4IHD

Crystal Structure of Uncleaved ThnT T282C, derivatized at the active site with EtHg

Summary for 4IHD

Entry DOI	10.2210/pdb4ihd/pdb
Related	3S3U 3TM1 3TM2 4IHE
Descriptor	ThnT protein, ETHYL MERCURY ION (3 entities in total)
Functional Keywords	dom-fold, clan pe, family p1, autoproteolysis, pantetheine hydrolase, thienamycin biosynthesis, ethylmercury derivatization of c282, hydrolase
Biological source	Streptomyces cattleya
Total number of polymer chains	2
Total formula weight	83207.54
Authors	Buller, A.R.,Schildbach, J.F.,Townsend, C.A. (deposition date: 2012-12-18, release date: 2014-08-13, Last modification date: 2023-09-20)
Primary citation	Buller, A.R.,Freeman, M.F.,Schildbach, J.F.,Townsend, C.A. Exploring the Role of Conformational Heterogeneity in cis-Autoproteolytic Activation of ThnT. Biochemistry, 53:4273-4281, 2014 Cited by PubMed: 24933323 DOI: 10.1021/bi500385d PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation