1C10
 
 | | CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER PRESSURE OF XENON (8 BAR) | | 分子名称: | CHLORIDE ION, PROTEIN (LYSOZYME), SODIUM ION, ... | | 著者 | Prange, T, Schiltz, M, Pernot, L, Colloc'h, N, Longhi, S, Bourguet, W, Fourme, R. | | 登録日 | 1999-07-16 | | 公開日 | 1999-07-22 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Exploring hydrophobic sites in proteins with xenon or krypton.
Proteins, 30, 1998
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1BTE
 | | CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF THE TYPE II ACTIVIN RECEPTOR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (ACTIVIN RECEPTOR TYPE II) | | 著者 | Greenwald, J, Fischer, W, Vale, W, Choe, S. | | 登録日 | 1998-09-01 | | 公開日 | 1999-02-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Three-finger toxin fold for the extracellular ligand-binding domain of the type II activin receptor serine kinase.
Nat.Struct.Biol., 6, 1999
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1BKN
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1BUV
 | | CRYSTAL STRUCTURE OF THE MT1-MMP-TIMP-2 COMPLEX | | 分子名称: | CALCIUM ION, PROTEIN (MEMBRANE-TYPE MATRIX METALLOPROTEINASE (CDMT1-MMP)), PROTEIN (METALLOPROTEINASE INHIBITOR (TIMP-2)), ... | | 著者 | Fernandez-Catalan, C, Bode, W, Huber, R, Turk, D, Calvete, J.J, Lichte, A, Tschesche, H, Maskos, K. | | 登録日 | 1998-09-07 | | 公開日 | 1999-09-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor.
EMBO J., 17, 1998
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1BQY
 | | Plasminogen activator (TSV-PA) from snake venom | | 分子名称: | L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide, PLASMINOGEN ACTIVATOR | | 著者 | Parry, M.A.A, Bode, W. | | 登録日 | 1998-08-20 | | 公開日 | 1999-08-20 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structure of the novel snake venom plasminogen activator TSV-PA: a prototype structure for snake venom serine proteinases.
Structure, 6, 1998
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2BNZ
 | | Structural basis for cooperative binding of Ribbon-Helix-Helix Omega repressor to inverted DNA heptad repeats | | 分子名称: | 5'-D(*CP*TP*AP*AP*TP*CP*AP*CP*TP*TP *GP*TP*GP*AP*TP*TP*CP*G)-3', 5'-D(*GP*AP*AP*TP*CP*AP*CP*AP*AP*GP *TP*GP*AP*TP*TP*AP*GP*C)-3', ORF OMEGA | | 著者 | Weihofen, W.A, Cicek, A, Pratto, F, Alonso, J.C, Saenger, W. | | 登録日 | 2005-04-06 | | 公開日 | 2006-03-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription.
Nucleic Acids Res., 34, 2006
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1BKC
 | | CATALYTIC DOMAIN OF TNF-ALPHA CONVERTING ENZYME (TACE) | | 分子名称: | N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide, TUMOR NECROSIS FACTOR-ALPHA-CONVERTING ENZYME, ZINC ION | | 著者 | Maskos, K, Fernandez-Catalan, C, Bode, W. | | 登録日 | 1998-04-23 | | 公開日 | 1999-06-22 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.
Proc.Natl.Acad.Sci.USA, 95, 1998
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1BOE
 | | STRUCTURE OF THE IGF BINDING DOMAIN OF THE INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-5 (IGFBP-5): IMPLICATIONS FOR IGF AND IGF-I RECEPTOR INTERACTIONS | | 分子名称: | PROTEIN (INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-5 (IGFBP-5)) | | 著者 | Kalus, W, Zweckstetter, M, Renner, C, Sanchez, Y, Georgescu, J, Grol, M, Demuth, D, Schumacherdony, C, Lang, K, Holak, T.H. | | 登録日 | 1998-07-30 | | 公開日 | 1998-12-16 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions.
EMBO J., 17, 1998
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1BP3
 | | THE XRAY STRUCTURE OF A GROWTH HORMONE-PROLACTIN RECEPTOR COMPLEX | | 分子名称: | PROTEIN (GROWTH HORMONE), PROTEIN (PROLACTIN RECEPTOR), ZINC ION | | 著者 | Somers, W, Ultsch, M, De Vos, A.M, Kossiakoff, A.A. | | 登録日 | 1998-08-12 | | 公開日 | 1998-08-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The X-ray structure of a growth hormone-prolactin receptor complex.
