8GXQ
 
 | | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | 著者 | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y. | | 登録日 | 2022-09-21 | | 公開日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (5.04 Å) | | 主引用文献 | Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
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1ZK1
 | | Structure of R-specific alcohol dehydrogenase (mutant G37D) from Lactobacillus brevis in complex with phenylethanol and NAD | | 分子名称: | 1-PHENYLETHANONE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Schlieben, N.H, Niefind, K, Muller, J, Riebel, B, Hummel, W, Schomburg, D. | | 登録日 | 2005-05-02 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Atomic Resolution Structures of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Provide the Structural Bases of its Substrate and Cosubstrate Specificity
J.Mol.Biol., 349, 2005
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8GSF
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8GSD
 | | Echovirus3 full particle in complex with 6D10 Fab | | 分子名称: | Genome polyprotein, Genome polyprotein (Fragment), Heavy chain of 6D10, ... | | 著者 | Wang, X, Fu, W. | | 登録日 | 2022-09-06 | | 公開日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural Basis for the Immunogenicity of the C-Terminus of VP1 of Echovirus 3 Revealed by the Binding of a Neutralizing Antibody.
Viruses, 14, 2022
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8GSE
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8GSC
 | | Echovirus3 A-particle in complex with 6D10 Fab | | 分子名称: | Heavy chain of 6D10, Light chain of 6D10, VP1, ... | | 著者 | Wang, X, Fu, W. | | 登録日 | 2022-09-06 | | 公開日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural Basis for the Immunogenicity of the C-Terminus of VP1 of Echovirus 3 Revealed by the Binding of a Neutralizing Antibody.
Viruses, 14, 2022
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5YTK
 | | Crystal structure of SIRT3 bound to a leucylated AceCS2 | | 分子名称: | AceCS2-KLeu, LEUCINE, LYSINE, ... | | 著者 | Li, J, Gong, W, Xu, Y. | | 登録日 | 2017-11-18 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations
Cell Metab., 27, 2018
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8CH7
 | | RDC-refined Interleukin-4 (wild type) pH 5.6 | | 分子名称: | Interleukin-4 | | 著者 | Vaz, D.C, Rodrigues, J.R, Loureiro-Ferreira, N, Mueller, T, Sebald, W, Redfield, C, Brito, R.M.M. | | 登録日 | 2023-02-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Proteins, 92, 2024
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8CGF
 | | Interleukin-4 (wild type) pH 2.4 | | 分子名称: | Interleukin-4 | | 著者 | Vaz, D.C, Rodrigues, J.R, Loureiro-Ferreira, N, Mueller, T, Sebald, W, Redfield, C, Brito, R.M.M. | | 登録日 | 2023-02-04 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Proteins, 92, 2024
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8CWL
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8DB3
 | | Crystal structure of KaiC with truncated C-terminal coiled-coil domain | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC | | 著者 | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | 登録日 | 2022-06-14 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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8DFM
 | | Ectodomain of full-length wild-type KIT-SCF dimers | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | | 著者 | Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. | | 登録日 | 2022-06-22 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8DFQ
 | | Ectodomain of full-length KIT(T417I,delta418-419)-SCF dimers | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | | 著者 | Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. | | 登録日 | 2022-06-22 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8DBA
 | | Crystal structure of dodecameric KaiC | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC, MAGNESIUM ION | | 著者 | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | 登録日 | 2022-06-14 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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8CW2
 | | Crystal structure of TDP1 complexed with compound XZ760 | | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-({(4R)-7-phenyl-2-[4-(2-{[4-(pyridin-2-yl)phenyl]methoxy}ethyl)phenyl]imidazo[1,2-a]pyridin-3-yl}amino)benzene-1,2-dicarboxylic acid, ... | | 著者 | Lountos, G.T, Zhao, X.Z, Wang, W, Kiselev, E, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R. | | 登録日 | 2022-05-18 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.811 Å) | | 主引用文献 | Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification.
Rsc Chem Biol, 4, 2023
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8DFP
 | | Ectodomain of full-length KIT(DupA502,Y503)-SCF dimers | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | | 著者 | Bertoletti, N, Krimmer, S.G, Mi, W, Schlessinger, J. | | 登録日 | 2022-06-22 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EHW
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8CVQ
 | | Crystal structure of TDP1 complexed with compound XZ761 | | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-{[(4S)-2,7-diphenylimidazo[1,2-a]pyridin-3-yl]amino}benzene-1,2-dicarboxylic acid, ... | | 著者 | Lountos, G.T, Zhao, X.Z, Wang, W, Kiselev, E, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R. | | 登録日 | 2022-05-18 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification.
Rsc Chem Biol, 4, 2023
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1ZK4
 | | Structure of R-specific alcohol dehydrogenase (wildtype) from Lactobacillus brevis in complex with acetophenone and NADP | | 分子名称: | 1-PHENYLETHANONE, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Schlieben, N.H, Niefind, K, Muller, J, Riebel, B, Hummel, W, Schomburg, D. | | 登録日 | 2005-05-02 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Atomic Resolution Structures of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Provide the Structural Bases of its Substrate and Cosubstrate Specificity
J.Mol.Biol., 349, 2005
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4DXY
 | | Crystal structures of CYP101D2 Y96A mutant | | 分子名称: | Cytochrome P450, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Zhou, W, Bell, S.G, Yang, W, Dale, A, Wong, L.-L. | | 登録日 | 2012-02-28 | | 公開日 | 2012-08-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Improving the affinity and activity of CYP101D2 for hydrophobic substrates
Appl.Microbiol.Biotechnol., 2012
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8GQR
 | | Crystal structure of VioD with FAD | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ... | | 著者 | Ran, T, Wang, W, Xu, M. | | 登録日 | 2022-08-30 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of the key enzyme VioD in the violacein synthesis pathway.
Proteins, 91, 2023
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2WSW
 | | Crystal Structure of Carnitine Transporter from Proteus mirabilis | | 分子名称: | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, BCCT FAMILY BETAINE/CARNITINE/CHOLINE TRANSPORTER, GLYCEROL, ... | | 著者 | Schulze, S, Terwisscha van Scheltinga, A.C, Kuehlbrandt, W. | | 登録日 | 2009-09-10 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.294 Å) | | 主引用文献 | Structural Basis of Na(+)-Independent and Cooperative Substrate/Product Antiport in Cait.
Nature, 467, 2010
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8GYN
 | | zebrafish TIPE1 strucutre in complex with PE | | 分子名称: | Tumor necrosis factor alpha-induced protein 8-like protein 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | 著者 | Wang, W, Cao, S.J. | | 登録日 | 2022-09-23 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Structural insight into TIPE1 functioning as a lipid transfer protein.
J.Biomol.Struct.Dyn., 41, 2023
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4E44
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5WP3
 | | Crystal Structure of EED in complex with EB22 | | 分子名称: | EB22, Polycomb protein EED, UNKNOWN ATOM OR ION | | 著者 | Dong, C, Tempel, W, Zhu, L, Moody, J.D, Baker, D, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2017-08-03 | | 公開日 | 2017-09-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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