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PDB: 12380 件

2REO
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Crystal structure of human sulfotransferase 1C3 (Sult1C3) in complex with PAP
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Putative sulfotransferase 1C3
著者Tempel, W, Pan, P, Dong, A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2007-09-26
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.651 Å)
主引用文献Crystal structure of human sulfotransferase 1C3 (Sult1C3) in complex with PAP.
To be Published
2R9M
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BU of 2r9m by Molmil
Cathepsin S complexed with Compound 15
分子名称: Cathepsin S, N-[(1S)-2-[(4-cyano-1-methylpiperidin-4-yl)amino]-1-(cyclohexylmethyl)-2-oxoethyl]morpholine-4-carboxamide
著者Ward, Y.D, Emmanuel, M.J, Thomson, D.S, Liu, W, Bekkali, Y, Frye, L.L, Girardot, M, Morwick, T, Young, E.R.R, Zindell, R, Hrapchak, M, DeTuri, M, White, A, Crane, K.M, White, D.M, Wang, Y, Hao, M.-H, Grygon, C.A, Labadia, M.E, Wildeson, J, Freeman, D, Nelson, R, Capolino, A, Peterson, J.D, Raymond, E.L, Brown, M.L, Spero, D.M.
登録日2007-09-13
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Design and Synthesis of Reversible Inhibitors of Cathepsin S: alpha,alpha-Disubstitution at the P1 Residue Provides Potent Inhibitors in Cellular Assays and In Vivo Models of Antigen Presentation
To be Published
2RG2
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Crystal structure of variant R18L of conjugated bile acid hydrolase from Clostridium perfringens
分子名称: 1,2-ETHANEDIOL, Choloylglycine hydrolase, GLYCEROL, ...
著者Rossmann, M, Saenger, W.
登録日2007-10-02
公開日2009-02-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of variants of conjugated bile acid hydrolase from Clostridium perfringens
To be Published
6RBL
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BU of 6rbl by Molmil
TETR(D) E147A MUTANT IN COMPLEX WITH DOXYCYCLINE AND MAGNESIUM
分子名称: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
著者Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
登録日2019-04-10
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
8HP3
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Crystal structure of meso-diaminopimelate dehydrogenase from Prevotella timonensis
分子名称: 1,2-ETHANEDIOL, Meso-diaminopimelate D-dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Tan, Y, Song, W.
登録日2022-12-11
公開日2023-12-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Rational Design of Meso -Diaminopimelate Dehydrogenase with Enhanced Reductive Amination Activity for Efficient Production of d- p -Hydroxyphenylglycine.
Appl.Environ.Microbiol., 89, 2023
8HP0
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Crystal structure of meso-diaminopimelate dehydrogenase from Prevotella timonensis
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Meso-diaminopimelate D-dehydrogenase, SULFATE ION
著者Tan, Y, Song, W.
登録日2022-12-11
公開日2023-12-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Rational Design of Meso -Diaminopimelate Dehydrogenase with Enhanced Reductive Amination Activity for Efficient Production of d- p -Hydroxyphenylglycine.
Appl.Environ.Microbiol., 89, 2023
6RBM
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TETR(D) E147A MUTANT IN COMPLEX WITH MINOCYCLINE AND MAGNESIUM
分子名称: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
著者Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
登録日2019-04-11
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
6RCR
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BU of 6rcr by Molmil
TETR(D) H100A MUTANT IN COMPLEX WITH DOXYCYCLINE AND MAGNESIUM
分子名称: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
著者Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
登録日2019-04-11
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
6RKO
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BU of 6rko by Molmil
Cryo-EM structure of the E. coli cytochrome bd-I oxidase at 2.68 A resolution
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome bd-I ubiquinol oxidase subunit 1, ...
著者Safarian, S, Hahn, A, Kuehlbrandt, W, Michel, H.
登録日2019-04-30
公開日2019-10-16
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Active site rearrangement and structural divergence in prokaryotic respiratory oxidases.
Science, 366, 2019
8I7L
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BU of 8i7l by Molmil
Crystal structure of indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with a novel inhibitor
分子名称: 1-[3-[(4-chloranyl-2-fluoranyl-phenyl)carbamoylamino]-4-[cyclohexyl(2-methylpropyl)amino]phenyl]pyrrole-2-carboxylic acid, Indoleamine 2,3-dioxygenase 1, THIOSULFATE
著者Li, K, Liu, W, Dong, X.
登録日2023-02-01
公開日2023-02-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Apo-Form Selective Inhibition of IDO for Tumor Immunotherapy.
J Immunol., 209, 2022
6RZU
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BU of 6rzu by Molmil
Structure of s-Mgm1 decorating the outer surface of tubulated lipid membranes in the GTPgammaS bound state
分子名称: Putative mitochondrial dynamin protein
著者Faelber, K, Dietrich, L, Noel, J.K, Sanchez, R, Kudryashev, M, Kuelbrandt, W, Daumke, O.
登録日2019-06-13
公開日2019-07-24
最終更新日2020-11-18
実験手法ELECTRON MICROSCOPY (14.7 Å)
主引用文献Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1.
Nature, 571, 2019
4W2R
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BU of 4w2r by Molmil
Structure of Hs/AcPRC2 in complex with 5,8-dichloro-2-[(4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-7-[(R)-methoxy(oxetan-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one
分子名称: 5,8-dichloro-2-[(4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-7-[(R)-methoxy(oxetan-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one, Enhancer of zeste 2 polycomb repressive complex 2 subunit, Polycomb protein EED, ...
著者Gajiwala, K.S, Brooun, A, Liu, W, Deng, Y, Stewart, A.E.
