6OFB
Crystal structure of human glutamine-dependent NAD+ synthetase complexed with NaAD+, AMP, pyrophosphate, and Mg2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamine-dependent NAD(+) synthetase | polymer | 707 | 79481.7 | 2 | UniProt (Q6IA69) Pfam (PF00795) Pfam (PF02540) | Homo sapiens (Human) | NAD(+) synthase [glutamine-hydrolyzing],NAD(+) synthetase |
| 2 | C, L (A, B) | NICOTINIC ACID ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 2 | Chemie (DND) | |||
| 3 | D, M (A, B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 4 | E, N (A, B) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 2 | Chemie (POP) | |||
| 5 | F, O (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | G, H, I, J, K... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 9 | Chemie (CL) | |||
| 7 | T, U (A, B) | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 706 (UniProt: Q6IA69)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Leu 74 | Val 74 | variant |
| His 204 | Gln 204 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 158963.4 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2744.9 | |
| All* | Total formula weight | 161708.3 |
