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PDB: 97 件

7QZ6
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Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5-fluoroTrp
分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family
著者Thunnissen, A.M.W.H.
登録日2022-01-30
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach.
J.Am.Chem.Soc., 144, 2022
8QDH
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BU of 8qdh by Molmil
Engineered LmrR carrying a cyclic boronate ester formed between Tris and p-boronophenylalanine at position 89
分子名称: GLYCEROL, Transcriptional regulator, PadR-like family
著者Thunnissen, A.M.W.H, Rozeboom, H.J, Longwitz, L, Leveson-Gower, R.B, Roelfes, G.
登録日2023-08-29
公開日2024-05-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Boron catalysis in a designer enzyme.
Nature, 629, 2024
8QDF
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BU of 8qdf by Molmil
Engineered LmrR with Met-89 replaced by para-boronophenylalanine
分子名称: Transcriptional regulator, PadR-like family
著者Thunnissen, A.M.W.H, Rozeboom, H.J, Longwitz, L, Leveson-Gower, R.B, Roelfes, G.
登録日2023-08-29
公開日2024-05-01
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Boron catalysis in a designer enzyme.
Nature, 629, 2024
8RDH
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BU of 8rdh by Molmil
Crystal structure of UDP-galactose 4-epimerase from Pyrococcus horikoshii with bound NAD and GDP-L-fucose
分子名称: GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SDR family NAD(P)-dependent oxidoreductase
著者Thunnissen, A.M.W.H, Alvarez Quispe, C, Desmet, T.
登録日2023-12-08
公開日2024-12-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural, computational and biochemical analysis reveal new insights in the specificity of a promiscuous GDP-Gal4E
To Be Published
8RDI
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BU of 8rdi by Molmil
Crystal structure of UDP-galactose 4-epimerase from Pyrococcus horikoshii containing Y145F mutation and with bound NAD and GDP-L-fucose
分子名称: GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SDR family NAD(P)-dependent oxidoreductase
著者Thunnissen, A.M.W.H, Alvarez Quispe, C, Desmet, T.
登録日2023-12-08
公開日2024-12-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural, computational and biochemical analysis reveal new insights in the specificity of a promiscuous GDP-Gal4E
To Be Published
8RDG
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BU of 8rdg by Molmil
Crystal structure of UDP-galactose 4-epimerase from Pyrococcus horikoshii with bound NAD
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SDR family NAD(P)-dependent oxidoreductase
著者Thunnissen, A.M.W.H, Alvarez Quispe, C, Desmet, T.
登録日2023-12-08
公開日2024-12-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural, computational and biochemical analysis reveal new insights in the specificity of a promiscuous GDP-Gal4E
To Be Published
1IIG
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BU of 1iig by Molmil
STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHONOPROPIONATE
分子名称: 3-PHOSPHONOPROPANOIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Noble, M.E, Wierenga, R.K, Lambeir, A.M, Opperdoes, F.R, Thunnissen, A.M, Kalk, K.H, Groendijk, H, Hol, W.G.J.
登録日2001-04-23
公開日2001-05-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Proteins, 10, 1991
1IIH
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STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHOGLYCERATE
分子名称: 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Noble, M.E, Wierenga, R.K, Lambeir, A.M, Opperdoes, F.R, Thunnissen, A.M, Kalk, K.H, Groendijk, H, Hol, W.G.J.
登録日2001-04-23
公開日2001-05-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Proteins, 10, 1991
1OXT
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BU of 1oxt by Molmil
Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
分子名称: ABC transporter, ATP binding protein
著者Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M.
登録日2003-04-03
公開日2003-06-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations
J.Mol.Biol., 330, 2003
1OXS
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BU of 1oxs by Molmil
Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
分子名称: ABC transporter, ATP binding protein, IODIDE ION
著者Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M.
登録日2003-04-03
公開日2003-06-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations
J.Mol.Biol., 330, 2003
1OXV
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BU of 1oxv by Molmil
Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
分子名称: ABC transporter, ATP binding protein, IODIDE ION, ...
著者Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M.
登録日2003-04-03
公開日2003-06-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations
J.Mol.Biol., 330, 2003
1OXU
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BU of 1oxu by Molmil
Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
分子名称: ABC transporter, ATP binding protein, ADENOSINE-5'-DIPHOSPHATE, ...
著者Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M.
登録日2003-04-03
公開日2003-06-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations
J.Mol.Biol., 330, 2003
6RX8
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BU of 6rx8 by Molmil
EDDS lyase variant D290M/Y320M with bound fumarate
分子名称: Argininosuccinate lyase, FUMARIC ACID, SODIUM ION
著者Grandi, E, Poelarends, G.J, Thunnissen, A.M.W.H.
登録日2019-06-07
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Engineered C-N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners.
Angew.Chem.Int.Ed.Engl., 59, 2020
6F88
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BU of 6f88 by Molmil
Crystal structure of cytochrome P450 CYP260A1 (S276N) bound with progesterone
分子名称: Cytochrome P450 CYP260A1, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE
著者Jozwik, I.K, Thunnissen, A.M.W.H.
登録日2017-12-12
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone.
ACS Chem. Biol., 13, 2018
6I8N
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BU of 6i8n by Molmil
Crystal structure of LmrR with V15 replaced by unnatural amino acid 4-amino-L-phenylalanine
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Transcriptional regulator, PadR-like family
著者Reddem, R, Thunnissen, A.M.W.H.
登録日2018-11-20
公開日2019-01-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid.
Angew. Chem. Int. Ed. Engl., 58, 2019
8RJ1
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BU of 8rj1 by Molmil
Crystal structure of mutant aspartase from Caenibacillus caldisaponilyticus in the closed loop conformation
分子名称: Aspartate ammonia lyase
著者Capra, N, Thunnissen, A.M.W.H, Janssen, D.B.
登録日2023-12-19
公開日2025-01-15
最終更新日2025-02-05
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Bioinformatics and Computationally Supported Redesign of Aspartase for beta-Alanine Synthesis by Acrylic Acid Hydroamination.
Acs Catalysis, 15, 2025
8RJ0
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BU of 8rj0 by Molmil
Crystal structure of mutant aspartase from Bacillus sp. YM55-1 in the closed loop conformation
分子名称: Aspartate ammonia-lyase, SODIUM ION, TRIETHYLENE GLYCOL
著者Capra, N, Thunnissen, A.M.W.H, Janssen, D.B.
登録日2023-12-19
公開日2025-01-15
最終更新日2025-02-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Bioinformatics and Computationally Supported Redesign of Aspartase for beta-Alanine Synthesis by Acrylic Acid Hydroamination.
Acs Catalysis, 15, 2025
7QQJ
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BU of 7qqj by Molmil
Sucrose phosphorylase from Jeotgalibaca ciconiae
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Sucrose phosphorylase
著者Ubiparip, Z, Capra, N, Rozeboom, H.J, Desmet, T, Thunnissen, A.M.W.H.
登録日2022-01-08
公開日2023-01-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Sucrose phosphorylase from Jeotgalibaca ciconiae
To Be Published
7QQI
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BU of 7qqi by Molmil
Sucrose phosphorylase from Faecalibaculum rodentium
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aamy domain-containing protein
著者Ubiparip, Z, Capra, N, Rozeboom, H.J, Desmet, T, Thunnissen, A.M.W.H.
登録日2022-01-08
公開日2023-01-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Sucrose phosphorylase from Faecalibaculum rodentium
To Be Published
7PUO
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BU of 7puo by Molmil
Structure of a fused 4-OT variant engineered for asymmetric Michael addition reactions
分子名称: 2-hydroxymuconate tautomerase,Chains: A,B,C,D,E,F,2-hydroxymuconate tautomerase, CHLORIDE ION, GLYCEROL
著者Rozeboom, H.J, Thunnissen, A.M.W.H, Poelarends, G.J.
登録日2021-09-30
公開日2022-01-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Gene Fusion and Directed Evolution to Break Structural Symmetry and Boost Catalysis by an Oligomeric C-C Bond-Forming Enzyme.
Angew.Chem.Int.Ed.Engl., 61, 2022
6R1L
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BU of 6r1l by Molmil
Crystal structure of LmrR with bound copper phenanthroline
分子名称: 1,10-PHENANTHROLINE, COPPER (II) ION, Transcriptional regulator, ...
著者Reddem, R, Thunnissen, A.M.W.H.
登録日2019-03-14
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.095 Å)
主引用文献Cofactor Binding Dynamics Influence the Catalytic Activity and Selectivity of an Artificial Metalloenzyme.
Acs Catalysis, 10, 2020
7B4I
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BU of 7b4i by Molmil
Thermostable omega transaminase PjTA-R6 variant W58G engineered for asymmetric synthesis of enantiopure bulky amines
分子名称: Aspartate aminotransferase family protein, PYRIDOXAL-5'-PHOSPHATE, SUCCINIC ACID
著者Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B.
登録日2020-12-02
公開日2021-09-01
最終更新日2021-09-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Computational Redesign of an omega-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines.
Acs Catalysis, 11, 2021
7B4J
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BU of 7b4j by Molmil
Thermostable omega transaminase PjTA-R6 variant W58M/F86L/R417L engineered for asymmetric synthesis of enantiopure bulky amines
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase family protein, SUCCINIC ACID
著者Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B.
登録日2020-12-02
公開日2021-09-01
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Computational Redesign of an omega-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines.
Acs Catalysis, 11, 2021
5MDX
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BU of 5mdx by Molmil
Cryo-EM structure of the PSII supercomplex from Arabidopsis thaliana
分子名称: CHLOROPHYLL A, CHLOROPHYLL B, Chlorophyll a-b binding protein 1, ...
著者van Bezouwen, L.S, Caffarri, S, Kale, R.S, Kouril, R, Thunnissen, A.M.W.H, Oostergetel, G.T, Boekema, E.J.
登録日2016-11-13
公開日2017-06-21
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Subunit and chlorophyll organization of the plant photosystem II supercomplex.
Nat Plants, 3, 2017
5OFQ
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BU of 5ofq by Molmil
Crystal structure of substrate-free CYP109A2 from Bacillus megaterium
分子名称: Cytochrome P450, PENTAETHYLENE GLYCOL, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Jozwik, I.K, Thunnissen, A.M.W.H.
登録日2017-07-11
公開日2017-09-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Biochemical and structural characterization of CYP109A2, a vitamin D3 25-hydroxylase from Bacillus megaterium.
FEBS J., 284, 2017

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件を2025-04-23に公開中

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