7B4I

Thermostable omega transaminase PjTA-R6 variant W58G engineered for asymmetric synthesis of enantiopure bulky amines

This is a non-PDB format compatible entry.

Summary for 7B4I

• Entry DOI: 10.2210/pdb7b4i/pdb
• Descriptor: Aspartate aminotransferase family protein, PYRIDOXAL-5'-PHOSPHATE, SUCCINIC ACID, ... (4 entities in total)
• Functional Keywords: aminotransferase, transaminase, amine synthesis, enantioselective, thermostable, engineered, transferase
• Biological source: Pseudomonas sp.
• Total number of polymer chains: 2
• Total formula weight: 101869.74

Authors

Capra, N.,Rozeboom, H.J.,Thunnissen, A.M.W.H.,Janssen, D.B. (deposition date: 2020-12-02, release date: 2021-09-01, Last modification date: 2021-09-22)

• Primary citation: Meng, Q.,Ramirez-Palacios, C.,Capra, N.,Hooghwinkel, M.E.,Thallmair, S.,Rozeboom, H.J.,Thunnissen, A.W.H.,Wijma, H.J.,Marrink, S.J.,Janssen, D.B.; Computational Redesign of an omega-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines.; Acs Catalysis, 11:10733-10747, 2021; PubMed: 34504735; DOI: 10.1021/acscatal.1c02053

Experimental method

X-RAY DIFFRACTION (1.7 Å)