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PDB: 12479 件

5XJX
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Pre-formed plant receptor ERL1-TMM complex
分子名称: LRR receptor-like serine/threonine-protein kinase ERL1, Protein TOO MANY MOUTHS
著者Chai, J, Lin, G, Zhang, L, Han, Z, Yang, X, Liu, W, Qi, Y, Chang, J, Li, E.
登録日2017-05-04
公開日2019-01-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.055 Å)
主引用文献A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017
5XK8
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Crystal structure of Isosesquilavandulyl Diphosphate Synthase from Streptomyces sp. strain CNH-189 in complex with GPP
分子名称: GERANYL DIPHOSPHATE, MAGNESIUM ION, Undecaprenyl diphosphate synthase
著者Ko, T.P, Guo, R.T, Liu, W, Chen, C.C, Gao, J.
登録日2017-05-05
公開日2018-01-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献"Head-to-Middle" and "Head-to-Tail" cis-Prenyl Transferases: Structure of Isosesquilavandulyl Diphosphate Synthase.
Angew. Chem. Int. Ed. Engl., 57, 2018
7CBZ
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Crystal structure of T2R-TTL-A31 complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[5-[4-[2-[4-(2-cyclopropylethanoyl)piperazin-1-yl]ethoxy]phenyl]pyridin-2-yl]-N-(phenylmethyl)ethanamide, CALCIUM ION, ...
著者Yang, J.H, Yan, W.
登録日2020-06-15
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Design, Synthesis, and Bioactivity Evaluation of Dual-Target Inhibitors of Tubulin and Src Kinase Guided by Crystal Structure.
J.Med.Chem., 64, 2021
5XTQ
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Crystal structure of baculoviral sulfhydryl oxidase P33 (H227D mutant)
分子名称: FAD-linked sulfhydryl oxidase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Kuang, W, Hu, Z, Gong, P.
登録日2017-06-20
公開日2017-09-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Three Conserved Regions in Baculovirus Sulfhydryl Oxidase P33 Are Critical for Enzymatic Activity and Function
J. Virol., 91, 2017
5XUO
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Pks13 AT domain fragment from Mycobacterium tuberculosis
分子名称: Polyketide synthase Pks13
著者Yu, M.J, Gu, Y.J, Dou, C, Cheng, W.
登録日2017-06-24
公開日2018-05-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.586 Å)
主引用文献Crystallization and structure analysis of the core motif of the Pks13 acyltransferase domain fromMycobacterium tuberculosis
PeerJ, 6, 2018
5X4F
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Solution Structure of the N-terminal Domain of TDP-43
分子名称: TAR DNA-binding protein 43
著者Jiang, L.-L, Xue, W, Hu, H.-Y.
登録日2017-02-13
公開日2017-08-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The N-terminal dimerization is required for TDP-43 splicing activity.
Sci Rep, 7, 2017
5Y2V
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Strcutrue of the full-length CcmR complexed with 2-OG from Synechocystis PCC6803
分子名称: 2-OXOGLUTARIC ACID, PHOSPHATE ION, Rubisco operon transcriptional regulator
著者Jiang, Y.L, Wang, X.P, Sun, H, Cheng, W, Han, S.J, Li, W.F, Chen, Y, Zhou, C.Z.
登録日2017-07-27
公開日2017-12-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5Y2B
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Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with HEPTA-N-ACETYLCHITOOCTAOSE (NAG)7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase
著者Chen, W, Qu, M.B, Zhou, Y, Yang, Q.
登録日2017-07-24
公開日2018-01-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects
J. Biol. Chem., 293, 2018
5Y2C
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Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 2 E2180L mutant in complex with PENTA-N-ACETYLCHITOOCTAOSE (NAG)5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase
著者Chen, W, Qu, M.B, Zhou, Y, Yang, Q.
登録日2017-07-24
公開日2018-01-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects
J. Biol. Chem., 293, 2018
5Y2W
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Structure of Synechocystis PCC6803 CcmR regulatory domain in complex with 2-PG
分子名称: 2-PHOSPHOGLYCOLIC ACID, Rubisco operon transcriptional regulator
著者Jiang, Y.L, Wang, X.P, Sun, H, Cheng, W, Cao, D.D, Han, S.J, Li, W.F, Chen, Y, Zhou, C.Z.
登録日2017-07-27
公開日2017-12-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YFP
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Cryo-EM Structure of the Exocyst Complex
分子名称: Exocyst complex component EXO70, Exocyst complex component EXO84, Exocyst complex component SEC10, ...
著者Mei, K, Li, Y, Wang, S, Shao, G, Wang, J, Ding, Y, Luo, G, Yue, P, Liu, J.J, Wang, X, Dong, M.Q, Guo, W, Wang, H.W.
登録日2017-09-21
公開日2018-01-31
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Cryo-EM structure of the exocyst complex
Nat. Struct. Mol. Biol., 25, 2018
7D0P
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Crystal structure of human HBO1-BRPF2 in complex with propionyl-coenzyme A
分子名称: BRD1 protein, CHLORIDE ION, Histone acetyltransferase KAT7, ...
著者Li, W, Ding, J.
登録日2020-09-11
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献HBO1 is a versatile histone acyltransferase critical for promoter histone acylations.
