3EML
The 2.6 A Crystal Structure of a Human A2A Adenosine Receptor bound to ZM241385.
Summary for 3EML
Entry DOI | 10.2210/pdb3eml/pdb |
Descriptor | Human Adenosine A2A receptor/T4 lysozyme chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, STEARIC ACID, ... (5 entities in total) |
Functional Keywords | adenosine, caffeine, gpcr, membrane protein, receptor, lcp, mesophase, structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, gpcr network |
Biological source | Homo sapiens More |
Cellular location | Cell membrane; Multi-pass membrane protein: P29274 |
Total number of polymer chains | 1 |
Total formula weight | 57171.93 |
Authors | Jaakola, V.-P.,Griffith, M.T.,Hanson, M.A.,Cherezov, V.,Chien, E.Y.T.,Lane, J.R.,Ijzerman, A.P.,Stevens, R.C.,Accelerated Technologies Center for Gene to 3D Structure (ATCG3D),GPCR Network (GPCR) (deposition date: 2008-09-24, release date: 2008-10-14, Last modification date: 2023-09-06) |
Primary citation | Jaakola, V.P.,Griffith, M.T.,Hanson, M.A.,Cherezov, V.,Chien, E.Y.,Lane, J.R.,Ijzerman, A.P.,Stevens, R.C. The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist. Science, 322:1211-1217, 2008 Cited by PubMed: 18832607DOI: 10.1126/science.1164772 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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