6F88
Crystal structure of cytochrome P450 CYP260A1 (S276N) bound with progesterone
Summary for 6F88
Entry DOI | 10.2210/pdb6f88/pdb |
Descriptor | Cytochrome P450 CYP260A1, PROTOPORPHYRIN IX CONTAINING FE, PROGESTERONE, ... (4 entities in total) |
Functional Keywords | bacterial proteins, sorangium cellulosum, cytochrome p-450 enzyme system, cytochrome p450, hydroxylation, heme, oxidation-reduction, progesterone, histidine, biocatalysis, oxidoreductase |
Biological source | Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56)) |
Total number of polymer chains | 2 |
Total formula weight | 90911.74 |
Authors | Jozwik, I.K.,Thunnissen, A.M.W.H. (deposition date: 2017-12-12, release date: 2018-03-14, Last modification date: 2024-01-17) |
Primary citation | Khatri, Y.,Jozwik, I.K.,Ringle, M.,Ionescu, I.A.,Litzenburger, M.,Hutter, M.C.,Thunnissen, A.W.H.,Bernhardt, R. Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone. ACS Chem. Biol., 13:1021-1028, 2018 Cited by PubMed: 29509407DOI: 10.1021/acschembio.8b00026 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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