6XOI
| Structure of SUMO1-ML00752641 adduct bound to SAE | 分子名称: | SULFATE ION, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ... | 著者 | Sintchak, M, Lane, W, Bump, N. | 登録日 | 2020-07-07 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. J.Med.Chem., 64, 2021
|
|
5MPS
| Structure of a spliceosome remodeled for exon ligation | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | 登録日 | 2016-12-18 | 公開日 | 2017-01-18 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | 主引用文献 | Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
|
|
6XFI
| Crystal Structures of beta-1,4-N-Acetylglucosaminyltransferase 2 (POMGNT2): Structural Basis for Inherited Muscular Dystrophies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, ... | 著者 | Halmo, S.M, Yeh, J, Wells, L, Moremen, K.W, Lanzilotta, W.N. | 登録日 | 2020-06-15 | 公開日 | 2021-04-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of beta-1,4-N-acetylglucosaminyltransferase 2: structural basis for inherited muscular dystrophies. Acta Crystallogr D Struct Biol, 77, 2021
|
|
1LNE
| A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN | 分子名称: | CADMIUM ION, CALCIUM ION, DIMETHYL SULFOXIDE, ... | 著者 | Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W. | 登録日 | 1994-05-13 | 公開日 | 1995-05-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995
|
|
5DEB
| |
6XRZ
| The 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome | 分子名称: | Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome | 著者 | Zhang, K, Zheludev, I, Hagey, R, Wu, M, Haslecker, R, Hou, Y, Kretsch, R, Pintilie, G, Rangan, R, Kladwang, W, Li, S, Pham, E, Souibgui, C, Baric, R, Sheahan, T, Souza, V, Glenn, J, Chiu, W, Das, R. | 登録日 | 2020-07-14 | 公開日 | 2020-08-19 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome. Biorxiv, 2020
|
|
3BJX
| |
5D2O
| 2009 H1N1 PA endonuclease mutant F105S | 分子名称: | MANGANESE (II) ION, Polymerase acidic protein | 著者 | Kumar, G, White, S.W. | 登録日 | 2015-08-05 | 公開日 | 2016-03-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
6XOW
| |
8BG9
| Murine amyloid-beta filaments with the Arctic mutation (E22G) from APP(NL-G-F) mouse brains | ABeta | 分子名称: | Amyloid-beta protein 40 | 著者 | Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W. | 登録日 | 2022-10-27 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains. Acta Neuropathol, 145, 2023
|
|
8BG0
| Amyloid-beta tetrameric filaments with the Arctic mutation (E22G) from Alzheimer's disease brains | ABeta40 | 分子名称: | Amyloid-beta precursor protein | 著者 | Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W. | 登録日 | 2022-10-27 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (1.99 Å) | 主引用文献 | Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains. Acta Neuropathol, 145, 2023
|
|
8BFZ
| Amyloid-beta 42 filaments extracted from the human brain with Arctic mutation (E22G) of Alzheimer's disease | ABeta42 | 分子名称: | Amyloid-beta precursor protein | 著者 | Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordberg, A, Goedert, M, Scheres, S.H.W. | 登録日 | 2022-10-27 | 公開日 | 2023-01-18 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains. Acta Neuropathol, 145, 2023
|
|
8OT2
| Structural and functional studies of geldanamycin amide synthase ShGdmF | 分子名称: | 1,2-ETHANEDIOL, 3-azanyl-5-methyl-phenol, ACETATE ION, ... | 著者 | Ewert, W, Zeilinger, C, Kirschning, A, Preller, M. | 登録日 | 2023-04-20 | 公開日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural and functional studies of geldanamycin amide synthase ShGdmF To Be Published
|
|
6IS7
| Structure of 9N-I DNA polymerase incorporation with dA in the active site | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*CP*TP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*A)-3'), ... | 著者 | Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H. | 登録日 | 2018-11-15 | 公開日 | 2019-08-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing. Commun Biol, 2, 2019
|
|
1XG7
| Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus | 分子名称: | hypothetical protein | 著者 | Chang, J, Zhao, M, Horanyi, P, Xu, H, Yang, H, Liu, Z.-J, Chen, L, Zhou, W, Habel, J, Tempel, W, Lee, D, Lin, D, Chang, S.-H, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.-S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Chen, C.-Y, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Adams, M.W.W, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-09-16 | 公開日 | 2004-11-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus To be published
|
|
5K53
| |
6WLU
| V. cholerae glycine riboswitch with glycine models, 5.7 Angstrom resolution | 分子名称: | RNA (231-MER) | 著者 | Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R. | 登録日 | 2020-04-20 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | 主引用文献 | Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures. Nat.Methods, 17, 2020
|
|
6OS3
| Crystal structure of native CymD prenyltransferase | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CymD prenyltransferase | 著者 | Roose, B.W, Christianson, D.W. | 登録日 | 2019-05-01 | 公開日 | 2019-07-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis of Tryptophan Reverse N-Prenylation Catalyzed by CymD. Biochemistry, 58, 2019
|
|
1VPR
| |
4Z40
| Active site complex BamBC of Benzoyl Coenzyme A reductase as isolated | 分子名称: | Benzoyl-CoA reductase, putative, IRON/SULFUR CLUSTER, ... | 著者 | Weinert, T, Kung, J.W, Weidenweber, S, Huwiler, S.G, Boll, M, Ermler, U. | 登録日 | 2015-04-01 | 公開日 | 2015-06-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural basis of enzymatic benzene ring reduction. Nat.Chem.Biol., 11, 2015
|
|
6ZTH
| |
6ZTI
| |
1XI3
| Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001 | 分子名称: | NICKEL (II) ION, SULFATE ION, Thiamine phosphate pyrophosphorylase, ... | 著者 | Zhou, W, Chen, L, Tempel, W, Liu, Z.-J, Habel, J, Lee, D, Lin, D, Chang, S.-H, Dillard, B.D, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Kelley, L.-L.C, Lee, H.-S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Adams, M.W.W, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-09-21 | 公開日 | 2004-09-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001 To be published
|
|
8K1T
| Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of MgCl2 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | 著者 | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | 登録日 | 2023-07-11 | 公開日 | 2024-04-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | 主引用文献 | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB. Nat Commun, 15, 2024
|
|
8K1S
| Potassium transporter KtrAB from Bacillus subtilis in ADP-bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | 著者 | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | 登録日 | 2023-07-11 | 公開日 | 2024-04-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB. Nat Commun, 15, 2024
|
|