8JWD
 
 | | Histidine kinase QseE sensor domain of Escherichia coli O157:H7 | | 分子名称: | 1,2-ETHANEDIOL, histidine kinase | | 著者 | Matsumoto, K, Fukuda, Y, Inoue, T. | | 登録日 | 2023-06-28 | | 公開日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Crystal structures of QseE and QseG: elements of a three-component system from Escherichia coli.
Acta Crystallogr.,Sect.F, 79, 2023
|
|
7X6G
 | |
7X6H
 | |
7X6F
 | | Outer membrane lipoprotein QseG of Escherichia coli O157:H7 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CITRATE ANION, ... | | 著者 | Matsumoto, K, Fukuda, Y, Inoue, T. | | 登録日 | 2022-03-07 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of QseE and QseG: elements of a three-component system from Escherichia coli.
Acta Crystallogr.,Sect.F, 79, 2023
|
|
3AM9
 | | Complex of bovine xanthine dehydrogenase and trihydroxy FYX-051 | | 分子名称: | 4-[5-(2,6-dioxo-1,2,3,6-tetrahydropyridin-4-yl)-1H-1,2,4-triazol-3-yl]-6-oxo-1,6-dihydropyridine-2-carbonitrile, BICARBONATE ION, CALCIUM ION, ... | | 著者 | Matsumoto, K, Okamoto, K, Ashizawa, N, Matsumura, T, Kusano, T, Nishino, T. | | 登録日 | 2010-08-18 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | FYX-051: A Novel and Potent Hybrid-Type Inhibitor of Xanthine Oxidoreductase
J.Pharmacol.Exp.Ther., 336, 2011
|
|
4W4N
 | | Crystal structure of human Fc at 1.80 A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | 著者 | Caaveiro, J.M.M, Kiyoshi, M, Tsumoto, K. | | 登録日 | 2014-08-15 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for binding of human IgG1 to its high-affinity human receptor Fc gamma RI
Nat Commun, 6, 2015
|
|
8GQ1
 | | HyHEL10 Fab complexed with hen egg lysozyme carrying arginine cluster in framework region of light chain. | | 分子名称: | Heavy Chain of HyHel10 Antibody Fragment (Fab), Light Chain of HyHel10 Antibody Fragment (Fab), Lysozyme C, ... | | 著者 | Matsuura, H, Hirata, K, Sakai, N, Nakakido, M, Tsumoto, K. | | 登録日 | 2022-08-28 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | Arginine cluster introduction on framework region in anti-lysozyme antibody improved association rate constant by changing conformational diversity of CDR loops.
Protein Sci., 32, 2023
|
|
4WD4
 | | Crystal structure of human HO1 H25R | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Caaveiro, J.M.M, Morante, K, Sigala, P, Tsumoto, K. | | 登録日 | 2014-09-06 | | 公開日 | 2015-09-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis
Biochemistry, 55, 2016
|
|
4W4O
 | | High-resolution crystal structure of Fc bound to its human receptor Fc-gamma-RI | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, GLYCEROL, ... | | 著者 | Caaveiro, J.M.M, Kiyoshi, M, Tsumoto, K. | | 登録日 | 2014-08-15 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for binding of human IgG1 to its high-affinity human receptor Fc gamma RI
Nat Commun, 6, 2015
|
|
4ZML
 | | Crystal structure of human P-cadherin (ss-dimer) | | 分子名称: | CALCIUM ION, CHLORIDE ION, Cadherin-3, ... | | 著者 | Caaveiro, J.M.M, Kudo, S, Tsumoto, K. | | 登録日 | 2015-05-04 | | 公開日 | 2016-09-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Adhesive Dimerization of Human P-Cadherin Catalyzed by a Chaperone-like Mechanism
Structure, 24, 2016
|
|
4ZMV
 | | Crystal structure of human P-cadherin (ss-X-dimer pocket I) | | 分子名称: | CALCIUM ION, Cadherin-3, GLYCEROL, ... | | 著者 | Caaveiro, J.M.M, Kudo, S, Tsumoto, K. | | 登録日 | 2015-05-04 | | 公開日 | 2016-09-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Adhesive Dimerization of Human P-Cadherin Catalyzed by a Chaperone-like Mechanism
Structure, 24, 2016
|
|
1C08
 | | CRYSTAL STRUCTURE OF HYHEL-10 FV-HEN LYSOZYME COMPLEX | | 分子名称: | ANTI-HEN EGG WHITE LYSOZYME ANTIBODY (HYHEL-10), LYSOZYME | | 著者 | Shiroishi, M, Kondo, H, Matsushima, M, Tsumoto, K, Kumagai, I. | | 登録日 | 1999-07-15 | | 公開日 | 2000-07-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of anti-Hen egg white lysozyme antibody (HyHEL-10) Fv-antigen complex. Local structural changes in the protein antigen and water-mediated interactions of Fv-antigen and light chain-heavy chain interfaces.
