4EIY
Crystal structure of the chimeric protein of A2aAR-BRIL in complex with ZM241385 at 1.8A resolution
Summary for 4EIY
Entry DOI | 10.2210/pdb4eiy/pdb |
Related | 3eml |
Descriptor | Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ... (9 entities in total) |
Functional Keywords | novel protein engineering, gpcr network, psi-biology, structural genomics, membrane protein, gpcr |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P29274 |
Total number of polymer chains | 1 |
Total formula weight | 58721.97 |
Authors | Liu, W.,Chun, E.,Thompson, A.A.,Chubukov, P.,Xu, F.,Katritch, V.,Han, G.W.,Heitman, L.H.,Ijzerman, A.P.,Cherezov, V.,Stevens, R.C.,GPCR Network (GPCR) (deposition date: 2012-04-06, release date: 2012-07-25, Last modification date: 2023-09-13) |
Primary citation | Liu, W.,Chun, E.,Thompson, A.A.,Chubukov, P.,Xu, F.,Katritch, V.,Han, G.W.,Roth, C.B.,Heitman, L.H.,IJzerman, A.P.,Cherezov, V.,Stevens, R.C. Structural basis for allosteric regulation of GPCRs by sodium ions. Science, 337:232-236, 2012 Cited by PubMed: 22798613DOI: 10.1126/science.1219218 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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