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PDB: 45 results

2IM0
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BU of 2im0 by Molmil
Crystal structure of poliovirus polymerase complexed with CTP and Mg2+
Descriptor: ACETIC ACID, CYTIDINE-5'-TRIPHOSPHATE, SODIUM ION, ...
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2006-10-03
Release date:2006-12-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
2IM2
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BU of 2im2 by Molmil
Crystal structure of poliovirus polymerase complexed with UTP and Mg2+
Descriptor: ACETIC ACID, SODIUM ION, URIDINE 5'-TRIPHOSPHATE, ...
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2006-10-03
Release date:2006-12-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
3EVF
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BU of 3evf by Molmil
Crystal structure of Me7-GpppA complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine
Descriptor: P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A, Geiss, B.J, Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVE
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BU of 3eve by Molmil
Crystal structure of GpppA complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine
Descriptor: GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVC
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BU of 3evc by Molmil
Crystal structure of GTP complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A, Geiss, B.J, Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVA
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BU of 3eva by Molmil
Crystal structure of yellow fever virus methyltransferase complexed with S-adenosyl-L-homocysteine
Descriptor: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A, Geiss, B.J, Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVB
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BU of 3evb by Molmil
Crystal structure of yellow fever virus methyltransferase complexed with S-adenosyl-L-homocysteine
Descriptor: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A, Geiss, B.J, Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVD
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BU of 3evd by Molmil
Crystal structure of GTP complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thompson, A.A, Geiss, B.J, Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVG
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BU of 3evg by Molmil
Crystal structure of Dengue-2 virus methyltransferase complexed with S-adenosyl-L-homocysteine
Descriptor: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION
Authors:Thompson, A.A, Geiss, B.J, Peersen, O.B.
Deposit date:2008-10-13
Release date:2009-01-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
8VXE
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BU of 8vxe by Molmil
Structure of p38 alpha (Mitogen-activated protein kinase 14) complexed with inhibitor 6
Descriptor: (4M)-4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine, Mitogen-activated protein kinase 14
Authors:Blaesse, M, Steinbacher, S, Shaffer, P.L, Sharma, S, Thompson, A.A.
Deposit date:2024-02-04
Release date:2024-05-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure-Based Optimization of Selective and Brain Penetrant CK1 delta Inhibitors for the Treatment of Circadian Disruptions.
Acs Med.Chem.Lett., 15, 2024
5DHH
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BU of 5dhh by Molmil
The crystal structure of nociceptin/orphanin FQ peptide receptor (NOP) in complex with SB-612111 (PSI Community Target)
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (5S,7S)-7-{[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl}-1-methyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol, OLEIC ACID, ...
Authors:Miller, R.L, Thompson, A.A, Trapella, C, Guerrini, R, Malfacini, D, Patel, N, Han, G.W, Cherezov, V, Calo, G, Katritch, V, Stevens, R.C, GPCR Network (GPCR)
Deposit date:2015-08-31
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor.
Structure, 23, 2015
5DHG
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BU of 5dhg by Molmil
The crystal structure of nociceptin/orphanin FQ peptide receptor (NOP) in complex with C-35 (PSI Community Target)
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-benzyl-N-{3-[4-(2,6-dichlorophenyl)piperidin-1-yl]propyl}-D-prolinamide, OLEIC ACID, ...
Authors:Miller, R.L, Thompson, A.A, Trapella, C, Guerrini, R, Malfacini, D, Patel, N, Han, G.W, Cherezov, V, Calo, G, Katritch, V, Stevens, R.C, GPCR Network (GPCR)
Deposit date:2015-08-30
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor.
Structure, 23, 2015
4EIY
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BU of 4eiy by Molmil
Crystal structure of the chimeric protein of A2aAR-BRIL in complex with ZM241385 at 1.8A resolution
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, ...
Authors:Liu, W, Chun, E, Thompson, A.A, Chubukov, P, Xu, F, Katritch, V, Han, G.W, Heitman, L.H, Ijzerman, A.P, Cherezov, V, Stevens, R.C, GPCR Network (GPCR)
Deposit date:2012-04-06
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for allosteric regulation of GPCRs by sodium ions.
Science, 337, 2012
4DJH
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BU of 4djh by Molmil
Structure of the human kappa opioid receptor in complex with JDTic
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, CITRIC ACID, ...
Authors:Wu, H, Wacker, D, Katritch, V, Mileni, M, Han, G.W, Vardy, E, Liu, W, Thompson, A.A, Huang, X.P, Carroll, F.I, Mascarella, S.W, Westkaemper, R.B, Mosier, P.D, Roth, B.L, Cherezov, V, Stevens, R.C, GPCR Network (GPCR)
Deposit date:2012-02-01
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:tructure of the human kappa-opioid receptor in complex with JDTic
Nature, 485, 2012
4N6H
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BU of 4n6h by Molmil
1.8 A Structure of the human delta opioid 7TM receptor (PSI Community Target)
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol, L(+)-TARTARIC ACID, ...
Authors:Fenalti, G, Giguere, P.M, Katritch, V, Huang, X.-P, Thompson, A.A, Han, G.W, Cherezov, V, Roth, B.L, Stevens, R.C, GPCR Network (GPCR)
Deposit date:2013-10-12
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular control of delta-opioid receptor signalling.
Nature, 506, 2014
8E8O
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BU of 8e8o by Molmil
Cryo-EM structure of human ME3 in the presence of citrate
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent malic enzyme, mitochondrial
Authors:Yu, X, Grell, T.A.J, Shaffer, P.L, Steele, R, Sharma, S, Thompson, A.A, Tresadern, G, Ortiz-Meoz, R.F, Mason, M, Gomez-Tamayo, J.C, Riley, D, Wagner, M.V, Wadia, J.
Deposit date:2022-08-25
Release date:2023-02-08
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer.
Heliyon, 8, 2022
8E76
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BU of 8e76 by Molmil
Cryo-EM structure of Apo form ME3
Descriptor: NADP-dependent malic enzyme, mitochondrial
Authors:Yu, X, Grell, T.A.J, Shaffer, P.L, Steele, R, Sharma, S, Thompson, A.A, Tresadern, G, Ortiz-Meoz, R.F, Mason, M, Gomez-Tamayo, J.C, Riley, D, Wagner, M.V, Wadia, J.
Deposit date:2022-08-23
Release date:2023-02-08
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer.
Heliyon, 8, 2022
8E78
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BU of 8e78 by Molmil
Cryo-EM structure of human ME3 in the presence of citrate
Descriptor: NADP-dependent malic enzyme, mitochondrial
Authors:Yu, X, Grell, T.A.J, Shaffer, P.L, Steele, R, Sharma, S, Thompson, A.A, Tresadern, G, Ortiz-Meoz, R.F, Mason, M, Gomez-Tamayo, J.C, Riley, D, Wagner, M.V, Wadia, J.
Deposit date:2022-08-23
Release date:2023-02-08
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer.
Heliyon, 8, 2022
8EYO
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BU of 8eyo by Molmil
Crystal Structure of Human Mitochondrial NADP+ Malic Enzyme 3 with NADP bound
Descriptor: CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent malic enzyme, ...
Authors:Shaffer, P.L, Grell, T.A.J, Mason, M, Thompson, A.A, Riley, D, Wagner, M.V, Steele, R, Ortiz-Meoz, R, Wadia, J, Sharma, S, Yu, X.
Deposit date:2022-10-28
Release date:2023-02-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer.
Heliyon, 8, 2022
8EYN
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BU of 8eyn by Molmil
Crystal Structure of Human Mitochondrial NADP+ Malic Enzyme 3 in Apo Form
Descriptor: CITRIC ACID, NADP-dependent malic enzyme, mitochondrial
Authors:Shaffer, P.L, Grell, T.A.J, Mason, M, Thompson, A.A, Riley, D, Wagner, M.V, Steele, R, Ortiz-Meoz, R, Wadia, J, Sharma, S, Yu, X.
Deposit date:2022-10-28
Release date:2023-02-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer.
Heliyon, 8, 2022
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222036

數據於2024-07-03公開中

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