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PDB: 12487 件

7EX3
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Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 3
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX4
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BU of 7ex4 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 5
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7F3A
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BU of 7f3a by Molmil
Arabidopsis thaliana GH1 beta-glucosidase AtBGlu42
分子名称: Beta-glucosidase 42, GLYCEROL
著者Horikoshi, S, Saburi, W, Yu, J, Yao, M.
登録日2021-06-16
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Substrate specificity of glycoside hydrolase family 1 beta-glucosidase AtBGlu42 from Arabidopsis thaliana and its molecular mechanism.
Biosci.Biotechnol.Biochem., 86, 2022
4RCJ
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BU of 4rcj by Molmil
Crystal structure of YTHDF1 YTH domain in complex with 5mer m6A RNA
分子名称: RNA (5'-R(*GP*GP*(6MZ)P*CP*U)-3'), UNKNOWN ATOM OR ION, YTH domain-containing family protein 1
著者Tempel, W, Xu, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2014-09-16
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.
J.Biol.Chem., 290, 2015
2KLV
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BU of 2klv by Molmil
Membrane-bound structure of the Pf1 major coat protein in DHPC micelle
分子名称: Capsid protein G8P
著者Park, S, Son, W, Mukhopadhyay, R, Valafar, H, Opella, S.J.
登録日2009-07-08
公開日2009-10-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Phage-induced alignment of membrane proteins enables the measurement and structural analysis of residual dipolar couplings with dipolar waves and lambda-maps.
J.Am.Chem.Soc., 131, 2009
7FCI
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BU of 7fci by Molmil
human NTCP in complex with YN69083 Fab
分子名称: Fab Heavy chain, Fab Light chain, Sodium/bile acid cotransporter
著者Park, J.H, Iwamoto, M, Yun, J.H, Uchikubo-Kamo, T, Son, D, Jin, Z, Yoshida, H, Ohki, M, Ishimoto, N, Mizutani, K, Oshima, M, Muramatsu, M, Wakita, T, Shirouzu, M, Liu, K, Uemura, T, Nomura, N, Iwata, S, Watashi, K, Tame, J.R.H, Nishizawa, T, Lee, W, Park, S.Y.
登録日2021-07-14
公開日2022-05-25
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the HBV receptor and bile acid transporter NTCP.
Nature, 606, 2022
2ID1
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BU of 2id1 by Molmil
X-Ray Crystal Structure of Protein CV0518 from Chromobacterium violaceum, Northeast Structural Genomics Consortium Target CvR5.
分子名称: Hypothetical protein, IODIDE ION
著者Forouhar, F, Zhou, W, Seetharaman, J, Ho, C.K, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2006-09-13
公開日2006-09-26
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献

