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PDB: 143 件
8SES
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BU of 8ses by Molmil
Cryo-EM Structure of RyR1 + Adenine
分子名称: ADENINE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.98 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEO
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BU of 8seo by Molmil
Cryo-EM Structure of RyR1 + ATP-gamma-S
分子名称: Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEQ
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BU of 8seq by Molmil
Cryo-EM Structure of RyR1 + AMP
分子名称: ADENOSINE MONOPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SET
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BU of 8set by Molmil
Cryo-EM Structure of RyR1 + cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8F5B
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BU of 8f5b by Molmil
Human ABCA4 structure in complex with AMP-PNP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Scortecci, J.F, Van Petegem, F, Molday, R.S.
登録日2022-11-13
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Structural and Functional Characterization of ABCA4 in its Nucleotide-Bound State
To Be Published
8SEW
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BU of 8sew by Molmil
Cryo-EM Structure of RyR1 + ADP (Local Refinement of TMD)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEX
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BU of 8sex by Molmil
Cryo-EM Structure of RyR1 + AMP (Local Refinement of TMD)
分子名称: ADENOSINE MONOPHOSPHATE, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SF0
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BU of 8sf0 by Molmil
Cryo-EM Structure of RyR1 + cAMP (Local Refinement of TMD)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEZ
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BU of 8sez by Molmil
Cryo-EM Structure of RyR1 + Adenine (Local Refinement of TMD)
分子名称: ADENINE, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEV
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BU of 8sev by Molmil
Cryo-EM Structure of RyR1 + ATP-gamma-S (Local Refinement of TMD)
分子名称: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEY
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BU of 8sey by Molmil
Cryo-EM Structure of RyR1 + Adenosine (Local Refinement of TMD)
分子名称: ADENOSINE, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEU
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BU of 8seu by Molmil
Cryo-EM Structure of RyR1 (Local Refinement of TMD)
分子名称: Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
5SV8
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BU of 5sv8 by Molmil
Crystal Structure of the catalytic nucleophile and surface cysteine mutant of VvEG16 in complex with a xyloglucan oligosaccharide
分子名称: alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, probable xyloglucan endotransglucosylase/hydrolase protein 19
著者McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H.
登録日2016-08-05
公開日2016-09-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.588 Å)
主引用文献Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases.
Plant J., 89, 2017
5C33
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BU of 5c33 by Molmil
Crystal Structure of Mouse Ryanodine Receptor 2 SPRY1 Domain
分子名称: CHLORIDE ION, ISOPROPYL ALCOHOL, Ryanodine receptor 2
著者Yuchi, Z, Van Petegem, F.
登録日2015-06-16
公開日2015-08-05
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant.
Nat Commun, 6, 2015
5C30
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BU of 5c30 by Molmil
Crystal Structure of Rabbit Ryanodine Receptor 1 Repeat12 Domain
分子名称: ISOPROPYL ALCOHOL, Ryanodine receptor 1
著者Yuchi, Z, Van Petegem, F.
登録日2015-06-16
公開日2015-08-05
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant.
Nat Commun, 6, 2015
2XOA
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BU of 2xoa by Molmil
Crystal Structure of the N-terminal three domains of the skeletal muscle Ryanodine Receptor (RyR1)
分子名称: RYANODINE RECEPTOR 1
著者Tung, C, Lobo, P.A, Kimlicka, L, Van Petegem, F.
登録日2010-08-10
公開日2010-11-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Amino-Terminal Disease Hotspot of Ryanodine Receptors Forms a Cytoplasmic Vestibule.
Nature, 468, 2010
7RXE
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BU of 7rxe by Molmil
Crystal structure of junctophilin-2
分子名称: CITRATE ANION, ISOPROPYL ALCOHOL, Junctophilin-2 N-terminal fragment
著者Yang, Z, Panwar, P, Van Petegem, F.
登録日2021-08-22
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.
Proc.Natl.Acad.Sci.USA, 119, 2022
6PAL
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BU of 6pal by Molmil
Bacteroides uniformis endo-laminarinase BuGH158 from the beta(1,3)-glucan utilization locus
分子名称: ACETATE ION, SULFATE ION, Uncharacterized protein
著者Tamura, K, Brumer, H, van Petegem, F.
登録日2019-06-11
公開日2020-04-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.818 Å)
主引用文献Synergy between Cell Surface Glycosidases and Glycan-Binding Proteins Dictates the Utilization of Specific Beta(1,3)-Glucans by Human GutBacteroides.
Mbio, 11, 2020
1PG5
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BU of 1pg5 by Molmil
CRYSTAL STRUCTURE OF THE UNLIGATED (T-STATE) ASPARTATE TRANSCARBAMOYLASE FROM THE EXTREMELY THERMOPHILIC ARCHAEON SULFOLOBUS ACIDOCALDARIUS
分子名称: Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ZINC ION
著者De Vos, D, Van Petegem, F, Remaut, H, Legrain, C, Glansdorff, N, Van Beeumen, J.J.
登録日2003-05-27
公開日2004-06-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of T State Aspartate Carbamoyltransferase of the Hyperthermophilic Archaeon Sulfolobus acidocaldarius.
J.Mol.Biol., 339, 2004
7RW4
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BU of 7rw4 by Molmil
Crystal structure of junctophilin-1
分子名称: ACETATE ION, GLYCEROL, Junctophilin-1
著者Yang, Z, Panwar, P, Van Petegem, F.
登録日2021-08-19
公開日2022-02-23
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.
Proc.Natl.Acad.Sci.USA, 119, 2022
3OXQ
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BU of 3oxq by Molmil
Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Kim, E.Y, Rumpf, C.H, Van Petegem, F, Arant, R, Findeisen, F, Cooley, E.S, Isacoff, E.Y, Minor, D.L.
登録日2010-09-21
公開日2010-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization.
Embo J., 29, 2010
7RXQ
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BU of 7rxq by Molmil
Crystal structure of junctophilin-2 in complex with a CaV1.1 peptide
分子名称: ETHANOL, Junctophilin-2 N-terminal fragment, SULFATE ION, ...
著者Yang, Z, Panwar, P, Van Petegem, F.
登録日2021-08-23
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.
Proc.Natl.Acad.Sci.USA, 119, 2022
5KHG
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BU of 5khg by Molmil
HCN2 CNBD in complex with cytidine-3', 5'-cyclic monophosphate (cCMP)
分子名称: 4-amino-1-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]pyrimidin-2(1H)-one, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
著者Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A.
登録日2016-06-14
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.241 Å)
主引用文献Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
1H71
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BU of 1h71 by Molmil
Psychrophilic Protease from Pseudoalteromonas 'TAC II 18'
分子名称: CALCIUM ION, SERRALYSIN, ZINC ION
著者Villeret, V, Van Petegem, F, Aghajari, N, Chessa, J.-P, Gerday, C, Haser, R, Van Beeumen, J.
登録日2001-07-02
公開日2003-02-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of a Psychrophilic Metalloprotease Reveal New Insights Into Catalysis by Cold-Adapted Proteases
Proteins: Struct.,Funct., Genet., 50, 2003
6VSV
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BU of 6vsv by Molmil
Crystal structure of a disease mutant of the Voltage-gated Sodium Channel Beta 4 subunit extracellular domain
分子名称: Sodium channel subunit beta-4
著者Das, S, Van Petegem, F.
登録日2020-02-12
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Biophysical Investigation of Sodium Channel Interaction with beta-Subunit Variants Associated with Arrhythmias.
Bioelectricity, 2, 2020

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件を2024-05-29に公開中

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