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PDB: 12479 件

2H3M
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Crystal Structure of ZO-1 PDZ1
分子名称: SULFATE ION, Tight junction protein ZO-1
著者Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C.
登録日2006-05-22
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.
J.Biol.Chem., 281, 2006
2LN8
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The solution structure of theromacin
分子名称: Theromacin
著者Jung, S, Soennichsen, F.D, Hung, C.-W, Tholey, A, Boidin-Wichlacz, C, Hausgen, W, Gelhaus, C, Desel, C, Podschun, R, Watzig, V, Tasiemski, A, Leippe, M, Groetzinger, J.
登録日2011-12-20
公開日2012-03-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Macin family of antimicrobial proteins combines antimicrobial and nerve repair activities.
J.Biol.Chem., 287, 2012
2L6S
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Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide
分子名称: VIR-576
著者Forssmann, W, The, Y, Stoll, M, Adermann, K, Albrecht, U, Barlos, K, Busmann, A, Canales-Mayordomo, A, Gimenez-Gallego, G, Hirsch, J, Jimenez-Barbero, J, Meyer-Olson, D, Muench, J, Perez-Castells, J, Standker, L, Kirchhoff, F, Schmidt, R.E.
登録日2010-11-24
公開日2011-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide.
Sci Transl Med, 2, 2010
2JAE
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The structure of L-amino acid oxidase from Rhodococcus opacus in the unbound state
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, L-AMINO ACID OXIDASE
著者Faust, A, Niefind, K, Hummel, W, Schomburg, D.
登録日2006-11-27
公開日2007-01-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The Structure of a Bacterial L-Amino Acid Oxidase from Rhodococcus Opacus Gives New Evidence for the Hydride Mechanism for Dehydrogenation.
J.Mol.Biol., 367, 2007
2K2G
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Solution structure of the wild-type catalytic domain of human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor
分子名称: Macrophage metalloelastase, N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine, ZINC ION
著者Markus, M.A, Dwyer, B, Wolfrom, S, Li, J, Li, W, Malakian, K, Wilhelm, J, Tsao, D.H.H.
登録日2008-04-01
公開日2008-05-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of wild-type human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor.
J.Biomol.Nmr, 41, 2008
2L6T
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Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide
分子名称: VIR-576
著者Forssmann, W, The, Y, Stoll, M, Adermann, K, Albrecht, U, Barlos, K, Busmann, A, Can les-Mayordomo, A, Gimenez-Gallego, G, Hirsch, J, Jimenez-Barbero, J, Meyer-Olson, D, Muench, J, Perez-Castells, J, Staendker, L, Kirchhoff, F, Schmidt, R.E.
登録日2010-11-24
公開日2011-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide.
Sci Transl Med, 2, 2010
2L4O
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Solution structure of the Streptococcus pneumoniae RrgB pilus backbone D1 domain
分子名称: Cell wall surface anchor family protein
著者Gentile, M.A, Melchiorre, S, Emolo, C, Moschioni, M, Gianfaldoni, C, Pancotto, L, Ferlenghi, I, Scarselli, M, Pansegrau, W, Veggi, D, Merola, M, Cantini, F, Ruggiero, P, Banci, L, Masignani, V.
登録日2010-10-11
公開日2011-03-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the Streptococcus pneumoniae RrgB pilus backbone D1 domain: in vivo protection and implications for the molecular mechanisms of pilus polymerization
To be Published
2YVA
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Crystal structure of Escherichia coli DiaA
分子名称: DnaA initiator-associating protein diaA
著者Keyamura, K, Fujikawa, N, Ishida, T, Ozaki, S, Suetsugu, M, Kagawa, W, Yokoyama, S, Kurumizaka, H, Katayama, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-10
公開日2008-01-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The interaction of DiaA and DnaA regulates the replication cycle in E. coli by directly promoting ATP DnaA-specific initiation complexes
Genes Dev., 21, 2007
6DKA
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Yeast Ddi2 Cyanamide Hydratase
分子名称: CYANAMIDE, DNA damage-inducible protein, SULFATE ION, ...
著者Moore, S.A, Xiao, W, Li, J.
登録日2018-05-29
公開日2019-05-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Structure of Ddi2, a highly inducible detoxifying metalloenzyme fromSaccharomyces cerevisiae.
