Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5DHH

The crystal structure of nociceptin/orphanin FQ peptide receptor (NOP) in complex with SB-612111 (PSI Community Target)

Summary for 5DHH
Entry DOI10.2210/pdb5dhh/pdb
Related4EA3
DescriptorSoluble cytochrome b562,Nociceptin receptor, OLEIC ACID, (5S,7S)-7-{[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl}-1-methyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol, ... (4 entities in total)
Functional Keywordsnociceptin/orphanin fq peptide receptor, nop, orl-1, n/ofq, opioid receptor, g protein-coupled receptor, gpcr, membrane protein, lipidic cubic phase, bret, receptor-ligand conformational pair, structural genomics, psi-biology, gpcr network, signaling protein, psicnt-127
Biological sourceEscherichia coli
More
Cellular locationCell membrane; Multi-pass membrane protein: P41146
Total number of polymer chains2
Total formula weight96563.31
Authors
Miller, R.L.,Thompson, A.A.,Trapella, C.,Guerrini, R.,Malfacini, D.,Patel, N.,Han, G.W.,Cherezov, V.,Calo, G.,Katritch, V.,Stevens, R.C.,GPCR Network (GPCR) (deposition date: 2015-08-31, release date: 2015-10-21, Last modification date: 2023-09-27)
Primary citationMiller, R.L.,Thompson, A.A.,Trapella, C.,Guerrini, R.,Malfacini, D.,Patel, N.,Han, G.W.,Cherezov, V.,Calo, G.,Katritch, V.,Stevens, R.C.
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor.
Structure, 23:2291-2299, 2015
Cited by
PubMed: 26526853
DOI: 10.1016/j.str.2015.07.024
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.004 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon