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PDB: 97 results

7QZ6
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BU of 7qz6 by Molmil
Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5-fluoroTrp
Descriptor: DAUNOMYCIN, Transcriptional regulator, PadR-like family
Authors:Thunnissen, A.M.W.H.
Deposit date:2022-01-30
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach.
J.Am.Chem.Soc., 144, 2022
8QDH
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BU of 8qdh by Molmil
Engineered LmrR carrying a cyclic boronate ester formed between Tris and p-boronophenylalanine at position 89
Descriptor: GLYCEROL, Transcriptional regulator, PadR-like family
Authors:Thunnissen, A.M.W.H, Rozeboom, H.J, Longwitz, L, Leveson-Gower, R.B, Roelfes, G.
Deposit date:2023-08-29
Release date:2024-05-01
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Boron catalysis in a designer enzyme.
Nature, 629, 2024
8QDF
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BU of 8qdf by Molmil
Engineered LmrR with Met-89 replaced by para-boronophenylalanine
Descriptor: Transcriptional regulator, PadR-like family
Authors:Thunnissen, A.M.W.H, Rozeboom, H.J, Longwitz, L, Leveson-Gower, R.B, Roelfes, G.
Deposit date:2023-08-29
Release date:2024-05-01
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Boron catalysis in a designer enzyme.
Nature, 629, 2024
8RDH
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BU of 8rdh by Molmil
Crystal structure of UDP-galactose 4-epimerase from Pyrococcus horikoshii with bound NAD and GDP-L-fucose
Descriptor: GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SDR family NAD(P)-dependent oxidoreductase
Authors:Thunnissen, A.M.W.H, Alvarez Quispe, C, Desmet, T.
Deposit date:2023-12-08
Release date:2024-12-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural, computational and biochemical analysis reveal new insights in the specificity of a promiscuous GDP-Gal4E
To Be Published
8RDI
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BU of 8rdi by Molmil
Crystal structure of UDP-galactose 4-epimerase from Pyrococcus horikoshii containing Y145F mutation and with bound NAD and GDP-L-fucose
Descriptor: GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SDR family NAD(P)-dependent oxidoreductase
Authors:Thunnissen, A.M.W.H, Alvarez Quispe, C, Desmet, T.
Deposit date:2023-12-08
Release date:2024-12-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural, computational and biochemical analysis reveal new insights in the specificity of a promiscuous GDP-Gal4E
To Be Published
8RDG
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BU of 8rdg by Molmil
Crystal structure of UDP-galactose 4-epimerase from Pyrococcus horikoshii with bound NAD
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SDR family NAD(P)-dependent oxidoreductase
Authors:Thunnissen, A.M.W.H, Alvarez Quispe, C, Desmet, T.
Deposit date:2023-12-08
Release date:2024-12-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural, computational and biochemical analysis reveal new insights in the specificity of a promiscuous GDP-Gal4E
To Be Published
6RX8
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BU of 6rx8 by Molmil
EDDS lyase variant D290M/Y320M with bound fumarate
Descriptor: Argininosuccinate lyase, FUMARIC ACID, SODIUM ION
Authors:Grandi, E, Poelarends, G.J, Thunnissen, A.M.W.H.
Deposit date:2019-06-07
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Engineered C-N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners.
Angew.Chem.Int.Ed.Engl., 59, 2020
6F88
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BU of 6f88 by Molmil
Crystal structure of cytochrome P450 CYP260A1 (S276N) bound with progesterone
Descriptor: Cytochrome P450 CYP260A1, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2017-12-12
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone.
ACS Chem. Biol., 13, 2018
6I8N
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BU of 6i8n by Molmil
Crystal structure of LmrR with V15 replaced by unnatural amino acid 4-amino-L-phenylalanine
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Transcriptional regulator, PadR-like family
Authors:Reddem, R, Thunnissen, A.M.W.H.
Deposit date:2018-11-20
Release date:2019-01-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid.
Angew. Chem. Int. Ed. Engl., 58, 2019
8RJ1
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BU of 8rj1 by Molmil
Crystal structure of mutant aspartase from Caenibacillus caldisaponilyticus in the closed loop conformation
Descriptor: Aspartate ammonia lyase
Authors:Capra, N, Thunnissen, A.M.W.H, Janssen, D.B.
Deposit date:2023-12-19
Release date:2025-01-15
Last modified:2025-02-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Bioinformatics and Computationally Supported Redesign of Aspartase for beta-Alanine Synthesis by Acrylic Acid Hydroamination.
Acs Catalysis, 15, 2025
8RJ0
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BU of 8rj0 by Molmil
Crystal structure of mutant aspartase from Bacillus sp. YM55-1 in the closed loop conformation
Descriptor: Aspartate ammonia-lyase, SODIUM ION, TRIETHYLENE GLYCOL
Authors:Capra, N, Thunnissen, A.M.W.H, Janssen, D.B.
Deposit date:2023-12-19
Release date:2025-01-15
Last modified:2025-02-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Bioinformatics and Computationally Supported Redesign of Aspartase for beta-Alanine Synthesis by Acrylic Acid Hydroamination.
Acs Catalysis, 15, 2025
7QQJ
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BU of 7qqj by Molmil
Sucrose phosphorylase from Jeotgalibaca ciconiae
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Sucrose phosphorylase
Authors:Ubiparip, Z, Capra, N, Rozeboom, H.J, Desmet, T, Thunnissen, A.M.W.H.
Deposit date:2022-01-08
Release date:2023-01-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Sucrose phosphorylase from Jeotgalibaca ciconiae
To Be Published
7QQI
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BU of 7qqi by Molmil
Sucrose phosphorylase from Faecalibaculum rodentium