Nucleic Acids Res., 49, 2021
7D0Q
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Crystal structure of human HBO1-BRPF2 in complex with butyryl-coenzyme A
分子名称: 1,2-ETHANEDIOL, BRD1 protein, Butyryl Coenzyme A, ...
著者Li, W, Ding, J.
登録日2020-09-11
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献HBO1 is a versatile histone acyltransferase critical for promoter histone acylations.
Nucleic Acids Res., 49, 2021
7D0O
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Crystal structure of human HBO1-BRPF2 in apo form
分子名称: 1,2-ETHANEDIOL, BRD1 protein, Histone acetyltransferase KAT7, ...
著者Li, W, Ding, J.
登録日2020-09-11
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献HBO1 is a versatile histone acyltransferase critical for promoter histone acylations.
Nucleic Acids Res., 49, 2021
7D0S
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Crystal structure of human HBO1-BRPF2 in complex with succinyl-coenzyme A
分子名称: BRD1 protein, Histone acetyltransferase KAT7, SUCCINYL-COENZYME A, ...
著者Li, W, Ding, J.
登録日2020-09-11
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献HBO1 is a versatile histone acyltransferase critical for promoter histone acylations.
Nucleic Acids Res., 49, 2021
7D0R
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Crystal structure of human HBO1-BRPF2 in complex with crotonoyl-coenzyme A
分子名称: 1,2-ETHANEDIOL, BRD1 protein, CROTONYL COENZYME A, ...
著者Li, W, Ding, J.
登録日2020-09-11
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献HBO1 is a versatile histone acyltransferase critical for promoter histone acylations.
Nucleic Acids Res., 49, 2021
5YAZ
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Crystal structure of the ANKRD domain of KANK1
分子名称: ACETATE ION, KN motif and ankyrin repeat domains 1
著者Wei, Z, Pan, W.
登録日2017-09-02
公開日2017-12-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into ankyrin repeat-mediated recognition of the kinesin motor protein KIF21A by KANK1, a scaffold protein in focal adhesion.
J. Biol. Chem., 293, 2018
5EW3
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Human Vascular Endothelial Growth Factor Receptor 2 (KDR) Kinase Domain in complex with AAL993
分子名称: 2-(pyridin-4-ylmethylamino)-~{N}-[3-(trifluoromethyl)phenyl]benzamide, Vascular endothelial growth factor receptor 2
著者Stark, W, Goepfert, A.
登録日2015-11-20
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Novel Potent Oral Series of VEGFR2 Inhibitors Abrogate Tumor Growth by Inhibiting Angiogenesis.
J.Med.Chem., 59, 2016
5Y9J
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BAFF in complex with belimumab
分子名称: Tumor necrosis factor ligand superfamily member 13B, belibumab light chain, belimumab heavy chain
著者Heo, Y.-S, Shin, W.
登録日2017-08-25
公開日2018-02-21
最終更新日2019-09-04
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus.
Nat Commun, 9, 2018
5YEU
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Structural and mechanistic analyses reveal a unique Cas4-like protein in the mimivirus virophage resistance element system
分子名称: MAGNESIUM ION, Uncharacterized protein R354
著者Dou, C, Yu, M.J, Gu, Y.J, Cheng, W.
登録日2017-09-19
公開日2018-07-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献Structural and Mechanistic Analyses Reveal a Unique Cas4-like Protein in the Mimivirus Virophage Resistance Element System.
Iscience, 3, 2018
5YF8
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Crystals structure of Classical swine fever virus NS5B (residues 1-672, Y471A-E472A mutant)
分子名称: ACETATE ION, RdRp catalytic
著者Liu, W, Gong, P.
登録日2017-09-20
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.396 Å)
主引用文献A unique intra-molecular fidelity-modulating mechanism identified in a viral RNA-dependent RNA polymerase.
Nucleic Acids Res., 46, 2018
5Y2A
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Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 2
分子名称: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase
著者Chen, W, Qu, M.B, Zhou, Y, Yang, Q.
登録日2017-07-24
公開日2018-01-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects
J. Biol. Chem., 293, 2018
5Y15
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Crystal structure of human DUSP28
分子名称: Dual specificity phosphatase 28, PHOSPHATE ION
著者Ku, B, Hong, W, Kim, S.J, Ryu, S.E.
登録日2017-07-19
公開日2017-11-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28
PLoS ONE, 12, 2017
5Y4C
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Crystal structure of EfeO-like protein Algp7 in complex with a metal ion
分子名称: Alginate-binding protein, COPPER (II) ION, GLYCEROL
著者Temtrirath, K, Maruyama, Y, Mikami, B, Murata, K, Hashimoto, W.
登録日2017-08-03
公開日2017-10-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Binding mode of metal ions to the bacterial iron import protein EfeO
Biochem. Biophys. Res. Commun., 493, 2017
5Y4M
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Discoidin domain of human CASPR2
分子名称: 1,2-ETHANEDIOL, human CASPR2 Disc domain
著者Liu, H, Xu, F, Zhang, J, Liang, W.
登録日2017-08-04
公開日2018-08-08
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Structural mapping of hot spots within human CASPR2 discoidin domain for autoantibody recognition.
J. Autoimmun., 96, 2019

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