8HHM
 
 | | Cryo-EM structure of the Cas12m2-crRNA-target DNA ternary complex intermediate state | | 分子名称: | Cas12m2, DNA (36-MER), MAGNESIUM ION, ... | | 著者 | Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O. | | 登録日 | 2022-11-16 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
|
|
8HHL
 | | Cryo-EM structure of the Cas12m2-crRNA-target DNA full R-loop complex | | 分子名称: | Cas12m2, MAGNESIUM ION, NTS (36-MER), ... | | 著者 | Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O. | | 登録日 | 2022-11-16 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | | 主引用文献 | Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
|
|
6OWN
 | |
3U9Q
 | |
4C46
 | | ANDREI-N-LVPAS fused to GCN4 adaptors | | 分子名称: | BROMIDE ION, GENERAL CONTROL PROTEIN GCN4 | | 著者 | Albrecht, R, Alva, V, Ammelburg, M, Baer, K, Basina, E, Boichenko, I, Bonhoeffer, F, Braun, V, Chaubey, M, Chauhan, N, Chellamuthu, V.R, Coles, M, Deiss, S, Ewers, C.P, Forouzan, D, Fuchs, A, Groemping, Y, Hartmann, M.D, Hernandez Alvarez, B, Jeganantham, A, Kalev, I, Koenninger, U, Koiwai, K, Kopec, K.O, Korycinski, M, Laudenbach, B, Lehmann, K, Leo, J.C, Linke, D, Marialke, J, Martin, J, Mechelke, M, Michalik, M, Noll, A, Patzer, S.I, Scharfenberg, F, Schueckel, M, Shahid, S.A, Sulz, E, Ursinus, A, Wuertenberger, S, Zhu, H. | | 登録日 | 2013-08-30 | | 公開日 | 2013-09-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Your Personalized Protein Structure: Andrei N. Lupas Fused to GCN4 Adaptors.
J.Struct.Biol., 186, 2014
|
|
6VYI
 | | Cryo-EM structure of human diacylglycerol O-acyltransferase 1 | | 分子名称: | Diacylglycerol O-acyltransferase 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | 著者 | Sui, X, Wang, K, Gluchowski, N, Liao, M, Walther, C.T, Farese, V.R. | | 登録日 | 2020-02-26 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme.
Nature, 581, 2020
|
|
6VZ1
 | | Cryo-EM structure of human diacylglycerol O-acyltransferase 1 complexed with acyl-CoA substrate | | 分子名称: | Diacylglycerol O-acyltransferase 1, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name), [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | 著者 | Sui, X, Wang, K, Gluchowski, N, Liao, M, Walther, C.T, Farese Jr, V.R. | | 登録日 | 2020-02-27 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme.
Nature, 581, 2020
|
|
6MLU
 | | Cryo-EM structure of lipid droplet formation protein Seipin/BSCL2 | | 分子名称: | Seipin | | 著者 | Sui, X, Arlt, H, Liao, M, Walther, C.T, Farese, V.R. | | 登録日 | 2018-09-28 | | 公開日 | 2018-10-17 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-electron microscopy structure of the lipid droplet-formation protein seipin.
J. Cell Biol., 217, 2018
|
|
2P7T
 | | Crystal Structure of KcsA mutant | | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB-A, FAB-B, ... | | 著者 | Cordero-Morales, J.F, Vishwanath, J, Lewis, A, Valeria, V.R, Cortes, D.M, Roux, B, Perozo, E. | | 登録日 | 2007-03-20 | | 公開日 | 2007-10-09 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal Structure of KcsA mutant
To be Published
|
|
2Y69
 | | Bovine heart cytochrome c oxidase re-refined with molecular oxygen | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, CHOLIC ACID, ... | | 著者 | Kaila, V.R.I, Oksanen, E, Goldman, A, Verkhovsky, M.I, Sundholm, D, Wikstrom, M. | | 登録日 | 2011-01-20 | | 公開日 | 2011-02-23 | | 最終更新日 | 2019-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A Combined Quantum Chemical and Crystallographic Study on the Oxidized Binuclear Center of Cytochrome C Oxidase.
