1U4E
 
 | | Crystal Structure of Cytoplasmic Domains of GIRK1 channel | | Descriptor: | G protein-activated inward rectifier potassium channel 1 | | Authors: | Pegan, S, Arrabit, C, Zhou, W, Kwiatkowski, W, Slesinger, P.A, Choe, S. | | Deposit date: | 2004-07-24 | | Release date: | 2005-03-08 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification
Nat.Neurosci., 8, 2005
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7M8E
 | | E.coli RNAP-RapA elongation complex | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Shi, W, Liu, B. | | Deposit date: | 2021-03-29 | | Release date: | 2021-08-18 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis for activation of Swi2/Snf2 ATPase RapA by RNA polymerase.
Nucleic Acids Res., 49, 2021
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3IHI
 | | Crystal structure of mouse thymidylate synthase | | Descriptor: | SULFATE ION, Thymidylate synthase | | Authors: | Dowiercial, A, Jarmula, A, Rypniewski, W.R, Sokolowska, M, Fraczyk, T, Ciesla, J, Rode, W. | | Deposit date: | 2009-07-30 | | Release date: | 2010-02-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme
Struct Chem, 2016
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1K5N
 | | HLA-B*2709 BOUND TO NONA-PEPTIDE M9 | | Descriptor: | GLYCEROL, beta-2-microglobulin, light chain, ... | | Authors: | Hulsmeyer, M, Hillig, R.C, Volz, A, Ruhl, M, Schroder, W, Saenger, W, Ziegler, A, Uchanska-Ziegler, B. | | Deposit date: | 2001-10-11 | | Release date: | 2002-10-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.09 Å) | | Cite: | HLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations
J.Biol.Chem., 277, 2002
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1QKJ
 | | T4 Phage B-Glucosyltransferase, Substrate Binding and Proposed Catalytic Mechanism | | Descriptor: | BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | | Authors: | Morera, S, Imberty, I, Aschke-Sonnenborn, U, Ruger, W, Freemont, P.S. | | Deposit date: | 1999-07-22 | | Release date: | 1999-07-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | T4 Phage Beta-Glucosyltransferase: Substrate Binding and Proposed Catalytic Mechanism
J.Mol.Biol., 292, 1999
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6DRJ
 | | Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, ADPR/Ca2+ bound state | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, Transient receptor potential cation channel, ... | | Authors: | Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W. | | Deposit date: | 2018-06-12 | | Release date: | 2018-09-19 | | Last modified: | 2018-10-10 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium.
Nature, 562, 2018
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2VV5
 | | The open structure of MscS | | Descriptor: | SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL | | Authors: | Wang, W, Dong, C, Johnson, K.A, Naismith, J.H. | | Deposit date: | 2008-06-03 | | Release date: | 2008-08-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | The Structure of an Open Form of an E. Coli Mechanosensitive Channel at 3.45 A Resolution.
Science, 321, 2008
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8TJ2
 | | CryoEM structure of Myxococcus xanthus type IV pilus | | Descriptor: | Type IV major pilin protein PilA | | Authors: | Zheng, W, Egelman, E.H. | | Deposit date: | 2023-07-20 | | Release date: | 2023-08-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Tight-packing of large pilin subunits provides distinct structural and mechanical properties for the Myxococcus xanthus type IVa pilus.
Proc.Natl.Acad.Sci.USA, 121, 2024
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1U4F
 | | Crystal Structure of Cytoplasmic Domains of IRK1 (Kir2.1) channel | | Descriptor: | Inward rectifier potassium channel 2 | | Authors: | Pegan, S, Arrabit, C, Zhou, W, Kwiatkowski, W, Slesinger, P.A, Choe, S. | | Deposit date: | 2004-07-24 | | Release date: | 2005-03-08 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification
Nat.Neurosci., 8, 2005
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1ETR
 | | REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS | | Descriptor: | EPSILON-THROMBIN, amino{[(4S)-5-[(2R,4R)-2-carboxy-4-methylpiperidin-1-yl]-4-({[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonyl}amino)-5-oxopentyl]amino}methaniminium | | Authors: | Bode, W, Brandstetter, H. | | Deposit date: | 1992-07-06 | | Release date: | 1994-01-31 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics.
J.Mol.Biol., 226, 1992
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2OXB
 | | Crystal structure of a cell-wall invertase (E203Q) from Arabidopsis thaliana in complex with sucrose | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-fructofuranosidase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | Authors: | Lammens, W, Le Roy, K, Van Laere, A, Van den Ende, W, Rabijns, A. | | Deposit date: | 2007-02-20 | | Release date: | 2008-01-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | An alternate sucrose binding mode in the E203Q Arabidopsis invertase mutant: An X-ray crystallography and docking study.
Proteins, 71, 2007
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6DRK
 | | Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, Apo state | | Descriptor: | Transient receptor potential cation channel, subfamily M, member 2 | | Authors: | Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W. | | Deposit date: | 2018-06-12 | | Release date: | 2018-09-19 | | Last modified: | 2018-10-10 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium.
Nature, 562, 2018
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2HD3
 | | Crystal Structure of the Ethanolamine Utilization Protein EutN from Escherichia coli, NESG Target ER316 | | Descriptor: | Ethanolamine utilization protein eutN | | Authors: | Forouhar, F, Zhang, W, Jayaraman, S, Zhao, L, Jiang, M, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-06-19 | | Release date: | 2006-08-15 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Functional insights from structural genomics.
