6L1K
 
 | | Crystal structure of NADH-dependent butanol dehydrogenase A from Fusobacterium nucleatum | | 分子名称: | NADH-dependent butanol dehydrogenase A, PHOSPHATE ION | | 著者 | Lan, J, Shang, F, Liu, W, Xu, Y, Chen, Y. | | 登録日 | 2019-09-29 | | 公開日 | 2019-10-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Crystal structure of NADH-dependent butanol dehydrogenase A from Fusobacterium nucleatum
To Be Published
|
|
6L2A
 | |
6J57
 | | Crystal structure of fumarylpyruvate hydrolase from Corynebacterium glutamicum | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Predicted 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase, ... | | 著者 | Hong, H, Seo, H, Kim, K.-J, Park, W. | | 登録日 | 2019-01-10 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Sequence, structure and function-based classification of the broadly conserved FAH superfamily reveals two distinct fumarylpyruvate hydrolase subfamilies.
Environ.Microbiol., 22, 2020
|
|
6JAW
 | | Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with a napthalimide derivative | | 分子名称: | 2-[3-(morpholin-4-yl)propyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, Group II chitinase | | 著者 | Chen, W, Zhou, Y, Yang, Q. | | 登録日 | 2019-01-25 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | | 主引用文献 | Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition.
J.Biol.Chem., 294, 2019
|
|
6JE9
 | | Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers | | 分子名称: | AcrIIC3, CRISPR-associated endonuclease Cas9, sgRNA | | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | | 登録日 | 2019-02-04 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
|
|
6J44
 | | Crystal structure of the redefined DNA-binding domain of human XPA | | 分子名称: | DNA repair protein complementing XP-A cells, ZINC ION | | 著者 | Lian, F.M, Yang, X, Yang, W, Jiang, Y.L, Qian, C. | | 登録日 | 2019-01-07 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Structural characterization of the redefined DNA-binding domain of human XPA.
Biochem.Biophys.Res.Commun., 514, 2019
|
|
6L2L
 | |
6JAV
 | | Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with a piperidine-thienopyridine derivative | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[(4-chlorophenyl)methyl]sulfanyl}-7-methyl-N-(prop-2-en-1-yl)-7,8-dihydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine, Group II chitinase | | 著者 | Chen, W, Zhou, Y, Yang, Q. | | 登録日 | 2019-01-25 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.437 Å) | | 主引用文献 | Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition.
J.Biol.Chem., 294, 2019
|
|
6L13
 | | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | | 分子名称: | 2-chloranyl-10-(2-piperidin-4-ylethyl)phenoxazine, Serine/threonine-protein kinase pim-1 | | 著者 | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | | 登録日 | 2019-09-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2020-07-08 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors.
J.Chem.Inf.Model., 60, 2020
|
|
6L14
 | | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | | 分子名称: | 2-chloranyl-10-[3-[(3~{S})-piperidin-3-yl]propyl]phenoxazine, Serine/threonine-protein kinase pim-1 | | 著者 | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | | 登録日 | 2019-09-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors.
J.Chem.Inf.Model., 60, 2020
|
|
6JBO
 | | Crystal structure of EfeO-like protein Algp7 containing samarium ion | | 分子名称: | 1,2-ETHANEDIOL, Alginate-binding protein, CITRIC ACID | | 著者 | Okumura, K, Takase, R, Maruyama, Y, Mikami, B, Murata, K, Hashimoto, W. | | 登録日 | 2019-01-26 | | 公開日 | 2020-01-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Rare metal binding by a cell-surface component of bacterial EfeUOB iron importer
To Be Published
|
|
6J6V
 | |
6L2M
 | |
6J5Y
 | | Crystal structure of fumarylpyruvate hydrolase from Pseudomonas aeruginosa in complex with Mn2+ and pyruvate | | 分子名称: | FAA hydrolase family protein, MANGANESE (II) ION, PYRUVIC ACID | | 著者 | Hong, H, Seo, H, Kim, K.-J, Park, W. | | 登録日 | 2019-01-12 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Sequence, structure and function-based classification of the broadly conserved FAH superfamily reveals two distinct fumarylpyruvate hydrolase subfamilies.