Biochim.Biophys.Acta, 1807, 2011
|
|
1R2L
 | | A parallel stranded DNA duplex with an A-G mismatch base-pair | | 分子名称: | 5'-D(P*CP*CP*TP*AP*TP*GP*AP*AP*AP*TP*CP*C)-3', DNA (5'-D(P*(DNR)P*(DNR)P*DAP*DTP*DAP*DAP*DTP*DTP*DTP*DAP*(DNR)P*(DNR))-3') | | 著者 | Venkitakrishnan, R.P, Bhaumik, S.R, Chary, K.V.R, govil, G, Liu, K, Howard, F.B, Miles, T.H. | | 登録日 | 2003-09-29 | | 公開日 | 2004-10-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A parallel stranded DNA duplex with an A-G mismatch base-pair: (CCATAATTTACC:CCTATGAAATCC)
RECENT TRENDS IN BIOPHYS.RES., 2004
|
|
2I18
 | |
5ZFO
 | |
6Z0C
 | | Structure of in silico modelled artificial Maquette-3 protein | | 分子名称: | Maquette-3, POTASSIUM ION | | 著者 | Baumgart, M, Roepke, M, Muehlbauer, M.E, Asami, S, Mader, S.L, Fredriksson, K, Groll, M, Gamiz-Hernandez, A.P, Kaila, V.R.I. | | 登録日 | 2020-05-08 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Design of buried charged networks in artificial proteins
Nat Commun, 12, 2021
|
|
6Z35
 | | De-novo Maquette 2 protein with buried ion-pair | | 分子名称: | Maquette 2-1ip | | 著者 | Baumgart, M, Roepke, M, Muehlbauer, M, Asami, S, Mader, S, Fredriksson, K, Groll, M, Gamiz-Hernandez, A.P, Kaila, V.R.I. | | 登録日 | 2020-05-19 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design of buried charged networks in artificial proteins.
Nat Commun, 12, 2021
|
|
6IF9
 | |
6HXA
 | | AntI from P. luminescens catalyses terminal polyketide shortening in the biosynthesis of anthraquinones | | 分子名称: | AntI, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL | | 著者 | Zhou, Q, Braeuer, A, Grammbitter, G, Schmalhofer, M, Saura, P, Adihou, H, Kaila, V.R.I, Groll, M, Bode, H. | | 登録日 | 2018-10-16 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Molecular mechanism of polyketide shortening in anthraquinone biosynthesis ofPhotorhabdus luminescens.
Chem Sci, 10, 2019
|
|
1QE7
 | |
4BBT
 | | The PR1 Photocycle Intermediate of Photoactive Yellow Protein | | 分子名称: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | | 著者 | Schotte, F, Cho, H.S, Kaila, V.R.I, Kamikubo, H, Dashdorj, N, Henry, E.R, Graber, T.J, Henning, R, Wulff, M, Hummer, G, Kataoka, M, Anfinrud, P.A. | | 登録日 | 2012-09-27 | | 公開日 | 2012-11-14 | | 最終更新日 | 2019-01-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Watching a Signaling Protein Function in Real Time Via 100-Ps Time-Resolved Laue Crystallography.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4KQN
 | |
1DGO
 | |
4KIR
 | |
1AOJ
 | |
6EOZ
 | | Fe(II)/(alpha)ketoglutarate-dependent dioxygenase AsqJ_V72K mutant in complex with cyclopeptin (1b) | | 分子名称: | 2-OXOGLUTARIC ACID, Iron/alpha-ketoglutarate-dependent dioxygenase asqJ, NICKEL (II) ION, ... | | 著者 | Groll, M, Braeuer, A, Kaila, V.R.I. | | 登録日 | 2017-10-10 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Catalytic mechanism and molecular engineering of quinolone biosynthesis in dioxygenase AsqJ.
Nat Commun, 9, 2018
|
|
5OED
 | | Human Rab32:GDP in complex with Salmonella GtgE C45A mutant | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GtgE, MAGNESIUM ION, ... | | 著者 | Wachtel, R, Braeuning, B, Mader, S.L, Ecker, F, Kaila, V.R.I, Groll, M, Itzen, A. | | 登録日 | 2017-07-07 | | 公開日 | 2018-01-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The protease GtgE from Salmonella exclusively targets inactive Rab GTPases.
Nat Commun, 9, 2018
|
|