J.Biol.Chem., 294, 2019
6NR8
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hTRiC-hPFD Class6
分子名称: Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ...
著者Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J.
登録日2019-01-23
公開日2019-06-19
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019
6DOM
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Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 50 mM K+ for 120 s at 21 C
分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ...
著者Samara, N.L, Yang, W.
登録日2018-06-09
公開日2018-08-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.425 Å)
主引用文献Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
6DP2
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Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 7.5 mM Mg2+ and 75 mM K+ for 40 s at 21 C
分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', ...
著者Samara, N.L, Yang, W.
登録日2018-06-09
公開日2018-08-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.662 Å)
主引用文献Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
6DPO
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Crystal Structure of Bacillus Halodurans Ribonuclease H1 E188A in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 360 s at 21 C
分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ...
著者Samara, N.L, Yang, W.
登録日2018-06-09
公開日2018-08-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
6O0R
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BU of 6o0r by Molmil
Crystal structure of the TIR domain from human SARM1 in complex with glycerol
分子名称: GLYCEROL, Sterile alpha and TIR motif-containing protein 1
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Deerain, N, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6DVB
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Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 5nt spacer
分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Lin, W, Das, K, Feng, Y, Ebright, R.H.
登録日2018-06-23
公開日2019-02-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
2YD8
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Crystal structure of the N-terminal Ig1-2 module of Human Receptor Protein Tyrosine Phosphatase LAR in complex with sucrose octasulphate
分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F
著者Coles, C.H, Shen, Y, Tenney, A.P, Siebold, C, Sutton, G.C, Lu, W, Gallagher, J.T, Jones, E.Y, Flanagan, J.G, Aricescu, A.R.
登録日2011-03-18
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension.
Science, 332, 2011
6NWQ
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Chronic traumatic encephalopathy Type II Tau filament
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zivanov, J, Zhang, W, Murzin, A.G, Garringer, H.J, Vidal, R, Crowther, R.A, Newell, K.L, Ghetti, B, Goedert, M, Scheres, H.W.
登録日2019-02-07
公開日2019-03-27
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.
Nature, 568, 2019
2YR1
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Crystal Structure of 3-dehydroquinate dehydratase from Geobacillus kaustophilus HTA426
分子名称: 3-dehydroquinate dehydratase
著者Kagawa, W, Kurumizaka, H, Bessho, Y, Chen, L, Fu, Z.Q, Chrzas, J, Wang, B.C, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-01
公開日2007-10-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of 3-dehydroquinate dehydratase from Geobacillus kaustophilus HTA426
To be published
6NVY
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Crystal structure of penicillin G acylase from Bacillus thermotolerans
分子名称: CALCIUM ION, GLYCEROL, Penicillin G acylase
著者Blankenfeldt, W.
登録日2019-02-05
公開日2019-07-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal structures and protein engineering of three different penicillin G acylases from Gram-positive bacteria with different thermostability.
Appl.Microbiol.Biotechnol., 103, 2019
6NYL
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BU of 6nyl by Molmil
Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2c (OA-2c)
分子名称: Vacuolating cytotoxin autotransporter
著者Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W.
登録日2019-02-11
公開日2019-03-27
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
4V07
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Dimeric pseudorabies virus protease pUL26N at 2.1 A resolution
分子名称: CHLORIDE ION, MAGNESIUM ION, UL26
著者Zuehlsdorf, M, Werten, S, Palm, G.J, Hinrichs, W.
登録日2014-09-11
公開日2015-07-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin Pul26N, a Herpesvirus Serine Protease
Plos Pathog., 11, 2015
6O0U
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BU of 6o0u by Molmil
Crystal structure of the TIR domain H685A mutant from human SARM1
分子名称: Sterile alpha and TIR motif-containing protein 1
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6DO8
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BU of 6do8 by Molmil
Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 80 s at 21 C
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ...
著者Samara, N.L, Yang, W.
登録日2018-06-09
公開日2018-08-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.414 Å)
主引用文献Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
6O0Q
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Crystal structure of the TIR domain from human SARM1 in complex with ribose
分子名称: CHLORIDE ION, Sterile alpha and TIR motif-containing protein 1, beta-D-ribofuranose
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Deerain, N, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6DOE
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Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 420 s at 21 C
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ...
著者Samara, N.L, Yang, W.
登録日2018-06-09
公開日2018-08-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018

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