6RX8

EDDS lyase variant D290M/Y320M with bound fumarate

Summary for 6RX8

Entry DOI	10.2210/pdb6rx8/pdb
Descriptor	Argininosuccinate lyase, FUMARIC ACID, SODIUM ION, ... (4 entities in total)
Functional Keywords	edds lyase, c-n lyase, aspartase/fumarase, protein engineering, lyase
Biological source	Chelativorans sp. (strain BNC1)
Total number of polymer chains	1
Total formula weight	56020.50
Authors	Grandi, E.,Poelarends, G.J.,Thunnissen, A.M.W.H. (deposition date: 2019-06-07, release date: 2019-10-30, Last modification date: 2024-01-24)
Primary citation	Zhang, J.,Grandi, E.,Fu, H.,Saravanan, T.,Bothof, L.,Tepper, P.G.,Thunnissen, A.W.H.,Poelarends, G.J. Engineered C-N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners. Angew.Chem.Int.Ed.Engl., 59:429-435, 2020 Cited by PubMed: 31625664 DOI: 10.1002/anie.201910704 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.92 Å)

Structure validation