6OS3

Crystal structure of native CymD prenyltransferase

Summary for 6OS3

DescriptorCymD prenyltransferase, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywordsprenyltransferase, tryptophan, indole, biosynthesis, transferase
Biological sourceSalinispora arenicola (strain CNS-205)
Total number of polymer chains2
Total molecular weight82815.47
Authors
Roose, B.W.,Christianson, D.W. (deposition date: 2019-05-01, release date: 2019-07-17, Last modification date: 2019-08-14)
Primary citation
Roose, B.W.,Christianson, D.W.
Structural Basis of Tryptophan Reverse N-Prenylation Catalyzed by CymD.
Biochemistry, 58:3232-3242, 2019
PubMed: 31251043 (PDB entries with the same primary citation)
DOI: 10.1021/acs.biochem.9b00399
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20860 1.2% 1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution