6I8N

Crystal structure of LmrR with V15 replaced by unnatural amino acid 4-amino-L-phenylalanine

Summary for 6I8N

Entry DOI	10.2210/pdb6i8n/pdb
Descriptor	Transcriptional regulator, PadR-like family, 3[N-MORPHOLINO]PROPANE SULFONIC ACID (3 entities in total)
Functional Keywords	padr family, transcriptional regulator, engineered variant, artificial enzyme, unnatural amino acid, dna binding protein
Biological source	Lactococcus lactis subsp. cremoris (strain MG1363)
Total number of polymer chains	2
Total formula weight	29864.95
Authors	Reddem, R.,Thunnissen, A.M.W.H. (deposition date: 2018-11-20, release date: 2019-01-02, Last modification date: 2024-01-24)
Primary citation	Mayer, C.,Dulson, C.,Reddem, E.,Thunnissen, A.W.H.,Roelfes, G. Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid. Angew. Chem. Int. Ed. Engl., 58:2083-2087, 2019 Cited by PubMed: 30575260 DOI: 10.1002/anie.201813499 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.79 Å)

Structure validation