J.STRUCT.FUNCT.GENOM., 8, 2007
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3N9T
 | | Cryatal structure of Hydroxyquinol 1,2-dioxygenase from Pseudomonas putida DLL-E4 | | Descriptor: | 1-HEPTADECANOYL-2-TRIDECANOYL-3-GLYCEROL-PHOSPHONYL CHOLINE, CITRATE ANION, FE (III) ION, ... | | Authors: | Liu, W, Shen, W, Fang, P, Li, J, Cui, Z. | | Deposit date: | 2010-05-31 | | Release date: | 2010-08-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Cryatal structure of Hydroxyquinol 1,2-dioxygenase from Pseudomonas putida DLL-E4
To be Published
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1RPR
 | | THE STRUCTURE OF COLE1 ROP IN SOLUTION | | Descriptor: | ROP | | Authors: | Eberle, W, Pastore, A, Klaus, W, Sander, C, Roesch, P. | | Deposit date: | 1991-10-09 | | Release date: | 1994-01-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The structure of ColE1 rop in solution.
J.Biomol.NMR, 1, 1991
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6V9T
 | | Tudor domain of TDRD3 in complex with a small molecule | | Descriptor: | 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, Tudor domain-containing protein 3, UNKNOWN ATOM OR ION | | Authors: | Li, W, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2019-12-16 | | Release date: | 2019-12-25 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.154 Å) | | Cite: | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.
Nat Commun, 13, 2022
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1TWL
 | | Inorganic pyrophosphatase from Pyrococcus furiosus Pfu-264096-001 | | Descriptor: | Inorganic pyrophosphatase | | Authors: | Zhou, W, Tempel, W, Liu, Z.-J, Chen, L, Clancy Kelley, L.-L, Dillard, B.D, Hopkins, R.C, Arendall III, W.B, Rose, J.P, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Richardson, J.S, Richardson, D.C, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | Deposit date: | 2004-07-01 | | Release date: | 2004-11-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Inorganic pyrophosphatase from Pyrococcus furiosus Pfu-264096-001
To be published
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7N7V
 | | Crystal structure of TtnM, a Fe(II)-alpha-ketoglutarate-dependent hydroxylase from the tautomycetin biosynthesis pathway in Streptomyces griseochromogenes at 2 A. | | Descriptor: | CHLORIDE ION, FE (II) ION, Predicted hydroxylase | | Authors: | Han, L, Xu, W, Ma, M, Miller, M.D, Shen, B, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | Deposit date: | 2021-06-11 | | Release date: | 2022-07-06 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structure of TtnM, a Fe(II)-alpha-ketoglutarate-dependent hydroxylase from the tautomycetin biosynthesis pathway in Streptomyces griseochromogenes.
To Be Published
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1ZBP
 | | X-Ray Crystal Structure of Protein VPA1032 from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium Target VpR44 | | Descriptor: | hypothetical protein VPA1032 | | Authors: | Forouhar, F, Yong, W, Vorobiev, S.M, Ciao, M, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2005-04-08 | | Release date: | 2005-04-19 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Functional insights from structural genomics.
J.STRUCT.FUNCT.GENOM., 8, 2007
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4HJR
 | | Crystal structure of F2YRS | | Descriptor: | Tyrosine-tRNA ligase | | Authors: | Wang, J, Tian, C, Gong, W, Li, F, Shi, P, Li, J, Ding, W. | | Deposit date: | 2012-10-13 | | Release date: | 2013-03-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A genetically encoded 19F NMR probe for tyrosine phosphorylation.
Angew.Chem.Int.Ed.Engl., 52, 2013
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1NLF
 | | Crystal Structure of DNA Helicase RepA in complex with sulfate at 1.95 A resolution | | Descriptor: | Regulatory protein repA, SULFATE ION | | Authors: | Xu, H, Strater, N, Schroeder, W, Bottcher, C, Ludwig, K, Saenger, W. | | Deposit date: | 2003-01-07 | | Release date: | 2003-04-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure of DNA helicase RepA in complex with sulfate at 1.95 A resolution implicates structural changes to an "open" form.
Acta Crystallogr.,Sect.D, 59, 2003
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1TPO
 | | THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS | | Descriptor: | BETA-TRYPSIN, CALCIUM ION | | Authors: | Bode, W, Walter, J, Huber, R. | | Deposit date: | 1982-09-27 | | Release date: | 1983-01-18 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors
Acta Crystallogr.,Sect.B, 39, 1983
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4Y2M
 | | apo-GolB protein | | Descriptor: | GOLD ION, Putative metal-binding transport protein | | Authors: | Wei, W, Zhao, J, Wang, F. | | Deposit date: | 2015-02-10 | | Release date: | 2016-02-10 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015
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2P4Q
 | | Crystal Structure Analysis of Gnd1 in Saccharomyces cerevisiae | | Descriptor: | 6-phosphogluconate dehydrogenase, decarboxylating 1, CITRATE ANION | | Authors: | He, W, Wang, Y, Liu, W, Zhou, C.Z. | | Deposit date: | 2007-03-12 | | Release date: | 2007-07-24 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1
Bmc Struct.Biol., 7, 2007
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1ETT
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