6FC1

Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae in the cap-bound state

Summary for 6FC1

Entry DOI	10.2210/pdb6fc1/pdb
Descriptor	Eukaryotic translation initiation factor 4E, Protein EAP1, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	gene expression translation translation initiation translational control, translation
Biological source	Saccharomyces cerevisiae S288C (Baker's yeast) More
Total number of polymer chains	4
Total formula weight	60455.29
Authors	Gruener, S.,Valkov, E. (deposition date: 2017-12-20, release date: 2018-06-27, Last modification date: 2024-01-17)
Primary citation	Gruner, S.,Weber, R.,Peter, D.,Chung, M.Y.,Igreja, C.,Valkov, E.,Izaurralde, E. Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast. Nucleic Acids Res., 46:6893-6908, 2018 Cited by PubMed: 30053226 DOI: 10.1093/nar/gky542 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation