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PDB: 12479 件

2YJ2
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CATHEPSIN L WITH A NITRILE INHIBITOR
分子名称: (2S,4R)-1-[1-(4-BROMOPHENYL)CYCLOPROPYL]CARBONYL-4-(2-CHLOROPHENYL)SULFONYL-N-[1-(IMINOMETHYL)CYCLOPROPYL]PYRROLIDINE-2-CARBOXAMIDE, CATHEPSIN L1, GLYCEROL
著者Banner, D.W, Benz, J.M, Haap, W.
登録日2011-05-18
公開日2011-11-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
Chemmedchem, 6, 2011
2YQE
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Solution structure of the ARID domain of JARID1D protein
分子名称: Jumonji/ARID domain-containing protein 1D
著者Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-30
公開日2008-04-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the ARID domain of JARID1D protein
To be Published
2YT7
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Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3
分子名称: Amyloid beta A4 precursor protein-binding family A member 3
著者Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Seiki, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2008-04-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3
To be Published
2YGN
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WIF domain of human Wnt inhibitory factor 1 in complex with 1,2- dipalmitoylphosphatidylcholine
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Malinauskas, T, Aricescu, A.R, Lu, W, Siebold, C, Jones, E.Y.
登録日2011-04-19
公開日2011-07-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Modular Mechanism of Wnt Signaling Inhibition by Wnt Inhibitory Factor 1
Nat.Struct.Mol.Biol., 18, 2011
2YJQ
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Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CEL44C, ...
著者Ariza, A, Eklof, J.M, Spadiut, O, Offen, W.A, Roberts, S.M, Besenmatter, W, Friis, E.P, Skjot, M, Wilson, K.S, Brumer, H, Davies, G.
登録日2011-05-23
公開日2011-06-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure and Activity of Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44.
J.Biol.Chem., 286, 2011
6OGY
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In situ structure of Rotavirus RNA-dependent RNA polymerase at duplex-open state
分子名称: DNA/RNA (5'-D(*(GTG))-R(P*GP*C)-3'), Inner capsid protein VP2, RNA (5'-R(P*AP*GP*CP*C)-3'), ...
著者Ding, K, Chang, T, Shen, W, Roy, P, Zhou, Z.H.
登録日2019-04-03
公開日2019-05-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release.
Nat Commun, 10, 2019
2YR0
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Crystal Structure of Hypothetical Methyltransferase TTHA0223 from Thermus thermophilus HB8
分子名称: Hypothetical protein TTHA0223
著者Kagawa, W, Kurumizaka, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-01
公開日2007-10-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Hypothetical Methyltransferase TTHA0223 from Thermus thermophilus HB8
To be published
2YBV
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STRUCTURE OF RUBISCO FROM THERMOSYNECHOCOCCUS ELONGATUS
分子名称: CHLORIDE ION, RIBULOSE BISPHOSPHATE CARBOXYLASE LARGE CHAIN, RIBULOSE BISPHOSPHATE CARBOXYLASE SMALL SUBUNIT
著者Terlecka, B, Wilhelmi, V, Bialek, W, Gubernator, B, Szczepaniak, A, Hofmann, E.
登録日2011-03-10
公開日2012-03-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of Ribulose-1,5-Bisphosphate Carboxylase Oxygenase from Thermosynechococcus Elongatus
To be Published
4X8D
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Ergothioneine-biosynthetic sulfoxide synthase EgtB in complex with N,N-dimethyl-histidine and gamma-glutamyl-cysteine
分子名称: CALCIUM ION, CHLORIDE ION, GAMMA-GLUTAMYLCYSTEINE, ...
著者Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P.
登録日2014-12-10
公開日2015-01-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway.
Angew.Chem.Int.Ed.Engl., 54, 2015
6OJN
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Comparative Model of SGIV Major Coat Protein (MCP) Trimer Based on Cryo-EM Map
分子名称: Major capsid protein
著者Pintilie, G, Chen, D.-H, Tran, B.N, Jakana, J, Wu, J, Hew, C.L, Chiu, W.
登録日2019-04-11
公開日2019-06-12
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献Segmentation and Comparative Modeling in an 8.6- angstrom Cryo-EM Map of the Singapore Grouper Iridovirus.
Structure, 27, 2019
4WW5
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Crystal structure of binary complex Bud32-Cgi121 in complex with AMPP
分子名称: ACETATE ION, EKC/KEOPS complex subunit BUD32, EKC/KEOPS complex subunit CGI121, ...
著者Zhang, W.
登録日2014-11-10
公開日2015-03-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Nucleic Acids Res., 43, 2015
4WW9
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Crystal structure of binary complex Bud32-Cgi121 in complex with ADP
分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, EKC/KEOPS complex subunit BUD32, ...
