6M8Z

Crystal structure of human DJ-1 without a modification on Cys-106

Summary for 6M8Z

Entry DOI	10.2210/pdb6m8z/pdb
Related	6E5Z
Descriptor	Protein/nucleic acid deglycase DJ-1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	the exact function of this protein is still unknown, unknown function
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	20318.94
Authors	Shumilin, I.A.,Shabalin, I.G.,Shumilina, S.V.,Werenskjold, C.,Utepbergenov, D.,Minor, W. (deposition date: 2018-08-22, release date: 2018-09-05, Last modification date: 2023-10-11)
Primary citation	Mussakhmetov, A.,Shumilin, I.A.,Nugmanova, R.,Shabalin, I.G.,Baizhumanov, T.,Toibazar, D.,Khassenov, B.,Minor, W.,Utepbergenov, D. A transient post-translational modification of active site cysteine alters binding properties of the parkinsonism protein DJ-1. Biochem. Biophys. Res. Commun., 504:328-333, 2018 Cited by PubMed: 30190129 DOI: 10.1016/j.bbrc.2018.08.190 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.83 Å)

Structure validation