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PDB: 57 件
4WWU
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Structure of Mex67:Mtr2
分子名称: ZINC ION, mRNA export factor MEX67, mRNA transport regulator MTR2
著者Aibara, S, Valkov, E, Stewart, M.
登録日2014-11-12
公開日2015-02-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surface.
Nucleic Acids Res., 43, 2015
4X2O
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Sac3N peptide bound to Mex67:Mtr2
分子名称: Putative SAC3 family protein, Putative mRNA export protein, Putative uncharacterized protein
著者Aibara, S, Valkov, E, Stewart, M.
登録日2014-11-26
公開日2015-06-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2.
Structure, 23, 2015
4X2H
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Sac3N peptide bound to Mex67:Mtr2
分子名称: Putative mRNA export protein, Putative uncharacterized protein, SER-SER-VAL-PHE-GLY-ALA-PRO-ALA
著者Aibara, S, Valkov, E, Stewart, M.
登録日2014-11-26
公開日2015-06-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2.
Structure, 23, 2015
4WP6
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Structure of the Mex67 LRR domain from Chaetomium thermophilum
分子名称: mRNA export protein
著者Aibara, S, Valkov, E, Lamers, M, Stewart, M.
登録日2014-10-17
公開日2015-07-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum.
Acta Crystallogr.,Sect.F, 71, 2015
4WP5
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Chaetomium thermophilum Mex67 NTF2-like domain complexed with Mtr2
分子名称: Mtr2, mRNA export protein
著者Aibara, S, Valkov, E, Stewart, M.
登録日2014-10-17
公開日2015-07-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum.
Acta Crystallogr.,Sect.F, 71, 2015
4X2M
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Structure of Mtr2
分子名称: Mtr2
著者Aibara, S, Valkov, E, Stewart, M.
登録日2014-11-26
公開日2015-07-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum.
Acta Crystallogr.,Sect.F, 71, 2015
6FC2
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Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae
分子名称: CALCIUM ION, Eukaryotic translation initiation factor 4E, Protein EAP1
著者Gruener, S, Valkov, E.
登録日2017-12-20
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FBZ
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Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum in the cap-bound state
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-like protein,Eukaryotic translation initiation factor 4E-like protein, Eukaryotic translation initiation factor 4G
著者Gruener, S, Valkov, E.
登録日2017-12-20
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.496 Å)
主引用文献Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FC3
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Crystal structure of the eIF4E-p20 complex from Saccharomyces cerevisiae
分子名称: Cap-associated protein CAF20, Eukaryotic translation initiation factor 4E, GLYCEROL, ...
著者Gruener, S, Valkov, E.
登録日2017-12-20
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FC1
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Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae in the cap-bound state
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, GLYCEROL, ...
著者Gruener, S, Valkov, E.
登録日2017-12-20
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
3OZI
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Crystal structure of the TIR domain from the flax disease resistance protein L6
分子名称: COBALT (II) ION, L6tr
著者Ve, T, Bernoux, M, Williams, S, Valkov, E, Warren, C, Hatters, D, Ellis, J.G, Dodds, P.N, Kobe, B.
登録日2010-09-25
公開日2011-04-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation.
Cell Host Microbe, 9, 2011
6H3Z
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Crystal structure of a C-terminal MIF4G domain in NOT1
分子名称: CCR4-not transcription complex subunit 1, SODIUM ION
著者Raisch, T, Sandmeir, F, Weichenrieder, O, Valkov, E, Izaurralde, E.
登録日2018-07-19
公開日2018-11-07
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex.
J. Struct. Biol., 204, 2018
3PSN
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Crystal structure of mouse VPS29 complexed with Mn2+
分子名称: MANGANESE (II) ION, Vacuolar protein sorting-associated protein 29
著者Swarbrick, J, Shaw, D, Chhabra, S, Ghai, R, Valkov, E, Norwood, S, Collins, B.
登録日2010-12-02
公開日2010-12-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
To be Published
3PSO
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Crystal structure of mouse VPS29 complexed with Zn2+
分子名称: Vacuolar protein sorting-associated protein 29, ZINC ION
著者Swarbrick, J, Shaw, D, Chhabra, S, Ghai, R, Valkov, E, Norwood, S, Collins, B.
登録日2010-12-02
公開日2010-12-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
To be Published
6FC0
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BU of 6fc0 by Molmil
Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum
分子名称: Eukaryotic translation initiation factor 4E-like protein, Eukaryotic translation initiation factor 4G
著者Gruener, S, Valkov, E.
登録日2017-12-20
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.293 Å)
主引用文献Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
4CYI
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BU of 4cyi by Molmil
Chaetomium thermophilum Pan3
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ...
著者Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
登録日2014-04-11
公開日2014-06-11
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
4WYK
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Structure of the LRR and NTF2-like domains of NXF1 complexed with NXT1
分子名称: NTF2-related export protein 1, Nuclear RNA export factor 1
著者Aibara, S, Valkov, E, Stewart, M.
登録日2014-11-17
公開日2015-02-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The principal mRNA nuclear export factor NXF1:NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA.
Nucleic Acids Res., 43, 2015
4CYJ
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Chaetomium thermophilum Pan2:Pan3 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ...
著者Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
登録日2014-04-11
公開日2014-06-11
最終更新日2014-07-30
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
4U5L
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5V
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-{[5-(pyridin-3-yl)thiophen-2-yl]methyl}-L-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.968 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5N
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysyl-N-[(1R,2S,3R)-1-{[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino}-1,3-dihydroxybutan-2-yl]glycinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5S
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N-[(2S)-2-[(N~2~-acetyl-D-lysyl)amino]-3-(pyridin-3-ylmethoxy)propyl]-L-allothreonyl-D-phenylalaninamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U54
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-24
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U58
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzoyl]-L-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-24
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5O
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-D-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015

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