J.Biol.Chem., 274, 1999
|
|
5JYL
 | | Human P-cadherin MEC1 with scFv TSP7 bound | | 分子名称: | CHLORIDE ION, Cadherin-3, GLYCEROL, ... | | 著者 | Caaveiro, J.M.M, Kudo, S, Tsumoto, K. | | 登録日 | 2016-05-14 | | 公開日 | 2016-12-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin
Sci Rep, 7, 2017
|
|
1FKV
 | | RECOMBINANT GOAT ALPHA-LACTALBUMIN T29I | | 分子名称: | ALPHA-LACTALBUMIN, CALCIUM ION | | 著者 | Horii, K, Matsushima, M, Tsumoto, K, Kumagai, I. | | 登録日 | 2000-08-10 | | 公開日 | 2001-02-14 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Contribution of Thr29 to the thermodynamic stability of goat alpha-lactalbumin as determined by experimental and theoretical approaches.
Proteins, 45, 2001
|
|
1FKQ
 | | RECOMBINANT GOAT ALPHA-LACTALBUMIN T29V | | 分子名称: | ALPHA-LACTALBUMIN, CALCIUM ION | | 著者 | Horii, K, Matsushima, M, Tsumoto, K, Kumagai, I. | | 登録日 | 2000-08-10 | | 公開日 | 2001-02-14 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of Thr29 to the thermodynamic stability of goat alpha-lactalbumin as determined by experimental and theoretical approaches.
Proteins, 45, 2001
|
|
7CME
 | | Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor) | | 分子名称: | 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ... | | 著者 | Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. | | 登録日 | 2020-07-27 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
Commun Biol, 4, 2021
|
|
7CMF
 | | Crystal structure of human P-cadherin REC12 (monomer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor) | | 分子名称: | 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3 | | 著者 | Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. | | 登録日 | 2020-07-27 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
Commun Biol, 4, 2021
|
|
4WDC
 | |
8JOW
 | |
3GP7
 | |
4G5H
 | | Crystal structure of capsular polysaccharide synthesizing enzyme CapE from Staphylococcus aureus in complex with by-product | | 分子名称: | Capsular polysaccharide synthesis enzyme Cap8E, FORMIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Miyafusa, T, Caaveiro, J.M.M, Tanaka, Y, Tsumoto, K. | | 登録日 | 2012-07-18 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Dynamic elements govern the catalytic activity of CapE, a capsular polysaccharide-synthesizing enzyme from Staphylococcus aureus.
Febs Lett., 587, 2013
|
|
5JYM
 | |
8JUU
 | | rat megalin | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Goto, S, Tsutsumi, A, Lee, Y, Hosojima, M, Kabasawa, H, Komochi, K, Yun-san, L, Nagatoshi, S, Tsumoto, K, Nishizawa, T, Kikkawa, M, Saito, A. | | 登録日 | 2023-06-27 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
8JX9
 | | rat megalin bodyA | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Goto, S, Tsutsumi, A, Lee, Y, Hosojima, M, Kabasawa, H, Komochi, K, Yun-san, L, Nagatoshi, S, Tsumoto, K, Nishizawa, T, Kikkawa, M, Saito, A. | | 登録日 | 2023-06-30 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
8JX8
 | | rat megalin head | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Goto, S, Tsutsumi, A, Lee, Y, Hosojima, M, Kabasawa, H, Komochi, K, Yun-san, L, Nagatoshi, S, Tsumoto, K, Nishizawa, T, Kikkawa, M, Saito, A. | | 登録日 | 2023-06-30 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
