6FC1
Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae in the cap-bound state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Eukaryotic translation initiation factor 4E | polymer | 193 | 21822.4 | 2 | UniProt (P07260) Pfam (PF01652) In PDB | Saccharomyces cerevisiae S288C (Baker's yeast) | eIF4E,eIF-4F 25 kDa subunit,mRNA cap-binding protein |
2 | B, D | Protein EAP1 | polymer | 64 | 7590.8 | 2 | UniProt (P36041) In PDB | Saccharomyces cerevisiae S288C (Baker's yeast) | eIF4E-associated protein 1 |
3 | A, C | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 538.2 | 2 | Chemie (MGP) | |||
4 | A, B, C, D | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
5 | water | water | 18.0 | 514 | Chemie (HOH) |
Sequence modifications
A, C: 25 - 213 (UniProt: P07260)
B, D: 91 - 150 (UniProt: P36041)
PDB | External Database | Details |
---|---|---|
Gly 21 | - | expression tag |
Pro 22 | - | expression tag |
His 23 | - | expression tag |
Met 24 | - | expression tag |
Ala 42 | Lys 42 | conflict |
Ala 122 | Lys 122 | conflict |
Ala 168 | Lys 168 | conflict |
Ala 187 | Lys 187 | conflict |
PDB | External Database | Details |
---|---|---|
Gly 87 | - | expression tag |
Pro 88 | - | expression tag |
His 89 | - | expression tag |
Met 90 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 58826.3 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1629.0 | |
All* | Total formula weight | 60455.3 |