6IRB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6irb by Molmil](/molmil-images/mine/6irb) | C-terminal coiled coil domain of Drosophila phospholipase C beta NORPA, selenomethionine | 分子名称: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase | 著者 | Ye, F, Li, J, Huang, Y, Liu, W, Zhang, M. | 登録日 | 2018-11-12 | 公開日 | 2019-01-02 | 最終更新日 | 2020-10-28 | 実験手法 | X-RAY DIFFRACTION (2.661 Å) | 主引用文献 | An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors. Elife, 7, 2018
|
|
6IS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6is6 by Molmil](/molmil-images/mine/6is6) | Crystal structure of Thermoplasmatales archaeon heliorhodopsin | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, RETINAL, heliorhodopsin | 著者 | Shihoya, W, Yamashita, K, Nureki, O. | 登録日 | 2018-11-15 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of heliorhodopsin. Nature, 574, 2019
|
|
6IBW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ibw by Molmil](/molmil-images/mine/6ibw) | Crh5 transglycosylase in complex with NAG | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Probable glycosidase crf1 | 著者 | Fang, W, Bartual, S.G, van Aalten, D.M.F. | 登録日 | 2018-12-01 | 公開日 | 2019-02-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases. Nat Commun, 10, 2019
|
|
6IF8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6if8 by Molmil](/molmil-images/mine/6if8) | Aeromonas hydrophila MtaN-2 complexed with adenine | 分子名称: | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE | 著者 | Chen, J, Liu, W, Wang, L, Shang, F, Lan, J, Chen, Y, Xu, Y. | 登録日 | 2018-09-18 | 公開日 | 2018-10-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Aeromonas hydrophila MtaN-2 complexed with adenine To Be Published
|
|
6MRW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mrw by Molmil](/molmil-images/mine/6mrw) | 14-meric ClyA pore complex | 分子名称: | Hemolysin E, chromosomal | 著者 | Peng, W, de Souza Santos, M, Li, Y, Tomchick, D.R, Orth, K. | 登録日 | 2018-10-15 | 公開日 | 2019-05-15 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers. Plos One, 14, 2019
|
|
6J0Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j0z by Molmil](/molmil-images/mine/6j0z) | Crystal structure of AlpK | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Putative angucycline-like polyketide oxygenase | 著者 | Wang, W, Liu, Y, Liang, H. | 登録日 | 2018-12-27 | 公開日 | 2019-03-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.889 Å) | 主引用文献 | Crystal structure of AlpK: An essential monooxygenase involved in the biosynthesis of kinamycin Biochem. Biophys. Res. Commun., 510, 2019
|
|
6JAX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jax by Molmil](/molmil-images/mine/6jax) | Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with chitooctaose [(GlcN)8] | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, Group II chitinase | 著者 | Chen, W, Zhou, Y, Yang, Q. | 登録日 | 2019-01-25 | 公開日 | 2019-05-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition. J.Biol.Chem., 294, 2019
|
|
6JOF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jof by Molmil](/molmil-images/mine/6jof) | Crystal structure of TrmD from Mycobacterium tuberculosis in complex with active-site inhibitor | 分子名称: | tRNA (guanine-N(1)-)-methyltransferase, ~{N}-[[4-[(4-azanylpiperidin-1-yl)methyl]phenyl]methyl]-4-oxidanylidene-3~{H}-thieno[2,3-d]pyrimidine-5-carboxamide | 著者 | Zhong, W, Pasunooti, K.K, Balamkundu, S, Wong, Y.W, Nah, Q, Liu, C.F, Lescar, J, Dedon, P.C. | 登録日 | 2019-03-20 | 公開日 | 2019-09-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism. J.Med.Chem., 62, 2019
|
|
6N7W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n7w by Molmil](/molmil-images/mine/6n7w) | Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes) | 分子名称: | DNA (25-MER), DNA (77-MER), DNA-directed DNA polymerase, ... | 著者 | Gao, Y, Fox, T, Val, N, Yang, W. | 登録日 | 2018-11-28 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6JR0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jr0 by Molmil](/molmil-images/mine/6jr0) | Crystal structure of the human nucleosome phased with 12 selenium atoms | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | 著者 | Saotome, M, Horikoshi, N, Urano, K, Kujirai, T, Yuzurihara, H, Kurumizaka, H, Kagawa, W. | 登録日 | 2019-04-02 | 公開日 | 2019-10-02 | 最終更新日 | 2019-10-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure determination of the nucleosome core particle by selenium SAD phasing. Acta Crystallogr D Struct Biol, 75, 2019
|
|
6JCN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jcn by Molmil](/molmil-images/mine/6jcn) | Yeast dehydrodolichyl diphosphate synthase complex subunit NUS1 | 分子名称: | Dehydrodolichyl diphosphate synthase complex subunit NUS1, SULFATE ION | 著者 | Ko, T.-P, Ma, J, Liu, W, Chen, C.-C, Guo, R.-T. | 登録日 | 2019-01-29 | 公開日 | 2019-06-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Structural insights to heterodimeric cis-prenyltransferases through yeast dehydrodolichyl diphosphate synthase subunit Nus1. Biochem.Biophys.Res.Commun., 515, 2019
|
|
6MIW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6miw by Molmil](/molmil-images/mine/6miw) | WWE domain of human HUWE1 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, E3 ubiquitin-protein ligase HUWE1, UNKNOWN ATOM OR ION | 著者 | Halabelian, L, Loppnau, P, Tempel, W, Wong, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2018-09-20 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | WWE domain of human HUWE1 To Be Published
|
|
6N7S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n7s by Molmil](/molmil-images/mine/6n7s) | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form II) | 分子名称: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | 登録日 | 2018-11-28 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6JC3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jc3 by Molmil](/molmil-images/mine/6jc3) | The Cryo-EM structure of nucleoprotein-RNA complex of Newcastle disease virus | 分子名称: | Nucleocapsid, polyU | 著者 | Song, X, Shan, H, Zhu, Y, Ding, W, Ouyang, S, Shen, Q.T, Liu, Z.J. | 登録日 | 2019-01-28 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Self-capping of nucleoprotein filaments protects the Newcastle disease virus genome. Elife, 8, 2019
|
|
6JCC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jcc by Molmil](/molmil-images/mine/6jcc) | |
6JCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jcf by Molmil](/molmil-images/mine/6jcf) | Cryogenic structure of HIV-1 Integrase catalytic core domain by synchrotron | 分子名称: | CACODYLATE ION, Integrase | 著者 | Park, J.H, Han, J, Kim, T.H, Yun, J.H, Lee, W. | 登録日 | 2019-01-28 | 公開日 | 2019-07-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.153 Å) | 主引用文献 | Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers. Int J Mol Sci, 20, 2019
|
|
6JFU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jfu by Molmil](/molmil-images/mine/6jfu) | Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) | 分子名称: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, non-target strand, ... | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | 登録日 | 2019-02-12 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
|
|
6JIJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jij by Molmil](/molmil-images/mine/6jij) | |
6JJ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jj7 by Molmil](/molmil-images/mine/6jj7) | Crystal structure of OsHXK6-Glc complex | 分子名称: | Rice hexokinase 6, beta-D-glucopyranose | 著者 | He, C, Wei, P, Chen, J, Wang, H, Wan, Y, Zhou, J, Zhu, Y, Huang, W, Yin, L. | 登録日 | 2019-02-25 | 公開日 | 2019-07-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of OsHXK6-Glc complex To Be Published
|
|
6JC4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jc4 by Molmil](/molmil-images/mine/6jc4) | |
6N7V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n7v by Molmil](/molmil-images/mine/6n7v) | Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes) | 分子名称: | DNA (93-MER), DNA primase/helicase, MAGNESIUM ION, ... | 著者 | Gao, Y, Fox, T, Val, N, Yang, W. | 登録日 | 2018-11-28 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6N7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n7n by Molmil](/molmil-images/mine/6n7n) | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I) | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ... | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | 登録日 | 2018-11-27 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6N9W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n9w by Molmil](/molmil-images/mine/6n9w) | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2) | 分子名称: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | 登録日 | 2018-12-04 | 公開日 | 2019-03-06 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6HAX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hax by Molmil](/molmil-images/mine/6hax) | Crystal structure of PROTAC 2 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB | 分子名称: | (2~{S},4~{R})-~{N}-[[2-[2-[4-[[4-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazin-1-yl]methyl]phenyl]ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Roy, M, Bader, G, Diers, E, Trainor, N, Farnaby, W, Ciulli, A. | 登録日 | 2018-08-09 | 公開日 | 2019-06-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat.Chem.Biol., 15, 2019
|
|
6NEY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ney by Molmil](/molmil-images/mine/6ney) | Crystal structure of TcBDF5, a bromodomain containing protein from Trypanosoma cruzi | 分子名称: | Uncharacterized protein | 著者 | Loppnau, P, Dong, A, Tempel, W, Lin, Y.H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Vedadi, M, Harding, R.J, Structural Genomics Consortium (SGC) | 登録日 | 2018-12-18 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Crystal structure of TcBDF5, a bromodomain containing protein from Trypanosoma cruzi To Be Published
|
|