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PDB: 143 件
8F5B
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BU of 8f5b by Molmil
Human ABCA4 structure in complex with AMP-PNP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Scortecci, J.F, Van Petegem, F, Molday, R.S.
登録日2022-11-13
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Structural and Functional Characterization of ABCA4 in its Nucleotide-Bound State
To Be Published
7TCI
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BU of 7tci by Molmil
Structure of Xenopus KCNQ1-CaM in complex with ML277
分子名称: (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide, CALCIUM ION, Calmodulin-1, ...
著者Willegems, K, Kyriakis, E, Van Petegem, F, Eldstrom, J, Fedida, D.
登録日2021-12-23
公開日2022-07-06
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277.
Nat Commun, 13, 2022
7TCP
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BU of 7tcp by Molmil
Structure of Xenopus KCNQ1-CaM
分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1
著者Willegems, K, Kyriakis, E, Van Petegem, F, Eldstrom, J, Fedida, D.
登録日2021-12-27
公開日2022-07-06
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277.
Nat Commun, 13, 2022
1PG5
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BU of 1pg5 by Molmil
CRYSTAL STRUCTURE OF THE UNLIGATED (T-STATE) ASPARTATE TRANSCARBAMOYLASE FROM THE EXTREMELY THERMOPHILIC ARCHAEON SULFOLOBUS ACIDOCALDARIUS
分子名称: Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ZINC ION
著者De Vos, D, Van Petegem, F, Remaut, H, Legrain, C, Glansdorff, N, Van Beeumen, J.J.
登録日2003-05-27
公開日2004-06-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of T State Aspartate Carbamoyltransferase of the Hyperthermophilic Archaeon Sulfolobus acidocaldarius.
J.Mol.Biol., 339, 2004
7CF9
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BU of 7cf9 by Molmil
Structure of RyR1 (Ca2+/CHL)
分子名称: 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z.
登録日2020-06-24
公開日2020-09-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural basis for diamide modulation of ryanodine receptor.
Nat.Chem.Biol., 16, 2020
8SER
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BU of 8ser by Molmil
Cryo-EM Structure of RyR1 + Adenosine
分子名称: ADENOSINE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEP
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Cryo-EM Structure of RyR1 + ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEQ
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BU of 8seq by Molmil
Cryo-EM Structure of RyR1 + AMP
分子名称: ADENOSINE MONOPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SES
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BU of 8ses by Molmil
Cryo-EM Structure of RyR1 + Adenine
分子名称: ADENINE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.98 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SET
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Cryo-EM Structure of RyR1 + cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEO
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BU of 8seo by Molmil
Cryo-EM Structure of RyR1 + ATP-gamma-S
分子名称: Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEN
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BU of 8sen by Molmil
Cryo-EM Structure of RyR1
分子名称: Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEU
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BU of 8seu by Molmil
Cryo-EM Structure of RyR1 (Local Refinement of TMD)
分子名称: Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEV
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BU of 8sev by Molmil
Cryo-EM Structure of RyR1 + ATP-gamma-S (Local Refinement of TMD)
分子名称: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEY
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BU of 8sey by Molmil
Cryo-EM Structure of RyR1 + Adenosine (Local Refinement of TMD)
分子名称: ADENOSINE, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEW
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BU of 8sew by Molmil
Cryo-EM Structure of RyR1 + ADP (Local Refinement of TMD)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SF0
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BU of 8sf0 by Molmil
Cryo-EM Structure of RyR1 + cAMP (Local Refinement of TMD)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEZ
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BU of 8sez by Molmil
Cryo-EM Structure of RyR1 + Adenine (Local Refinement of TMD)
分子名称: ADENINE, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEX
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BU of 8sex by Molmil
Cryo-EM Structure of RyR1 + AMP (Local Refinement of TMD)
分子名称: ADENOSINE MONOPHOSPHATE, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
6Y4P
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BU of 6y4p by Molmil
Calmodulin N53I variant bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain
分子名称: CALCIUM ION, Calmodulin-1, Ryanodine receptor 2
著者Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R.
登録日2020-02-21
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.13325572 Å)
主引用文献The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
6Y4O
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BU of 6y4o by Molmil
Calmodulin bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain
分子名称: CALCIUM ION, Calmodulin-2, Ryanodine receptor 2
著者Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R.
登録日2020-02-21
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.83549082 Å)
主引用文献The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
1H71
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Psychrophilic Protease from Pseudoalteromonas 'TAC II 18'
分子名称: CALCIUM ION, SERRALYSIN, ZINC ION
著者Villeret, V, Van Petegem, F, Aghajari, N, Chessa, J.-P, Gerday, C, Haser, R, Van Beeumen, J.
登録日2001-07-02
公開日2003-02-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of a Psychrophilic Metalloprotease Reveal New Insights Into Catalysis by Cold-Adapted Proteases
Proteins: Struct.,Funct., Genet., 50, 2003
5DZG
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BU of 5dzg by Molmil
Crystal Structure of the catalytic nucleophile mutant of VvEG16 in complex with a xyloglucan tetradecasaccharide
分子名称: VvEG16, endo-glucanase, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H.
登録日2015-09-25
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases.
Plant J., 89, 2017
5C33
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BU of 5c33 by Molmil
Crystal Structure of Mouse Ryanodine Receptor 2 SPRY1 Domain
分子名称: CHLORIDE ION, ISOPROPYL ALCOHOL, Ryanodine receptor 2
著者Yuchi, Z, Van Petegem, F.
登録日2015-06-16
公開日2015-08-05
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant.
Nat Commun, 6, 2015
5FDY
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BU of 5fdy by Molmil
Crystal structure of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain, C72A/C75A mutant
分子名称: GLYCEROL, Sodium channel subunit beta-2
著者Das, S, Van Petegem, F.
登録日2015-12-16
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Binary architecture of the Nav1.2-beta 2 signaling complex.
Elife, 5, 2016

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