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aamy domain-containing protein
Authors:Ubiparip, Z, Capra, N, Rozeboom, H.J, Desmet, T, Thunnissen, A.M.W.H.
Deposit date:2022-01-08
Release date:2023-01-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Sucrose phosphorylase from Faecalibaculum rodentium
To Be Published
7PUO
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BU of 7puo by Molmil
Structure of a fused 4-OT variant engineered for asymmetric Michael addition reactions
Descriptor: 2-hydroxymuconate tautomerase,Chains: A,B,C,D,E,F,2-hydroxymuconate tautomerase, CHLORIDE ION, GLYCEROL
Authors:Rozeboom, H.J, Thunnissen, A.M.W.H, Poelarends, G.J.
Deposit date:2021-09-30
Release date:2022-01-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Gene Fusion and Directed Evolution to Break Structural Symmetry and Boost Catalysis by an Oligomeric C-C Bond-Forming Enzyme.
Angew.Chem.Int.Ed.Engl., 61, 2022
6R1L
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BU of 6r1l by Molmil
Crystal structure of LmrR with bound copper phenanthroline
Descriptor: 1,10-PHENANTHROLINE, COPPER (II) ION, Transcriptional regulator, ...
Authors:Reddem, R, Thunnissen, A.M.W.H.
Deposit date:2019-03-14
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.095 Å)
Cite:Cofactor Binding Dynamics Influence the Catalytic Activity and Selectivity of an Artificial Metalloenzyme.
Acs Catalysis, 10, 2020
7B4I
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BU of 7b4i by Molmil
Thermostable omega transaminase PjTA-R6 variant W58G engineered for asymmetric synthesis of enantiopure bulky amines
Descriptor: Aspartate aminotransferase family protein, PYRIDOXAL-5'-PHOSPHATE, SUCCINIC ACID
Authors:Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B.
Deposit date:2020-12-02
Release date:2021-09-01
Last modified:2021-09-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Computational Redesign of an omega-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines.
Acs Catalysis, 11, 2021
7B4J
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BU of 7b4j by Molmil
Thermostable omega transaminase PjTA-R6 variant W58M/F86L/R417L engineered for asymmetric synthesis of enantiopure bulky amines
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase family protein, SUCCINIC ACID
Authors:Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B.
Deposit date:2020-12-02
Release date:2021-09-01
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Computational Redesign of an omega-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines.
Acs Catalysis, 11, 2021
1OXT
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BU of 1oxt by Molmil
Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
Descriptor: ABC transporter, ATP binding protein
Authors:Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M.
Deposit date:2003-04-03
Release date:2003-06-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations
J.Mol.Biol., 330, 2003
1OXS
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BU of 1oxs by Molmil
Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
Descriptor: ABC transporter, ATP binding protein, IODIDE ION
Authors:Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M.
Deposit date:2003-04-03
Release date:2003-06-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations
J.Mol.Biol., 330, 2003
1OXV
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BU of 1oxv by Molmil
Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
Descriptor: ABC transporter, ATP binding protein, IODIDE ION, ...
Authors:Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M.
Deposit date:2003-04-03
Release date:2003-06-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations
J.Mol.Biol., 330, 2003
1OXU
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BU of 1oxu by Molmil
Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
Descriptor: ABC transporter, ATP binding protein, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M.
Deposit date:2003-04-03
Release date:2003-06-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations
J.Mol.Biol., 330, 2003
5MDX
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BU of 5mdx by Molmil
Cryo-EM structure of the PSII supercomplex from Arabidopsis thaliana
Descriptor: CHLOROPHYLL A, CHLOROPHYLL B, Chlorophyll a-b binding protein 1, ...
Authors:van Bezouwen, L.S, Caffarri, S, Kale, R.S, Kouril, R, Thunnissen, A.M.W.H, Oostergetel, G.T, Boekema, E.J.
Deposit date:2016-11-13
Release date:2017-06-21
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Subunit and chlorophyll organization of the plant photosystem II supercomplex.
Nat Plants, 3, 2017
5OFQ
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BU of 5ofq by Molmil
Crystal structure of substrate-free CYP109A2 from Bacillus megaterium
Descriptor: Cytochrome P450, PENTAETHYLENE GLYCOL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2017-07-11
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Biochemical and structural characterization of CYP109A2, a vitamin D3 25-hydroxylase from Bacillus megaterium.
FEBS J., 284, 2017
9GTV
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BU of 9gtv by Molmil
Crystal structure of RamR with Tyr59 replaced with para-boronophenylalanine (boronate form)
Descriptor: Transcriptional regulator RamR
Authors:Longwitz, L, Brouwer, B, Thunnissen, A.M.W.H, Roelfes, G.
Deposit date:2024-09-18
Release date:2024-12-25
Last modified:2025-01-08
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Boron Designer Enzyme with a Hybrid Catalytic Dyad.
Acs Catalysis, 14, 2024
1IIG
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BU of 1iig by Molmil
STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHONOPROPIONATE
Descriptor: 3-PHOSPHONOPROPANOIC ACID, TRIOSEPHOSPHATE ISOMERASE
Authors:Noble, M.E, Wierenga, R.K, Lambeir, A.M, Opperdoes, F.R, Thunnissen, A.M, Kalk, K.H, Groendijk, H, Hol, W.G.J.
Deposit date:2001-04-23
Release date:2001-05-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Proteins, 10, 1991

235183

數據於2025-04-23公開中

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