8RDI

Crystal structure of UDP-galactose 4-epimerase from Pyrococcus horikoshii containing Y145F mutation and with bound NAD and GDP-L-fucose

Summary for 8RDI

• Entry DOI: 10.2210/pdb8rdi/pdb
• Descriptor: SDR family NAD(P)-dependent oxidoreductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE (3 entities in total)
• Functional Keywords: udp-galactose 4-epimerase, gale, rossmann fold, gdp-l-fucose, isomerase
• Biological source: Pyrococcus horikoshii
• Total number of polymer chains: 4
• Total formula weight: 151794.24

Authors

Thunnissen, A.M.W.H.,Alvarez Quispe, C.,Desmet, T. (deposition date: 2023-12-08, release date: 2024-12-18)

• Primary citation: Alvarez Quispe, C.,Savino, S.,Biarnes, X.,Planas, A.,Thunnissen, A.M.W.H.,Beerens, K.,Desmet, T.; Structural, computational and biochemical analysis reveal new insights in the specificity of a promiscuous GDP-Gal4E; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.1 Å)