8SEY

Cryo-EM Structure of RyR1 + Adenosine (Local Refinement of TMD)

Summary for 8SEY

Entry DOI	10.2210/pdb8sey/pdb
EMDB information	40422 40423 40424 40425 40426 40427 40428 40429 40430 40431 40432 40433 40434 40435
Descriptor	Ryanodine receptor 1, ADENOSINE, ZINC ION (3 entities in total)
Functional Keywords	calcium ion channel, skeletal muscle, nucleotide, homotetramer, transport protein
Biological source	Oryctolagus cuniculus (rabbit)
Total number of polymer chains	4
Total formula weight	2264965.10
Authors	Cholak, S.,Saville, J.W.,Zhu, X.,Berezuk, A.M.,Tuttle, K.S.,Haji-Ghassemi, O.,Van Petegem, F.,Subramaniam, S. (deposition date: 2023-04-10, release date: 2023-05-24, Last modification date: 2023-07-19)
Primary citation	Cholak, S.,Saville, J.W.,Zhu, X.,Berezuk, A.M.,Tuttle, K.S.,Haji-Ghassemi, O.,Alvarado, F.J.,Van Petegem, F.,Subramaniam, S. Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31:790-800.e4, 2023 Cited by PubMed: 37192614 DOI: 10.1016/j.str.2023.04.009 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.99 Å)

Structure validation