Environ.Microbiol., 22, 2020
|
|
6IYY
 | |
6L7Z
 | | Solution NMR structure of the N-terminal immunoglobulin variable domain of BTNL2 | | 分子名称: | Butyrophilin-like protein 2 | | 著者 | Basak, A.J, Lee, W, Samanta, D, De, S. | | 登録日 | 2019-11-03 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Insights into N-terminal IgV Domain of BTNL2, a T Cell Inhibitory Molecule, Suggests a Non-canonical Binding Interface for Its Putative Receptors.
J.Mol.Biol., 432, 2020
|
|
6L8R
 | | membrane-bound PD-L1-CD | | 分子名称: | Programmed cell death 1 ligand 1 | | 著者 | Maorong, W, Cao, Y, Bin, W, Bo, O. | | 登録日 | 2019-11-07 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain.
Nat Commun, 12, 2021
|
|
6KQV
 | | Solution Structure of the UbL Domain of USP19 | | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 19 | | 著者 | Xue, W, Hu, H.Y. | | 登録日 | 2019-08-19 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation.
Biochem.J., 477, 2020
|
|
6JAY
 | | Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with a dipyrido-pyrimidine derivative | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-1-[(furan-2-yl)methyl]-5-oxo-3-({[(2S)-oxolan-2-yl]methyl}carbamoyl)-5H-dipyrido[1,2-a:2',3'-d]pyrimidin-1-ium, Group II chitinase | | 著者 | Chen, W, Zhou, Y, Yang, Q. | | 登録日 | 2019-01-25 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.498 Å) | | 主引用文献 | Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition.
J.Biol.Chem., 294, 2019
|
|
6JBN
 | | Crystal structure of Sphingomonas sp. A1 peroxidase EfeB responsible for import of iron | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, OXYGEN MOLECULE, ... | | 著者 | Okumura, K, Takase, R, Mikami, B, Murata, K, Hashimoto, W. | | 登録日 | 2019-01-26 | | 公開日 | 2020-01-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Rare metal binding by a cell-surface component of bacterial EfeUOB iron importer
To Be Published
|
|
6JOE
 | | Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor | | 分子名称: | PHOSPHATE ION, S-ADENOSYLMETHIONINE, tRNA (guanine-N(1)-)-methyltransferase, ... | | 著者 | Zhong, W, Pasunooti, K.K, Balamkundu, S, Wong, Y.W, Nah, Q, Liu, C.F, Lescar, J, Dedon, P.C. | | 登録日 | 2019-03-20 | | 公開日 | 2019-09-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
J.Med.Chem., 62, 2019
|
|
6M0X
 | | Crystal structure of Streptococcus thermophilus Cas9 in complex with AGGA PAM | | 分子名称: | BARIUM ION, CRISPR-associated endonuclease Cas9 1, DNA (28-MER), ... | | 著者 | Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q. | | 登録日 | 2020-02-23 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.561 Å) | | 主引用文献 | Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
|
|
6JE4
 | | Crystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomers | | 分子名称: | 1,2-ETHANEDIOL, AcrIIC3, CRISPR-associated endonuclease Cas9, ... | | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | | 登録日 | 2019-02-04 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.069 Å) | | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
|
|
6MDQ
 | | Crystal structure of equine serum albumin in complex with testosterone | | 分子名称: | CITRATE ANION, Serum albumin, TESTOSTERONE | | 著者 | Czub, M.P, Majorek, K.A, Shabalin, I.G, Handing, K.B, Venkataramany, B.S, Cymborowski, M.T, Satchell, K.J, Joachimiak, A, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2018-09-05 | | 公開日 | 2018-09-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Testosterone meets albumin - the molecular mechanism of sex hormone transport by serum albumins.
Chem Sci, 10, 2019
|
|
6M0V
 | | Crsytal structure of streptococcus thermophilus Cas9 in complex with the GGAA PAM | | 分子名称: | BARIUM ION, CRISPR-associated endonuclease Cas9 1, DNA (28-MER), ... | | 著者 | Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q. | | 登録日 | 2020-02-22 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
|
|