著者Zhang, W, Van Tilbeurgh, H.
登録日2014-11-10
公開日2015-03-18
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.951 Å)
主引用文献Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Nucleic Acids Res., 43, 2015
2YXQ
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The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal
分子名称: Preprotein translocase secG subunit, Preprotein translocase subunit secE, Preprotein translocase subunit secY
著者Li, W, Schulman, S.
登録日2007-04-27
公開日2007-08-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal
Mol.Cell, 26, 2007
4WYU
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Crystal Structure of Scribble PDZ34 tandem in complex with its target peptide
分子名称: IODIDE ION, Protein scribble homolog, peptide SER-TRP-PHE-GLN-THR-ASP-LEU
著者Ren, J.Q, Pei, H.H, Feng, W.
登録日2014-11-18
公開日2015-10-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule.
Biochem.J., 468, 2015
1OJH
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Crystal structure of NblA from PCC 7120
分子名称: 1,2-ETHANEDIOL, NBLA
著者Bienert, R, Baier, K, Lockau, W, Heinemann, U.
登録日2003-07-10
公開日2004-07-15
最終更新日2011-08-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Nbla from Anabaena Sp. Pcc 7120, a Small Protein Playing a Key Role in Phycobilisome Degradation.
J.Biol.Chem., 281, 2006
6OLF
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Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OFB
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Crystal structure of human glutamine-dependent NAD+ synthetase complexed with NaAD+, AMP, pyrophosphate, and Mg2+
分子名称: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Glutamine-dependent NAD(+) synthetase, ...
著者Chuenchor, W, Doukov, T.I, Gerratana, B.
登録日2019-03-28
公開日2020-01-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Different ways to transport ammonia in human and Mycobacterium tuberculosis NAD+synthetases.
Nat Commun, 11, 2020
4X3X
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The crystal structure of Arc C-lobe
分子名称: Activity-regulated cytoskeleton-associated protein
著者Zhang, W, Ward, M, Leahy, D, Worley, P.
登録日2014-12-01
公開日2015-06-03
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of arc binding to synaptic proteins: implications for cognitive disease.
Neuron, 86, 2015
6E31
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Crystal structure of RIAM in an autoinhibited configuration.
分子名称: Rap1-interacting adapter molecule
著者Chang, Y.C, Su, W, Zhang, H, Huang, Q, Philips, M.R, Wu, J.
登録日2018-07-12
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6OM0
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Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-17
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6EHM
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Model of the Ebola virus nucleocapsid subunit from recombinant virus-like particles
分子名称: Membrane-associated protein VP24, Nucleoprotein
著者Wan, W, Kolesnikova, L, Clarke, M, Koehler, A, Noda, T, Becker, S, Briggs, J.A.G.
登録日2017-09-13
公開日2017-11-08
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structure and assembly of the Ebola virus nucleocapsid.
Nature, 551, 2017
2Z42
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Crystal Structure of Family 7 Alginate Lyase A1-II' from Sphingomonas sp. A1
分子名称: Alginate lyase, SULFATE ION
著者Ogura, K, Yamasaki, M, Hashimoto, W, Mikami, B, Murata, K.
登録日2007-06-12
公開日2008-05-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Substrate Recognition by Family 7 Alginagte Lyase from Sphingomonas sp. A1
To be published
4X1G
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Crystal structure of the hPXR-LBD in complex with the synthetic estrogen 17alpha-ethinylestradiol and the pesticide trans-nonachlor
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Ethinyl estradiol, ISOPROPYL ALCOHOL, ...
著者Delfosse, V, Huet, T, Bourguet, W.
登録日2014-11-24
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds.
Nat Commun, 6, 2015
1P6I
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Rat neuronal NOS heme domain with (4S)-N-(4-amino-5-[aminoethyl]aminopentyl)-N'-nitroguanidine bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(4S)-4-AMINO-5-[(2-AMINOETHYL)AMINO]PENTYL}-N'-NITROGUANIDINE, ...
著者Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
6OC9
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S8 phosphorylated beta amyloid 40 fibrils
分子名称: Amyloid-beta precursor protein, PHOSPHONATE
著者Qiang, W, Hu, Z.W.
登録日2019-03-22
公開日2019-06-05
最終更新日2024-05-01
実験手法SOLID-STATE NMR
主引用文献Molecular structure of an N-terminal phosphorylated beta-amyloid fibril.
Proc.Natl.Acad.Sci.USA, 116, 2019

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件を2024-07-10に公開中

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