5XNX

Crystallographic structure of the enzymatically active N-terminal domain of the Rel protein from Mycobacterium tuberculosis

Summary for 5XNX

• Entry DOI: 10.2210/pdb5xnx/pdb
• Descriptor: Bifunctional (p)ppGpp synthase/hydrolase RelA, MAGNESIUM ION (2 entities in total)
• Functional Keywords: rela, mycobacterium tuberculosis, hd domain, hydrolase, helix bundle, synthetase domain, (p)ppgpp, stringent response, transferase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Total number of polymer chains: 4
• Total formula weight: 178677.67

Authors

Singal, B.,Balakrishna, A.M.,Manimekalai, M.S.S.,Nartey, W.,Gruber, G. (deposition date: 2017-05-24, release date: 2017-07-19, Last modification date: 2023-11-22)

• Primary citation: Singal, B.,Balakrishna, A.M.,Nartey, W.,Manimekalai, M.S.S.,Jeyakanthan, J.,Gruber, G.; Crystallographic and solution structure of the N-terminal domain of the Rel protein from Mycobacterium tuberculosis; FEBS Lett., 591:2323-2337, 2017; PubMed: 28672070; DOI: 10.1002/1873-3468.12739

Experimental method

X-RAY DIFFRACTION (3.7 Å)