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PDB: 18 results

7ABH
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BU of 7abh by Molmil
Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)
Descriptor: Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ...
Authors:Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
Deposit date:2020-09-07
Release date:2020-12-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7ABF
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BU of 7abf by Molmil
Human pre-Bact-1 spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
Deposit date:2020-09-07
Release date:2020-12-09
Last modified:2020-12-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7AAV
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BU of 7aav by Molmil
Human pre-Bact-2 spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ...
Authors:Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
Deposit date:2020-09-04
Release date:2020-12-09
Last modified:2020-12-30
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7ABG
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BU of 7abg by Molmil
Human pre-Bact-1 spliceosome
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ...
Authors:Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
Deposit date:2020-09-07
Release date:2020-12-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7ABI
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BU of 7abi by Molmil
Human pre-Bact-2 spliceosome
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ...
Authors:Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
Deposit date:2020-09-07
Release date:2021-02-10
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
1JGT
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BU of 1jgt by Molmil
CRYSTAL STRUCTURE OF BETA-LACTAM SYNTHETASE
Descriptor: BETA-LACTAM SYNTHETASE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, GLYCEROL, ...
Authors:Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C.
Deposit date:2001-06-26
Release date:2001-12-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of beta-lactam synthetase reveals how to synthesize antibiotics instead of asparagine.
Nat.Struct.Biol., 8, 2001
5KBZ
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BU of 5kbz by Molmil
Structure of the PksA Product Template domain in complex with a phosphopantetheine mimetic
Descriptor: (14R)-14-hydroxy-15,15-dimethyl-1-[5-({[(5-methyl-1,2-oxazol-3-yl)methyl]sulfanyl}methyl)-1,2-oxazol-3-yl]-4,9,13-trioxo-2-thia-5,8,12-triazahexadecan-16-yl dihydrogen phosphate, Noranthrone synthase
Authors:Tsai, S.C, Burkart, M.D, Townsend, C.A, Barajas, J.F, Shakya, G, Topper, C.L, Moreno, G, Jackson, D.R, Rivera, H, La Clair, J.J, Vagstad, A.
Deposit date:2016-06-03
Release date:2017-05-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6FIJ
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BU of 6fij by Molmil
Structure of the loading/condensing region (SAT-KS-MAT) of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1
Descriptor: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, ...
Authors:Herbst, D.A, Jakob, R.P, Townsend, C.A, Maier, T.
Deposit date:2018-01-18
Release date:2018-03-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:The structural organization of substrate loading in iterative polyketide synthases.
Nat. Chem. Biol., 14, 2018
6FIK
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BU of 6fik by Molmil
ACP2 crosslinked to the KS of the loading/condensing region of the CTB1 PKS
Descriptor: Polyketide synthase
Authors:Herbst, D.A, Huitt-Roehl, C.R, Jakob, R.P, Townsend, C.A, Maier, T.
Deposit date:2018-01-18
Release date:2018-03-21
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:The structural organization of substrate loading in iterative polyketide synthases.
Nat. Chem. Biol., 14, 2018
1Q19
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BU of 1q19 by Molmil
Carbapenam Synthetase
Descriptor: (2S,5S)-5-CARBOXYMETHYLPROLINE, CarA, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Miller, M.T, Gerratana, B, Stapon, A, Townsend, C.A, Rosenzweig, A.C.
Deposit date:2003-07-18
Release date:2003-11-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Carbapenam Synthetase (CarA)
J.Biol.Chem., 278, 2003
5MPT
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BU of 5mpt by Molmil
Structure of the citrinin polyketide synthase CMeT domain
Descriptor: 1,2-ETHANEDIOL, Citrinin polyketide synthase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Herbst, D.A, Storm, P.A, Townsend, C.A, Maier, T.
Deposit date:2016-12-19
Release date:2017-02-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.648 Å)
Cite:Functional and Structural Analysis of Programmed C-Methylation in the Biosynthesis of the Fungal Polyketide Citrinin.
Cell Chem Biol, 24, 2017
1Q15
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BU of 1q15 by Molmil
Carbapenam Synthetase
Descriptor: CarA
Authors:Miller, M.T, Gerratana, B, Stapon, A, Townsend, C.A, Rosenzweig, A.C.
Deposit date:2003-07-18
Release date:2003-11-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Carbapenam Synthetase (CarA)
J.Biol.Chem., 278, 2003
4IHD
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BU of 4ihd by Molmil
Crystal Structure of Uncleaved ThnT T282C, derivatized at the active site with EtHg
Descriptor: ETHYL MERCURY ION, ThnT protein
Authors:Buller, A.R, Schildbach, J.F, Townsend, C.A.
Deposit date:2012-12-18
Release date:2014-08-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Exploring the Role of Conformational Heterogeneity in cis-Autoproteolytic Activation of ThnT.
Biochemistry, 53, 2014
4IHE
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BU of 4ihe by Molmil
Crystal Structure of Uncleaved ThnT T282A
Descriptor: ThnT protein
Authors:Buller, A.R, Schildbach, J.F, Townsend, C.A.
Deposit date:2012-12-18
Release date:2014-08-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Exploring the Role of Conformational Heterogeneity in cis-Autoproteolytic Activation of ThnT.
Biochemistry, 53, 2014
1MBZ
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BU of 1mbz by Molmil
BETA-LACTAM SYNTHETASE WITH TRAPPED INTERMEDIATE
Descriptor: ARGININE-N-METHYLCARBONYL PHOSPHORIC ACID 5'-ADENOSINE ESTER, BETA-LACTAM SYNTHETASE, GLYCEROL, ...
Authors:Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C.
Deposit date:2002-08-04
Release date:2002-10-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots
Proc.Natl.Acad.Sci.USA, 99, 2002
1M1Z
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BU of 1m1z by Molmil
BETA-LACTAM SYNTHETASE APO ENZYME
Descriptor: BETA-LACTAM SYNTHETASE
Authors:Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C.
Deposit date:2002-06-20
Release date:2002-10-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots
Proc.Natl.Acad.Sci.USA, 99, 2002
1MC1
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BU of 1mc1 by Molmil
BETA-LACTAM SYNTHETASE WITH PRODUCT (DGPC), AMP AND PPI
Descriptor: ADENOSINE MONOPHOSPHATE, BETA-LACTAM SYNTHETASE, DEOXYGUANIDINOPROCLAVAMINIC ACID, ...
Authors:Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C.
Deposit date:2002-08-04
Release date:2002-10-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots
Proc.Natl.Acad.Sci.USA, 99, 2002
1MB9
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BU of 1mb9 by Molmil
BETA-LACTAM SYNTHETASE COMPLEXED WITH ATP
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, BETA-LACTAM SYNTHETASE, ...
Authors:Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C.
Deposit date:2002-08-02
Release date:2002-10-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots
Proc.Natl.Acad.Sci.USA, 99, 2002

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