Nature, 372, 1994
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2BJG
 | | Crystal Structure of Conjugated Bile Acid Hydrolase from Clostridium perfringens in Complex with Reaction Products Taurine and Deoxycholate | | 分子名称: | 1,2-ETHANEDIOL, CHOLOYLGLYCINE HYDROLASE | | 著者 | Rossocha, M, Schultz-Heienbrok, R, Von Moeller, H, Coleman, J.P, Saenger, W. | | 登録日 | 2005-02-02 | | 公開日 | 2005-05-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conjugated Bile Acid Hydrolase is a Tetrameric N-Terminal Thiol Hydrolase with Specific Recognition of its Cholyl But not of its Tauryl Product
Biochemistry, 44, 2005
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2WCP
 | | CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 | | 分子名称: | CADHERIN-23, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | | 登録日 | 2009-03-13 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural Determinants of Cadherin-23 Function in Hearing and Deafness.
Neuron, 66, 2010
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2WFH
 | | The Human Slit 2 Dimerization Domain D4 | | 分子名称: | SLIT HOMOLOG 2 PROTEIN C-PRODUCT, SULFATE ION | | 著者 | Seiradake, E, von Philipsborn, A.C, Henry, M, Fritz, M, Lortat-Jacob, H, Jamin, M, Hemrika, W, Bastmeyer, M, Cusack, S, McCarthy, A.A. | | 登録日 | 2009-04-06 | | 公開日 | 2009-04-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure and functional relevance of the Slit2 homodimerization domain.
EMBO Rep., 10, 2009
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1DZB
 | | Crystal structure of phage library-derived single-chain Fv fragment 1F9 in complex with turkey egg-white lysozyme | | 分子名称: | SCFV FRAGMENT 1F9, TURKEY EGG-WHITE LYSOZYME C | | 著者 | Ay, J, Keitel, T, Kuettner, G, Wessner, H, Scholz, C, Hahn, M, Hoehne, W. | | 登録日 | 2000-02-23 | | 公開日 | 2000-11-02 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of a Phage Library-Derived Single-Chain Fv Fragment Complexed with Turkey Egg -White Lysozyme at 2.0 A Resolution
J.Mol.Biol., 301, 2000
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2BQ2
 | | Solution Structure of the DNA Duplex ACGCGU-NA with a 2' Amido-Linked Nalidixic Acid Residue at the 3' Terminal Nucleotide | | 分子名称: | 5'-D(*AP*CP*GP*CP*GP*2AU)-3', NALIDIXIC ACID | | 著者 | Siegmund, K, Maheshwary, S, Narayanan, S, Connors, W, Richert, M. | | 登録日 | 2005-04-26 | | 公開日 | 2006-08-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular details of quinolone-DNA interactions: solution structure of an unusually stable DNA duplex with covalently linked nalidixic acid residues and non-covalent complexes derived from it.
Nucleic Acids Res., 33, 2005
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2BU6
 | | crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands | | 分子名称: | (N-{4-[(ETHYLANILINO)SULFONYL]-2-METHYLPHENYL}-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE, PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2 | | 著者 | Knoechel, T.R, Tucker, A.D, Robinson, C.M, Phillips, C, Taylor, W, Bungay, P.J, Kasten, S.A, Roche, T.E, Brown, D.G. | | 登録日 | 2005-06-08 | | 公開日 | 2006-02-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Regulatory Roles of the N-Terminal Domain Based on Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands.
Biochemistry, 45, 2006
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1DLR
 | | METHOTREXATE-RESISTANT VARIANTS OF HUMAN DIHYDROFOLATE REDUCTASE WITH SUBSTITUTION OF LEUCINE 22: KINETICS, CRYSTALLOGRAPHY AND POTENTIAL AS SELECTABLE MARKERS | | 分子名称: | 6-(2,5-DIMETHOXY-BENZYL)-5-METHYL-PYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINE, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W. | | 登録日 | 1995-01-25 | | 公開日 | 1995-04-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers.
J.Biol.Chem., 270, 1995
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1DAF
 | | DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, ADP, AND CALCIUM | | 分子名称: | 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | 著者 | Huang, W, Jia, J, Schneider, G, Lindqvist, Y. | | 登録日 | 1995-05-08 | | 公開日 | 1996-06-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
Biochemistry, 34, 1995
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1C25
 | | HUMAN CDC25A CATALYTIC DOMAIN | | 分子名称: | CDC25A | | 著者 | Fauman, E.B, Cogswell, J.P, Lovejoy, B, Rocque, W.J, Holmes, W, Montana, V.G, Piwnica-Worms, H, Rink, M.J, Saper, M.A. | | 登録日 | 1998-04-17 | | 公開日 | 1998-08-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A.
Cell(Cambridge,Mass.), 93, 1998
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1A0L
 | | HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE | | 分子名称: | (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid, BETA-TRYPTASE | | 著者 | Pereira, P.J.B, Bergner, A, Macedo-Ribeiro, S, Huber, R, Matschiner, G, Fritz, H, Sommerhoff, C.P, Bode, W. | | 登録日 | 1997-12-03 | | 公開日 | 1999-03-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.
Nature, 392, 1998
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1DAE
 | | DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 3-(1-AMINOETHYL) NONANEDIOIC ACID | | 分子名称: | 3-(1-AMINOETHYL)NONANEDIOIC ACID, DETHIOBIOTIN SYNTHETASE | | 著者 | Huang, W, Jia, J, Schneider, G, Lindqvist, Y. | | 登録日 | 1995-05-08 | | 公開日 | 1996-06-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
Biochemistry, 34, 1995
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1DLS
 | | METHOTREXATE-RESISTANT VARIANTS OF HUMAN DIHYDROFOLATE REDUCTASE WITH SUBSTITUTION OF LEUCINE 22: KINETICS, CRYSTALLOGRAPHY AND POTENTIAL AS SELECTABLE MARKERS | | 分子名称: | DIHYDROFOLATE REDUCTASE, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W. | | 登録日 | 1995-01-25 | | 公開日 | 1995-04-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers.
J.Biol.Chem., 270, 1995
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2WFE
 | | Structure of the Candida albicans cytosolic leucyl-tRNA synthetase editing domain | | 分子名称: | CYTOSOLIC LEUCYL-TRNA SYNTHETASE | | 著者 | Seiradake, E, Mao, W, Hernandez, V, Baker, S.J, Plattner, J.J, Alley, M.R.K, Cusack, S. | | 登録日 | 2009-04-04 | | 公開日 | 2009-05-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles.
J.Mol.Biol., 390, 2009
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2C1C
 | | Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors | | 分子名称: | CARBOXYPEPTIDASE B, YTTRIUM ION, ZINC ION | | 著者 | Bayes, A, Comellas-Bigler, M, Rodriguez de la Vega, M, Maskos, K, Bode, W, Aviles, F.X, Jongsma, M.A, Beekwilder, J, Vendrell, J. | | 登録日 | 2005-09-12 | | 公開日 | 2005-10-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis of the Resistance of an Insect Carboxypeptidase to Plant Protease Inhibitors.
Proc.Natl.Acad.Sci.USA, 102, 2005
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2WFG
 | | Structure of the Candida albicans cytosolic leucyl-tRNA synthetase editing domain bound to a benzoxaborole-AMP adduct | | 分子名称: | CYTOSOLIC LEUCYL-TRNA SYNTHETASE, [(1S,3S,5R,6R,8R)-6-(6-AMINOPURIN-9-YL)-4'-ETHYLAMINO-3'-FLUORO-SPIRO[2,4,7-TRIOXA-3-BORANUIDABICYCLO[3.3.0]OCTANE-3,7'-8-OXA-7-BORANUIDABICYCLO[4.3.0]NONA-1,3,5-TRIENE]-8-YL]METHYL DIHYDROGEN PHOSPHATE | | 著者 | Seiradake, E, Mao, W, Hernandez, V, Baker, S.J, Plattner, J.J, Alley, M.R.K, Cusack, S. | | 登録日 | 2009-04-05 | | 公開日 | 2009-05-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles.
J.Mol.Biol., 390, 2009
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2BU7
 | | crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands | | 分子名称: | N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE, PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2 | | 著者 | Knoechel, T.R, Tucker, A.D, Robinson, C.M, Phillips, C, Taylor, W, Bungay, P.J, Kasten, S.A, Roche, T.E, Brown, D.G. | | 登録日 | 2005-06-08 | | 公開日 | 2006-02-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Regulatory Roles of the N-Terminal Domain Based on Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands.
Biochemistry, 45, 2006
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