登録日2017-09-25
公開日2017-12-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497).
J. Med. Chem., 61, 2018
4X36
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Crystal structure of the autolysin LytA from Streptococcus pneumoniae TIGR4
分子名称: Autolysin, CHOLINE ION, GLYCEROL, ...
著者Cheng, W, Li, Q, Zhou, C.Z, Chen, Y.X.
登録日2014-11-28
公開日2015-05-27
最終更新日2015-06-24
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Full-length structure of the major autolysin LytA.
Acta Crystallogr.,Sect.D, 71, 2015
4X0R
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Crystal structure of human MxB stalk domain
分子名称: Interferon-induced GTP-binding protein Mx2
著者Yu, X.-F, Xie, W.
登録日2014-11-23
公開日2014-12-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.905 Å)
主引用文献Structural insight into the assembly of human anti-HIV dynamin-like protein MxB/Mx2.
Biochem.Biophys.Res.Commun., 456, 2015
3KTT
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BU of 3ktt by Molmil
Atomic model of bovine TRiC CCT2(beta) subunit derived from a 4.0 Angstrom cryo-EM map
分子名称: T-complex protein 1 subunit beta
著者Cong, Y, Baker, M.L, Ludtke, S.J, Frydman, J, Chiu, W.
登録日2009-11-25
公開日2010-03-16
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement.
Proc.Natl.Acad.Sci.USA, 107, 2010
2FUZ
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UGL hexagonal crystal structure without glycine and DTT molecules
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Unsaturated glucuronyl hydrolase
著者Itoh, T, Hashimoto, W, Mikami, B, Murata, K.
登録日2006-01-28
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Substrate recognition by unsaturated glucuronyl hydrolase from Bacillus sp. GL1
Biochem.Biophys.Res.Commun., 344, 2006
2FV2
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Crystal Structure Analysis of human Rcd-1 conserved region
分子名称: MANGANESE (II) ION, RCD1 required for cell differentiation1 homolog
著者Garces, R.G, Gillon, W, Pai, E.F.
登録日2006-01-28
公開日2007-01-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Atomic model of human Rcd-1 reveals an armadillo-like-repeat protein with in vitro nucleic acid binding properties.
Protein Sci., 16, 2007
2FOL
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Crystal structure of human RAB1A in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-1A, ...
著者Wang, J, Tempel, W, Shen, Y, Shen, L, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2006-01-13
公開日2006-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.631 Å)
主引用文献Crystal structure of human RAB1A in complex with GDP
To be Published
2FQD
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Crystal Structures of E. coli Laccase CueO under different copper binding situations
分子名称: Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ...
著者Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W.
登録日2006-01-18
公開日2007-01-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of E. coli laccase CueO at different copper concentrations.
Biochem.Biophys.Res.Commun., 354, 2007
2G1D
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Solution Structure of Ribosomal Protein S24E from Thermoplasma acidophilum
分子名称: 30S ribosomal protein S24e
著者Jeon, B.-Y, Hong, E.-M, Jung, J.-W, Yee, A, Arrowsmith, C.H, Lee, W.
登録日2006-02-14
公開日2007-02-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of TA1092, a ribosomal protein S24e from Thermoplasma acidophilum
Proteins, 64, 2006
4N9L
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crystal structure of beta-lactamse PenP_E166S in complex with meropenem
分子名称: (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Beta-lactamase
著者Pan, X, Wong, W, Zhao, Y.
登録日2013-10-21
公開日2014-09-10
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation
Biochemistry, 53, 2014
2FXO
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Structure of the human beta-myosin S2 fragment
分子名称: Myosin heavy chain, cardiac muscle beta isoform
著者Blankenfeldt, W, Thoma, N.H, Wray, J.S, Gautel, M, Schlichting, I.
登録日2006-02-06
公開日2006-11-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of human cardiac {beta}-myosin II S2-{Delta} provide insight into the functional role of the S2 subfragment
Proc.Natl.Acad.Sci.Usa, 103, 2006
2FZF
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Hypothetical Protein Pfu-1136390-001 From Pyrococcus furiosus
分子名称: hypothetical protein
著者Fu, Z.-Q, Liu, Z.-J, Lee, D, Kelley, L, Chen, L, Tempel, W, Shah, N, Horanyi, P, Lee, H.S, Habel, J, Dillard, B.D, Nguyen, D, Chang, S.-H, Zhang, H, Chang, J, Sugar, F.J, Poole, F.L, Jenney Jr, F.E, Adams, M.W.W, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2006-02-09
公開日2006-02-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Hypothetical Protein Pfu-1136390-001 From Pyrococcus furiosus
To be published
2G25
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E. Coli Pyruvate Dehydrogenase Phosphonolactylthiamin Diphosphate Complex
分子名称: 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, MAGNESIUM ION, PHOSPHATE ION, ...
著者Furey, W, Arjunan, P, Chandrasekhar, K.
登録日2006-02-15
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Thiamin-bound, Pre-decarboxylation Reaction Intermediate Analogue in the Pyruvate Dehydrogenase E1 Subunit Induces Large Scale Disorder-to-Order Transformations in the Enzyme and Reveals Novel Structural Features in the Covalently Bound Adduct.
J.Biol.Chem., 281, 2006
2G3K
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Crystal structure of the C-terminal domain of Vps28
分子名称: Vacuolar protein sorting-associated protein VPS28
著者Pineda-Molina, E, Belrhali, H, Piefer, A.J, Akula, I, Bates, P, Weissenhorn, W.
登録日2006-02-20
公開日2006-06-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献The crystal structure of the C-terminal domain of Vps28 reveals a conserved surface required for Vps20 recruitment.
Traffic, 7, 2006

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