6RX8

EDDS lyase variant D290M/Y320M with bound fumarate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004056	molecular_function	argininosuccinate lyase activity
A	0005829	cellular_component	cytosol
A	0006526	biological_process	L-arginine biosynthetic process
A	0016829	molecular_function	lyase activity
A	0042450	biological_process	arginine biosynthetic process via ornithine

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue FUM A 601

Chain	Residue
A	SER111
A	LYS286
A	ASN288
A	ARG112
A	ASN113
A	THR158
A	GLN159
A	SER280
A	SER281
A	ILE282
A	MET283

---

site_id	AC2
Number of Residues	11
Details	binding site for residue FUM A 602

Chain	Residue
A	TYR26
A	ARG112
A	MET290
A	ARG294
A	HOH702
A	HOH708
A	HOH713
A	HOH736
A	HOH831
A	HOH874
A	HOH877

---

site_id	AC3
Number of Residues	6
Details	binding site for residue NA A 603

Chain	Residue
A	GLU188
A	GLU188
A	ARG192
A	ARG192
A	HOH710
A	HOH710

---

site_id	AC4
Number of Residues	4
Details	binding site for residue NA A 604

Chain	Residue
A	LYS181
A	ARG185
A	HIS237
A	HOH824

---