2YD8

Crystal structure of the N-terminal Ig1-2 module of Human Receptor Protein Tyrosine Phosphatase LAR in complex with sucrose octasulphate

Summary for 2YD8

Entry DOI	10.2210/pdb2yd8/pdb
Related	2YD1 2YD2 2YD3 2YD4 2YD5 2YD6 2YD7 2YD9
Descriptor	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose (3 entities in total)
Functional Keywords	hydrolase, rptpf
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Membrane; Single-pass type I membrane protein: P10586
Total number of polymer chains	1
Total formula weight	23880.71
Authors	Coles, C.H.,Shen, Y.,Tenney, A.P.,Siebold, C.,Sutton, G.C.,Lu, W.,Gallagher, J.T.,Jones, E.Y.,Flanagan, J.G.,Aricescu, A.R. (deposition date: 2011-03-18, release date: 2011-04-13, Last modification date: 2023-12-20)
Primary citation	Coles, C.H.,Shen, Y.,Tenney, A.P.,Siebold, C.,Sutton, G.C.,Lu, W.,Gallagher, J.T.,Jones, E.Y.,Flanagan, J.G.,Aricescu, A.R. Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension. Science, 332:484-, 2011 Cited by PubMed: 21454754 DOI: 10.1126/SCIENCE.1200840 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation