6LDE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lde by Molmil](/molmil-images/mine/6lde) | |
6LDG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ldg by Molmil](/molmil-images/mine/6ldg) | |
6L7I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l7i by Molmil](/molmil-images/mine/6l7i) | |
6L8R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l8r by Molmil](/molmil-images/mine/6l8r) | membrane-bound PD-L1-CD | Descriptor: | Programmed cell death 1 ligand 1 | Authors: | Maorong, W, Cao, Y, Bin, W, Bo, O. | Deposit date: | 2019-11-07 | Release date: | 2020-11-11 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain. Nat Commun, 12, 2021
|
|
5WOL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wol by Molmil](/molmil-images/mine/5wol) | Crystal structure of dihydrodipicolinate reductase DapB from Coxiella burnetii | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, 4-hydroxy-tetrahydrodipicolinate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Stogios, P.J, Wawrzak, Z, Onopriyenko, O, Grimshaw, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-08-02 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of dihydrodipicolinate reductase DapB from Coxiella burnetii To Be Published
|
|
6M0S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m0s by Molmil](/molmil-images/mine/6m0s) | 3.6A Yeast Vo state3 prime | Descriptor: | Uncharacterized protein YPR170W-B, V-type proton ATPase subunit a, vacuolar isoform, ... | Authors: | Roh, S.H, Shekhar, M, Pintilie, G, Chipot, C, Wilkens, S, SIngharoy, A, Chiu, W. | Deposit date: | 2020-02-22 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V o complex. Sci Adv, 6, 2020
|
|
6M7F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m7f by Molmil](/molmil-images/mine/6m7f) | Wild-type Cucumene Synthase | Descriptor: | Cucumene Synthase | Authors: | Blank, P.N, Pemberton, T.A, Christianson, D.W. | Deposit date: | 2018-08-20 | Release date: | 2018-10-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.051 Å) | Cite: | Crystal Structure of Cucumene Synthase, a Terpenoid Cyclase That Generates a Linear Triquinane Sesquiterpene. Biochemistry, 57, 2018
|
|
6M7V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m7v by Molmil](/molmil-images/mine/6m7v) | Human DNA polymerase eta extension complex with cdA at the -1 position | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(P*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(P*GP*TP*GP*TP*GP*AP*GP*T)-3'), ... | Authors: | Weng, P, Gao, Y, Yang, W. | Deposit date: | 2018-08-21 | Release date: | 2018-09-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.062 Å) | Cite: | Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6LQI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lqi by Molmil](/molmil-images/mine/6lqi) | Cryo-EM structure of the mouse Piezo1 isoform Piezo1.1 | Descriptor: | Piezo-type mechanosensitive ion channel component 1 | Authors: | Geng, J, Liu, W, Zhou, H, Zhang, T, Wang, L, Zhang, M, Shen, B, Li, X, Xiao, B. | Deposit date: | 2020-01-13 | Release date: | 2020-03-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel. Neuron, 106, 2020
|
|
6LMU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lmu by Molmil](/molmil-images/mine/6lmu) | Cryo-EM structure of the human CALHM2 | Descriptor: | Calcium homeostasis modulator protein 2 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
|
|
6LPB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lpb by Molmil](/molmil-images/mine/6lpb) | Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Kobayashi, K, Shihoya, W, Nishizawa, T, Nureki, O. | Deposit date: | 2020-01-09 | Release date: | 2020-03-11 | Last modified: | 2020-03-25 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein. Nat.Struct.Mol.Biol., 27, 2020
|
|
6LMX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lmx by Molmil](/molmil-images/mine/6lmx) | Cryo-EM structure of the CALHM chimeric construct (9-mer) | Descriptor: | Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
|
|
6LZL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lzl by Molmil](/molmil-images/mine/6lzl) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with Piperine | Descriptor: | (2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Liu, Z.H, Wu, D, Lu, W.Q, Huang, J. | Deposit date: | 2020-02-19 | Release date: | 2020-04-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with Piperine To Be Published
|
|
6M7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m7o by Molmil](/molmil-images/mine/6m7o) | Human DNA polymerase eta ternary complex with Mn2+ and dTMPNPP oppositing cdA | Descriptor: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*AP*TP*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(P*AP*GP*TP*GP*TP*GP*AP*G*(1FZ))-3'), ... | Authors: | Weng, P, Gao, Y, Yang, W. | Deposit date: | 2018-08-20 | Release date: | 2018-09-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6M8Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m8z by Molmil](/molmil-images/mine/6m8z) | Crystal structure of human DJ-1 without a modification on Cys-106 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Protein/nucleic acid deglycase DJ-1 | Authors: | Shumilin, I.A, Shabalin, I.G, Shumilina, S.V, Werenskjold, C, Utepbergenov, D, Minor, W. | Deposit date: | 2018-08-22 | Release date: | 2018-09-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | A transient post-translational modification of active site cysteine alters binding properties of the parkinsonism protein DJ-1. Biochem. Biophys. Res. Commun., 504, 2018
|
|
6LMV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lmv by Molmil](/molmil-images/mine/6lmv) | Cryo-EM structure of the C. elegans CLHM-1 | Descriptor: | Calcium homeostasis modulator protein | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
|
|
6LRY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lry by Molmil](/molmil-images/mine/6lry) | Crystal structure of human endothelin ETB receptor in complex with sarafotoxin S6b | Descriptor: | Endothelin receptor type B,Endolysin,Endothelin receptor type B, Sarafotoxin-B | Authors: | Izume, T, Miyauchi, H, Shihoya, W, Nureki, O. | Deposit date: | 2020-01-16 | Release date: | 2020-02-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of human endothelin ETBreceptor in complex with sarafotoxin S6b. Biochem.Biophys.Res.Commun., 528, 2020
|
|
6LSQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lsq by Molmil](/molmil-images/mine/6lsq) | |
6MAF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6maf by Molmil](/molmil-images/mine/6maf) | native BbvCI A2B2 tetramer at low resolution | Descriptor: | BbvCI endonuclease subunit 1, BbvCI endonuclease subunit 2 | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2018-08-27 | Release date: | 2018-11-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.79 Å) | Cite: | Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI. Nucleic Acids Res., 47, 2019
|
|
6M0W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m0w by Molmil](/molmil-images/mine/6m0w) | Crystal structure of Streptococcus thermophilus Cas9 in complex with the AGAA PAM | Descriptor: | CRISPR-associated endonuclease Cas9 1, DNA (28-MER), DNA (5'-D(*AP*AP*AP*GP*AP*AP*GP*C)-3'), ... | Authors: | Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q. | Deposit date: | 2020-02-23 | Release date: | 2020-09-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Catalytic-state structure and engineering of Streptococcus thermophilus Cas9 Nat Catal, 2020
|
|
6M5Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m5q by Molmil](/molmil-images/mine/6m5q) | A class C beta-lactamase mutant - Y150F | Descriptor: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, Beta-lactamase | Authors: | Bae, D.W, Jung, Y.E, Cha, S.S. | Deposit date: | 2020-03-11 | Release date: | 2021-01-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Novel inhibition mechanism of carbapenems on the ACC-1 class C beta-lactamase. Arch.Biochem.Biophys., 693, 2020
|
|
6LMW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lmw by Molmil](/molmil-images/mine/6lmw) | Cryo-EM structure of the CALHM chimeric construct (8-mer) | Descriptor: | Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
|
|
6LNB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lnb by Molmil](/molmil-images/mine/6lnb) | CryoEM structure of Cascade-TniQ-dsDNA complex | Descriptor: | CRISPR RNA (60-MER), CRISPR-associated protein Cas6, CRISPR-associated protein Cas7, ... | Authors: | Wang, B, Xu, W, Yang, H. | Deposit date: | 2019-12-28 | Release date: | 2020-02-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Structural basis of a Tn7-like transposase recruitment and DNA loading to CRISPR-Cas surveillance complex. Cell Res., 30, 2020
|
|
6MF5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mf5 by Molmil](/molmil-images/mine/6mf5) | |
6M2V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m2v by Molmil](/molmil-images/mine/6m2v) | Crystal structure of UHRF1 SRA complexed with fully-mCHG DNA. | Descriptor: | DNA (5'-D(*TP*CP*AP*CP*GP*(5CM)P*TP*GP*CP*GP*TP*GP*A)-3'), E3 ubiquitin-protein ligase UHRF1 | Authors: | Abhishek, S, Nakarakanti, N.K, Deeksha, W, Rajakumara, E. | Deposit date: | 2020-03-01 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanistic insights into recognition of symmetric methylated cytosines in CpG and non-CpG DNA by UHRF1 SRA. Int.J.Biol.Macromol., 170, 2021
|
|