
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![BU of 3jau by Molmil](/molmil-images/mine/3jau) | The cryoEM map of EV71 mature viron in complex with the Fab fragment of antibody D5 | Descriptor: | Capsid protein VP1, Heavy chain of Fab fragment variable region of antibody D5, Light chain of Fab fragment variable region of antibody D5 | Authors: | Fan, C, Ye, X.H, Ku, Z.Q, Zuo, T, Kong, L.L, Zhang, C, Shi, J.P, Liu, Q.W, Chen, T, Zhang, Y.Y, Jiang, W, Zhang, L.Q, Huang, Z, Cong, Y. | Deposit date: | 2015-06-24 | Release date: | 2016-02-10 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody Plos Pathog., 12, 2016
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3JB6
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![BU of 3jb6 by Molmil](/molmil-images/mine/3jb6) | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, VP1 CSP, ... | Authors: | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | Deposit date: | 2015-08-02 | Release date: | 2015-10-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus. Nature, 527, 2015
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4OO2
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![BU of 4oo2 by Molmil](/molmil-images/mine/4oo2) | Streptomyces globisporus C-1027 FAD dependent (S)-3-chloro-β-tyrosine-S-SgcC2 C-5 hydroxylase SgcC apo form | Descriptor: | CALCIUM ION, Chlorophenol-4-monooxygenase, GLYCEROL | Authors: | Cao, H, Xu, W, Bingman, C.A, Lohman, J.R, Yennamalli, R, Shen, B, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2014-01-29 | Release date: | 2014-02-12 | Last modified: | 2023-03-22 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry, 55, 2016
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8UZF
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![BU of 8uzf by Molmil](/molmil-images/mine/8uzf) | Crystal structure of chimeric RaTG13 RBD complexed with chimeric mouse ACE2 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, W, Shi, K, Aihara, H, Li, F. | Deposit date: | 2023-11-15 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (3.283 Å) | Cite: | Crystal structure of chimeric RaTG13 RBD complexed with chimeric mouse ACE2 To Be Published
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4OG1
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![BU of 4og1 by Molmil](/molmil-images/mine/4og1) | Crystal Structure of a Putative Enoyl-CoA Hydratase from Novosphingobium aromaticivorans DSM 12444 | Descriptor: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Enoyl-CoA hydratase/isomerase | Authors: | Chapman, H.C, Cooper, D.R, Tkaczuk, K.L, Cymborowski, M.T, Stead, M, Hillerich, B, Ahmed, M, Bonanno, J.B, Seidel, R, Alkire, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2014-01-15 | Release date: | 2014-01-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal Structure of a Putative Enoyl-CoA Hydratase from Novosphingobium aromaticivorans DSM 12444 To be Published
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3J46
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![BU of 3j46 by Molmil](/molmil-images/mine/3j46) | Structure of the SecY protein translocation channel in action | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L23P, ... | Authors: | Akey, C.W, Park, E, Menetret, J.F, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A. | Deposit date: | 2013-06-18 | Release date: | 2013-10-23 | Last modified: | 2019-07-03 | Method: | ELECTRON MICROSCOPY (10.1 Å) | Cite: | Structure of the SecY channel during initiation of protein translocation. Nature, 506, 2013
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3JU5
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![BU of 3ju5 by Molmil](/molmil-images/mine/3ju5) | Crystal Structure of Dimeric Arginine Kinase at 1.75-A Resolution | Descriptor: | Arginine kinase, MAGNESIUM ION | Authors: | Wu, X, Ye, S, Guo, S, Yan, W, Bartlam, M, Rao, Z. | Deposit date: | 2009-09-14 | Release date: | 2009-09-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity Faseb J., 24, 2010
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7WTK
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![BU of 7wtk by Molmil](/molmil-images/mine/7wtk) | SARS-CoV-2 Omicron variant spike in complex with Fab XGv286 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of XGv286, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-02-04 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages. Cell Res., 32, 2022
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7WTJ
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![BU of 7wtj by Molmil](/molmil-images/mine/7wtj) | SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv286 | Descriptor: | Heavy chain of XGv286, Light chain of XGv286, Spike protein S1 | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-02-04 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages. Cell Res., 32, 2022
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4P7A
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![BU of 4p7a by Molmil](/molmil-images/mine/4p7a) | Crystal Structure of human MLH1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein Mlh1, MAGNESIUM ION, ... | Authors: | Tempel, W, Lam, R, Zeng, H, Walker, J.R, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2014-03-26 | Release date: | 2014-04-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome. Acta Crystallogr.,Sect.F, 71, 2015
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3JR2
