6V9T
Tudor domain of TDRD3 in complex with a small molecule
This is a non-PDB format compatible entry.
Summary for 6V9T
Entry DOI | 10.2210/pdb6v9t/pdb |
Descriptor | Tudor domain-containing protein 3, 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, UNKNOWN ATOM OR ION, ... (4 entities in total) |
Functional Keywords | structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 18590.94 |
Authors | Li, W.,Tempel, W.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2019-12-16, release date: 2019-12-25, Last modification date: 2023-10-18) |
Primary citation | Liu, Y.,Iqbal, A.,Li, W.,Ni, Z.,Wang, Y.,Ramprasad, J.,Abraham, K.J.,Zhang, M.,Zhao, D.Y.,Qin, S.,Loppnau, P.,Jiang, H.,Guo, X.,Brown, P.J.,Zhen, X.,Xu, G.,Mekhail, K.,Ji, X.,Bedford, M.T.,Greenblatt, J.F.,Min, J. A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13:5453-5453, 2022 Cited by PubMed: 36114190DOI: 10.1038/s41467-022-33229-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.154 Å) |
Structure validation
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