4QQG
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BU of 4qqg by Molmil
Crystal structure of an N-terminal HTATIP fragment
分子名称: Histone acetyltransferase KAT5, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Wernimont, A.K, Dobrovetsky, E, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2014-06-27
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and histone binding studies of the chromo barrel domain of TIP60.
FEBS Lett., 592, 2018
4RCM
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BU of 4rcm by Molmil
Crystal structure of the Pho92 YTH domain in complex with m6A
分子名称: Methylated RNA-binding protein 1, RNA (5'-R(*UP*G)-D(*(6MZ)P*CP*U)-3'), UNKNOWN ATOM OR ION
著者Tempel, W, Xu, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2014-09-16
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.
J.Biol.Chem., 290, 2015
2IDU
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BU of 2idu by Molmil
Structure of M98Q mutant of amicyanin, Cu(I)
分子名称: Amicyanin, COPPER (I) ION
著者Carrell, C.J, Ma, J.K, Antholine, W, Hosler, J.P, Mathews, F.S, Davidson, V.L.
登録日2006-09-15
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Generation of Novel Copper Sites by Mutation of the Axial Ligand of Amicyanin. Atomic Resolution Structures and Spectroscopic Properties
Biochemistry, 46, 2007
3N9Z
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BU of 3n9z by Molmil
Crystal structure of human CYP11A1 in complex with 22-hydroxycholesterol
分子名称: (3alpha,8alpha,22R)-cholest-5-ene-3,22-diol, Adrenodoxin, Cholesterol side-chain cleavage enzyme, ...
著者Strushkevich, N.V, MacKenzie, F, Tempel, W, Botchkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J.U, Park, H, Structural Genomics Consortium (SGC)
登録日2010-05-31
公開日2011-06-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system.
Proc.Natl.Acad.Sci.USA, 108, 2011
2K0Y
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BU of 2k0y by Molmil
The actinorhodin apo acyl carrier protein from S. coelicolor
分子名称: Actinorhodin polyketide synthase acyl carrier protein
著者Crump, M.P, Evans, S.E, Christopher, W.
登録日2008-02-15
公開日2008-09-16
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein.
Chembiochem, 9, 2008
7EOZ
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BU of 7eoz by Molmil
The structure of rice Defective Pollen Wall (DPW) in the complex with its cofactor NADP
分子名称: Fatty acyl-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Yan, L.M, Wang, W, Li, G, Wang, J.
登録日2021-04-24
公開日2022-08-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Defective Pollen Wall Bridges Lipid and Sugar Metabolisms in Plant Male Reproductive Development
To Be Published
4QQN
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BU of 4qqn by Molmil
Protein arginine methyltransferase 3 in complex with compound MTV044246
分子名称: 1-{2-[1-(aminomethyl)cyclohexyl]ethyl}-3-isoquinolin-6-ylurea, CHLORIDE ION, GLYCEROL, ...
著者Dong, A, Dobrovetsky, E, Tempel, W, He, H, Zhao, K, Smil, D, Landon, M, Luo, X, Chen, Z, Dai, M, Yu, Z, Lin, Y, Zhang, H, Zhao, K, Schapira, M, Brown, P.J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Vedadi, M, Structural Genomics Consortium (SGC)
登録日2014-06-27
公開日2014-09-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3).
J. Med. Chem., 61, 2018
7FI9
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BU of 7fi9 by Molmil
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
分子名称: GLYCEROL, MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein
著者Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J.
登録日2021-07-30
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
7FI7
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BU of 7fi7 by Molmil
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
分子名称: MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein
著者Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J.
登録日2021-07-30
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
7FI8
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BU of 7fi8 by Molmil
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
分子名称: MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein
著者Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J.
登録日2021-07-30
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
7FI6
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BU of 7fi6 by Molmil
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
分子名称: MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein
著者Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J.
登録日2021-07-30
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
7FI5
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BU of 7fi5 by Molmil
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
分子名称: GLYCEROL, MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein
著者Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J.
登録日2021-07-30
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
7JYS
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BU of 7jys by Molmil
hALK in complex with 3-(3-chlorophenyl)-5-methyl-1H-pyrazole
分子名称: 1,2-ETHANEDIOL, 3-(3-chlorophenyl)-5-methyl-1H-pyrazole, ALK tyrosine kinase receptor
著者McGrath, A.P, Zou, H, Lane, W, Saikatendu, K.
登録日2020-08-31
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Discovery of Novel and Highly Selective Cyclopropane ALK Inhibitors through a Fragment-Assisted, Structure-Based Drug Design.
Acs Omega, 5, 2020
4RCH
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BU of 4rch by Molmil
Discovery of 2-Pyridyl Ureas as Glucokinase Activators
分子名称: 1-{3-[(2-ethylpyridin-3-yl)oxy]-5-(pyridin-2-ylsulfanyl)pyridin-2-yl}-3-methylurea, Glucokinase, alpha-D-glucopyranose
著者Voegtli, W, Vigers, G.P.A.
登録日2014-09-16
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of 2-pyridylureas as glucokinase activators.
J.Med.Chem., 57, 2014
7JQ3
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BU of 7jq3 by Molmil
Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI6
分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-threonyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Yang, K, Liu, W.
登録日2020-08-10
公開日2020-12-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*.
Chemmedchem, 16, 2021
4R6L
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BU of 4r6l by Molmil
Crystal structure of bacteriophytochrome RpBphP2 from photosynthetic bacterium R. palustris
分子名称: BILIVERDINE IX ALPHA, Bacteriophytochrome (Light-regulated signal transduction histidine kinase), PhyB1
著者Yang, X, Stojkovic, E, Ozarowski, W, Kuk, J, Davydova, E, Moffat, K.
登録日2014-08-25
公開日2015-07-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.395 Å)
主引用文献Light Signaling Mechanism of Two Tandem Bacteriophytochromes.
Structure, 23, 2015
7JYR
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hALK in complex with 1-[(1R,2R)-1-(2,4-difluorophenyl)-2-[2-(5-methyl-1H-pyrazol-3-yl)-4-(trifluoromethyl)phenoxy]cyclopropyl]methanamine
分子名称: 1,2-ETHANEDIOL, 4-{[(1R,2R)-2-(2,4-difluorophenyl)cyclopropyl]oxy}-3-(5-methyl-1H-pyrazol-3-yl)benzonitrile, ALK tyrosine kinase receptor
著者McGrath, A.P, Zou, H, Lane, W, Saikatendu, K.
登録日2020-08-31
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Discovery of Novel and Highly Selective Cyclopropane ALK Inhibitors through a Fragment-Assisted, Structure-Based Drug Design.
Acs Omega, 5, 2020
4RCI
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BU of 4rci by Molmil
Crystal structure of YTHDF1 YTH domain
分子名称: UNKNOWN ATOM OR ION, YTH domain-containing family protein 1
著者Xu, C, Tempel, W, Liu, K, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2014-09-16
公開日2014-10-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.
J.Biol.Chem., 290, 2015

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件を2024-07-17に公開中

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