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![BU of 3jr2 by Molmil](/molmil-images/mine/3jr2) | X-ray crystal structure of the Mg-bound 3-keto-L-gulonate-6-phosphate decarboxylase from Vibrio cholerae O1 biovar El Tor str. N16961 | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Hexulose-6-phosphate synthase SgbH, ... | Authors: | Nocek, B, Maltseva, N, Stam, J, Anderson, W, Joachimiak, A, CSGID, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2009-09-08 | Release date: | 2009-10-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the Mg-bound 3-keto-L-gulonate-6-phosphate
decarboxylase from Vibrio cholerae O1 biovar El Tor str. N16961 To be Published
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4P8W
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![BU of 4p8w by Molmil](/molmil-images/mine/4p8w) | The crystal structures of YKL-39 in the presence of chitooligosaccharides (GlcNAc4) were solved to resolutions of 1.9 angstrom | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Chitinase-3-like protein 2, SULFATE ION | Authors: | Suginta, W, Ranok, A, Robinson, R.C, Wongsantichon, J. | Deposit date: | 2014-04-01 | Release date: | 2014-12-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural and Thermodynamic Insights into Chitooligosaccharide Binding to Human Cartilage Chitinase 3-like Protein 2 (CHI3L2 or YKL-39). J.Biol.Chem., 290, 2015
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8WD2
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![BU of 8wd2 by Molmil](/molmil-images/mine/8wd2) | The Crystal Structure of p53 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, PHOSPHATE ION, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Lu, Y. | Deposit date: | 2023-09-14 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Crystal Structure of p53 from Biortus. To Be Published
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7WTF
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![BU of 7wtf by Molmil](/molmil-images/mine/7wtf) | SARS-CoV-2 Omicron variant spike in complex with Fab XGv051 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of XGv051, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-02-04 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages. Cell Res., 32, 2022
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8WF7
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![BU of 8wf7 by Molmil](/molmil-images/mine/8wf7) | The Crystal Structure of integrase from Biortus | Descriptor: | ACETATE ION, Integrase, SULFATE ION | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | Deposit date: | 2023-09-19 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The Crystal Structure of integrase from Biortus To Be Published
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3JVL
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![BU of 3jvl by Molmil](/molmil-images/mine/3jvl) | Crystal structure of bromodomain 2 of mouse Brd4 | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Bromodomain-containing protein 4 | Authors: | Vollmuth, F, Blankenfeldt, W, Geyer, M. | Deposit date: | 2009-09-17 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution J.Biol.Chem., 284, 2009
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7WTG
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![BU of 7wtg by Molmil](/molmil-images/mine/7wtg) | SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv051 | Descriptor: | Heavy chain of XGv051, Light chain of XGv051, Spike protein S1 | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-02-04 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages. Cell Res., 32, 2022
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4PMQ
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![BU of 4pmq by Molmil](/molmil-images/mine/4pmq) | Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with L-tartrate (orthorhombic crystal form) | Descriptor: | GLYCEROL, L(+)-TARTARIC ACID, Tat-secreted protein Rv2525c | Authors: | Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M. | Deposit date: | 2014-05-22 | Release date: | 2014-10-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c. J.Struct.Biol., 188, 2014
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7WTH
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![BU of 7wth by Molmil](/molmil-images/mine/7wth) | SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv264 | Descriptor: | Heavy chain of XGv264, Light chain of XGv264, Spike protein S1 | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-02-04 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages. Cell Res., 32, 2022
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4PNS
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![BU of 4pns by Molmil](/molmil-images/mine/4pns) | Crystal Structure of human Tankyrase 2 in complex with INH2BP. | Descriptor: | 6-amino-5-iodo-2H-chromen-2-one, GLYCEROL, Tankyrase-2, ... | Authors: | Qiu, W, Lam, R, Romanov, V, Gordon, R, Gebremeskel, S, Vodsedalek, J, Thompson, C, Beletskaya, I, Battaile, K.P, Pai, E.F, Chirgadze, N.Y. | Deposit date: | 2014-05-25 | Release date: | 2014-10-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2. Acta Crystallogr.,Sect.D, 70, 2014
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8WRB
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![BU of 8wrb by Molmil](/molmil-images/mine/8wrb) | Lysophosphatidylserine receptor GPR34-Gi complex | Descriptor: | Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Gong, W, Liu, G, Li, X, Wang, Y, Zhang, X. | Deposit date: | 2023-10-13 | Release date: | 2023-11-08 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | Structural basis for ligand recognition and signaling of the lysophosphatidylserine receptors GPR34 and GPR174. Plos Biol., 21, 2023
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8WWX
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![BU of 8wwx by Molmil](/molmil-images/mine/8wwx) | |