6FIK

ACP2 crosslinked to the KS of the loading/condensing region of the CTB1 PKS

Summary for 6FIK

• Entry DOI: 10.2210/pdb6fik/pdb
• Related: 6FIJ
• EMDB information: 4266
• Descriptor: Polyketide synthase (2 entities in total)
• Functional Keywords: nr-pks, pks, ipks, iterative pks, non-reducing, sat, starter acyl, condensing, loading, polyketide, fungal, crosslink, acp, acyl carrier, transferase, biosynthetic protein
• Biological source: Cercospora nicotianae (Barn spot disease fungus); More
• Total number of polymer chains: 3
• Total formula weight: 290402.84

Authors

Herbst, D.A.,Huitt-Roehl, C.R.,Jakob, R.P.,Townsend, C.A.,Maier, T. (deposition date: 2018-01-18, release date: 2018-03-21, Last modification date: 2019-12-11)

• Primary citation: Herbst, D.A.,Huitt-Roehl, C.R.,Jakob, R.P.,Kravetz, J.M.,Storm, P.A.,Alley, J.R.,Townsend, C.A.,Maier, T.; The structural organization of substrate loading in iterative polyketide synthases.; Nat. Chem. Biol., 14:474-479, 2018; PubMed: 29610486; DOI: 10.1038/s41589-018-0026-3

Experimental method

ELECTRON MICROSCOPY (7.1 Å)