2WFE

Structure of the Candida albicans cytosolic leucyl-tRNA synthetase editing domain

Summary for 2WFE

Related2WFG
DescriptorCYTOSOLIC LEUCYL-TRNA SYNTHETASE (1 entity in total)
Functional Keywordsligase, leucyl-trna synthetase, editing domain, candida albicans, hydrolysis of mis-charged trnas
Biological sourceCANDIDA ALBICANS
Total number of polymer chains4
Total molecular weight117986.46
Authors
Seiradake, E.,Mao, W.,Hernandez, V.,Baker, S.J.,Plattner, J.J.,Alley, M.R.K.,Cusack, S. (deposition date: 2009-04-04, release date: 2009-05-19, Last modification date: 2011-07-13)
Primary citation
Seiradake, E.,Mao, W.,Hernandez, V.,Baker, S.J.,Plattner, J.J.,Alley, M.R.K.,Cusack, S.
Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles.
J.Mol.Biol., 390:196-, 2009
PubMed: 19426743 (PDB entries with the same primary citation)
DOI: 10.1016/J.JMB.2009.04.073
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.28950.2%4.4%2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution