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PDB: 214 results

4OE6
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Crystal Structure of Yeast ALDH4A1
Descriptor: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
Authors:Tanner, J.J.
Deposit date:2014-01-11
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Structural Studies of Yeast Delta (1)-Pyrroline-5-carboxylate Dehydrogenase (ALDH4A1): Active Site Flexibility and Oligomeric State.
Biochemistry, 53, 2014
4OE4
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Crystal Structure of Yeast ALDH4A1 Complexed with NAD+
Descriptor: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Tanner, J.J.
Deposit date:2014-01-11
Release date:2014-02-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.168 Å)
Cite:Structural Studies of Yeast Delta (1)-Pyrroline-5-carboxylate Dehydrogenase (ALDH4A1): Active Site Flexibility and Oligomeric State.
Biochemistry, 53, 2014
4OE5
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Structure of Human ALDH4A1 Crystallized in Space Group P21
Descriptor: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, MAGNESIUM ION, ...
Authors:Tanner, J.J.
Deposit date:2014-01-11
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Studies of Yeast Delta (1)-Pyrroline-5-carboxylate Dehydrogenase (ALDH4A1): Active Site Flexibility and Oligomeric State.
Biochemistry, 53, 2014
6X0K
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Structure of dithionite-reduced SidA ornithine hydroxylase with the FAD "in" and complexed with L-ornithine
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-ornithine, L-ornithine N(5)-monooxygenase
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-05-15
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.231 Å)
Cite:Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
6WPU
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BU of 6wpu by Molmil
Structure of S-allyl-L-cysteine S-oxygenase from Allium sativum
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Flavin-containing monooxygenase, SULFATE ION
Authors:Tanner, J.J, Campbell, A.C, Schuermann, J.P.
Deposit date:2020-04-27
Release date:2020-06-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.084 Å)
Cite:Structure and function of a flavin-dependent S-monooxygenase from garlic (Allium sativum).
J.Biol.Chem., 295, 2020
6X0H
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Structure of oxidized SidA ornithine hydroxylase with the FAD in the "out" conformation
Descriptor: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-05-15
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.087 Å)
Cite:Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
6X0J
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Structure of reduced SidA ornithine hydroxylase with the FAD "in" and complexed with NADP and L-ornithine
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-ornithine, L-ornithine N(5)-monooxygenase, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-05-15
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.335 Å)
Cite:Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
6X0I
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Structure of oxidized SidA ornithine hydroxylase with the FAD "in" and complexed with NADP
Descriptor: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-05-15
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
6X9B
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Structure of proline utilization A with cis-4-hydroxy-D-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
Descriptor: (4R)-4-hydroxy-D-proline, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6X9C
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Structure of proline utilization A with L-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6XOZ
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Structure of human PYCR1 complexed with L-tetrahydro-2-furoic acid
Descriptor: CHLORIDE ION, Pyrroline-5-carboxylate reductase 1, mitochondrial, ...
Authors:Tanner, J.J, Christensen, E.M.
Deposit date:2020-07-07
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J.Biol.Chem., 295, 2020
6X99
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Structure of proline utilization A with D-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
Descriptor: Bifunctional protein PutA, D-PROLINE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
1P7K
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BU of 1p7k by Molmil
Crystal structure of an anti-ssDNA antigen-binding fragment (Fab) bound to 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid (HEPES)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Schuermann, J.P, Henzl, M.T, Deutscher, S.L, Tanner, J.J.
Deposit date:2003-05-02
Release date:2004-05-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of an anti-DNA fab complexed with a non-DNA ligand provides insights into cross-reactivity and molecular mimicry.
Proteins, 57, 2004
2G82
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BU of 2g82 by Molmil
High Resolution Structures of Thermus aquaticus Glyceraldehyde-3-Phosphate Dehydrogenase: Role of 220's Loop Motion in Catalysis
Descriptor: GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, ISOPROPYL ALCOHOL, ...
Authors:Jenkins, J.L, Buencamino, R, Tanner, J.J.
Deposit date:2006-03-01
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:High Resolution Structures of Thermus aquaticus Glyceraldehyde-3-Phosphate Dehydrogenase: Role of 220's Loop Motion in Catalysis
To be Published
4ZUK
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BU of 4zuk by Molmil
Structure ALDH7A1 complexed with NAD+
Descriptor: Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TETRAETHYLENE GLYCOL
Authors:Luo, M, Tanner, J.J.
Deposit date:2015-05-16
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
Biochemistry, 54, 2015
4ZUL
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BU of 4zul by Molmil
Structure ALDH7A1 complexed with alpha-aminoadipate
Descriptor: 2-AMINOHEXANEDIOIC ACID, Alpha-aminoadipic semialdehyde dehydrogenase, TETRAETHYLENE GLYCOL, ...
Authors:Luo, M, Tanner, J.J.
Deposit date:2015-05-16
Release date:2015-08-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
Biochemistry, 54, 2015
6UFP
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BU of 6ufp by Molmil
Structure of proline utilization A with the FAD covalently modified by L-thiazolidine-2-carboxylate and three cysteines (Cys46, Cys470, Cys638) modified to S,S-(2-HYDROXYETHYL)THIOCYSTEINE
Descriptor: (2S)-1,3-thiazolidine-2-carboxylic acid, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Campbell, A.C, Tanner, J.J.
Deposit date:2019-09-24
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.737 Å)
Cite:Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate.
Acs Chem.Biol., 15, 2020
6C7S
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BU of 6c7s by Molmil
Structure of Rifampicin Monooxygenase with Product Bound
Descriptor: (1E,3S,4R,5S,6R,7R,8R,9S,10S,11E,13E)-15-amino-1-{[(2S)-5,7-dihydroxy-2,4-dimethyl-8-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-1,6,9-trioxo-1,2,6,9-tetrahydronaphtho[2,1-b]furan-2-yl]oxy}-7,9-dihydroxy-3-methoxy-4,6,8,10,14-pentamethyl-15-oxopentadeca-1,11,13-trien-5-yl acetate, 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Liu, L.-K, Tanner, J.J.
Deposit date:2018-01-23
Release date:2018-04-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Evidence for Rifampicin Monooxygenase Inactivating Rifampicin by Cleaving Its Ansa-Bridge.
Biochemistry, 57, 2018
6D96
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Structure of influenza neuraminidase from strain A/BrevigMission/1/1918(H1N1) expressed in HEK-293E cells
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Campbell, A.C, Krause, K.L, Tanner, J.J.
Deposit date:2018-04-27
Release date:2019-05-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Optimisation of neuraminidase expression by HEK-293E cells for use in structural biology
To Be Published
4X0U
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Structure ALDH7A1 inactivated by 4-diethylaminobenzaldehyde
Descriptor: 4-(diethylamino)benzaldehyde, Alpha-aminoadipic semialdehyde dehydrogenase, MAGNESIUM ION
Authors:Luo, M, Tanner, J.J.
Deposit date:2014-11-23
Release date:2015-01-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Diethylaminobenzaldehyde Is a Covalent, Irreversible Inactivator of ALDH7A1.
Acs Chem.Biol., 10, 2015
4X0T
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Structure ALDH7A1 inactivated by 4-diethylaminobenzaldehyde and complexed with NAD+
Descriptor: 4-(diethylamino)benzaldehyde, Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Luo, M, Tanner, J.J.
Deposit date:2014-11-23
Release date:2015-01-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Diethylaminobenzaldehyde Is a Covalent, Irreversible Inactivator of ALDH7A1.
Acs Chem.Biol., 10, 2015
4H6Q
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BU of 4h6q by Molmil
Structure of oxidized Deinococcus radiodurans proline dehydrogenase complexed with L-tetrahydrofuroic acid
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Proline dehydrogenase, ...
Authors:Min, L, Tanner, J.J.
Deposit date:2012-09-19
Release date:2012-11-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.359 Å)
Cite:Crystal structures and kinetics of monofunctional proline dehydrogenase provide insight into substrate recognition and conformational changes associated with flavin reduction and product release.
Biochemistry, 51, 2012
4H6R
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Structure of reduced Deinococcus radiodurans proline dehydrogenase
Descriptor: ACETATE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Proline dehydrogenase
Authors:Min, L, Tanner, J.J.
Deposit date:2012-09-19
Release date:2012-11-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures and kinetics of monofunctional proline dehydrogenase provide insight into substrate recognition and conformational changes associated with flavin reduction and product release.
Biochemistry, 51, 2012
4K57
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BU of 4k57 by Molmil
Structure of Thermus thermophilus 1-pyrroline-5-carboxylate dehydrogenase R100A mutant
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, Delta-1-pyrroline-5-carboxylate dehydrogenase
Authors:Luo, M.L, Singh, R.K, Tanner, J.J.
Deposit date:2013-04-13
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.537 Å)
Cite:Structural determinants of oligomerization of delta (1)-pyrroline-5-carboxylate dehydrogenase: identification of a hexamerization hot spot.
J.Mol.Biol., 425, 2013
8DKG
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BU of 8dkg by Molmil
Structure of PYCR1 Thr171Met variant complexed with NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Isoform 3 of Pyrroline-5-carboxylate reductase 1, mitochondrial, ...
Authors:Meeks, K.R, Tanner, J.J.
Deposit date:2022-07-05
Release date:2023-02-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Functional Impact of a Cancer-Related Variant in Human Delta 1 -Pyrroline-5-Carboxylate Reductase 1.
Acs Omega, 8, 2023

222624

數據於2024-07-17公開中

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