6OFB

Crystal structure of human glutamine-dependent NAD+ synthetase complexed with NaAD+, AMP, pyrophosphate, and Mg2+

Summary for 6OFB

Entry DOI	10.2210/pdb6ofb/pdb
Related	6OFC
Descriptor	Glutamine-dependent NAD(+) synthetase, NICOTINIC ACID ADENINE DINUCLEOTIDE, ADENOSINE MONOPHOSPHATE, ... (7 entities in total)
Functional Keywords	ligase, glutamine-amido transferase, gat, nad+ synthetase, glutamine-dependent nad+ synthetase, nad synthetase 1, glutaminase, ammonia tunneling, enzyme, atp-binding, nucleotide-binding
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	161708.32
Authors	Chuenchor, W.,Doukov, T.I.,Gerratana, B. (deposition date: 2019-03-28, release date: 2020-01-08, Last modification date: 2023-10-25)
Primary citation	Chuenchor, W.,Doukov, T.I.,Chang, K.T.,Resto, M.,Yun, C.S.,Gerratana, B. Different ways to transport ammonia in human and Mycobacterium tuberculosis NAD+synthetases. Nat Commun, 11:16-16, 2020 Cited by PubMed: 31911602 DOI: 10.1038/s41467-019-13845-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.84 Å)

Structure validation