1A0L
HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE
Summary for 1A0L
Entry DOI | 10.2210/pdb1a0l/pdb |
Descriptor | BETA-TRYPTASE, (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid (3 entities in total) |
Functional Keywords | trypsin-like serine proteinase, tetramer, heparin, allergy, asthma, serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P20231 |
Total number of polymer chains | 4 |
Total formula weight | 110410.10 |
Authors | Pereira, P.J.B.,Bergner, A.,Macedo-Ribeiro, S.,Huber, R.,Matschiner, G.,Fritz, H.,Sommerhoff, C.P.,Bode, W. (deposition date: 1997-12-03, release date: 1999-03-23, Last modification date: 2011-07-13) |
Primary citation | Pereira, P.J.,Bergner, A.,Macedo-Ribeiro, S.,Huber, R.,Matschiner, G.,Fritz, H.,Sommerhoff, C.P.,Bode, W. Human beta-tryptase is a ring-like tetramer with active sites facing a central pore. Nature, 392:306-311, 1998 Cited by PubMed: 9521329DOI: 10.1038/32703 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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