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PDB: 21 results

6QCL
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BU of 6qcl by Molmil
Citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase in complex with acetyl-CoA and L-malate
Descriptor: (2S)-2-hydroxybutanedioic acid, ACETYL COENZYME *A, ATP-citrate lyase alpha-subunit, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-12-28
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6QFB
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BU of 6qfb by Molmil
Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, CITRATE ANION, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2019-01-09
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXN
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BU of 6hxn by Molmil
Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P3121)
Descriptor: ATP-citrate lyase alpha-subunit, COENZYME A, SULFATE ION
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXQ
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BU of 6hxq by Molmil
Structure of citryl-CoA synthetase from Hydrogenobacter thermophilus
Descriptor: CITRATE ANION, COENZYME A, Citryl-CoA synthetase large subunit, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXK
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BU of 6hxk by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate
Descriptor: 1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXM
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BU of 6hxm by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH in space group C2221
Descriptor: ATP-citrate synthase, CITRATE ANION, COENZYME A
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6GLX
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BU of 6glx by Molmil
Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 4E8
Descriptor: Fab 4E8 - Heavy chain, Fab 4E8 - Light chain, Galectin-10
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-23
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.396 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GKU
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BU of 6gku by Molmil
Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 6F5
Descriptor: CALCIUM ION, Fab 6F5 - Heavy Chain, Fab 6F5 - Light chain, ...
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-21
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GLW
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BU of 6glw by Molmil
Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 1D11
Descriptor: ACETATE ION, Fab 1D11 - Heavy chain, Fab 1D11 - Light chain, ...
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-23
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GKQ
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BU of 6gkq by Molmil
X-ray structure determined from ex vivo Charcot-Leyden crystal
Descriptor: GLYCEROL, Galectin-10
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-21
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GKS
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BU of 6gks by Molmil
X-ray structure determined from recombinant Charcot-Leyden crystal
Descriptor: GLYCEROL, Galectin-10
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-21
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GKT
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BU of 6gkt by Molmil
X-ray structure of a non-autocrystallizing galectin-10 variant, Gal10-Tyr69Glu
Descriptor: Galectin-10, HEXAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ...
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-21
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
7Z3Q
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BU of 7z3q by Molmil
Crystal structure of the human leptin:LepR-CRH2 encounter complex to 3.6 A resolution.
Descriptor: Leptin, Leptin receptor
Authors:Verstraete, K, Verschueren, K, Alexandra, T, Savvides, S.N.
Deposit date:2022-03-02
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.617 Å)
Cite:Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
7Z3R
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BU of 7z3r by Molmil
Crystal structure of the mouse leptin:LepR-IgCRH2 complex to 2.95 A resolution.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
Authors:Verstraete, K, Verschueren, K, Savvides, S.N, Tsirigotaki, A.
Deposit date:2022-03-02
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.951 Å)
Cite:Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
7Z3P
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BU of 7z3p by Molmil
Crystal structure of the mouse leptin:LepR-CRH2 encounter complex to 1.95 A resolution.
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Leptin, ...
Authors:Tsirigotaki, A, Verschueren, K, Savvides, S.N, Verstraete, K.
Deposit date:2022-03-02
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.943 Å)
Cite:Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
6HXH
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BU of 6hxh by Molmil
Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase,Human ATP citrate lyase, CITRATE ANION, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXI
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BU of 6hxi by Molmil
Structure of ATP citrate lyase from Methanothrix soehngenii in complex with citrate and coenzyme A
Descriptor: ACETATE ION, CITRATE ANION, COENZYME A, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXL
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BU of 6hxl by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH (space group P21)
Descriptor: 1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXO
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BU of 6hxo by Molmil
Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P21)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ATP-citrate lyase alpha-subunit, CITRATE ANION
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXJ
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BU of 6hxj by Molmil
Structure of ATP citrate lyase from Chlorobium limicola in complex with citrate and coenzyme A.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-citrate lyase alpha-subunit, ATP-citrate lyase beta-subunit, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXP
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BU of 6hxp by Molmil
Structure of citryl-CoA lyase from Hydrogenobacter thermophilus
Descriptor: COENZYME A, Citryl-CoA lyase, SULFATE ION
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019

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