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PDB: 42 results

6UKS
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BU of 6uks by Molmil
ATPgammaS bound mBcs1
Descriptor: MAGNESIUM ION, Mitochondrial chaperone BCS1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Tang, W.K, Borgnia, M.J, Hsu, A.L, Xia, D.
Deposit date:2019-10-05
Release date:2020-02-05
Last modified:2020-02-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein.
Nat.Struct.Mol.Biol., 27, 2020
6U1Y
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BU of 6u1y by Molmil
bcs1 AAA domain
Descriptor: MAGNESIUM ION, Mitochondrial chaperone BCS1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Tang, W.K, Xia, D.
Deposit date:2019-08-17
Release date:2020-02-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein.
Nat.Struct.Mol.Biol., 27, 2020
6UKP
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BU of 6ukp by Molmil
Apo mBcs1
Descriptor: Mitochondrial chaperone BCS1
Authors:Tang, W.K, Borgnia, M.J, Hsu, A.L, Xia, D.
Deposit date:2019-10-05
Release date:2020-02-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein.
Nat.Struct.Mol.Biol., 27, 2020
8DCE
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BU of 8dce by Molmil
SARS-CoV-2 Receptor-Binding Domain SPEEDesign Immunogen 1 Bound to C144 scFv
Descriptor: C144 scFv, Spike protein S1
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-06-16
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response.
Sci Adv, 8, 2022
5DYI
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BU of 5dyi by Molmil
Structure of p97 N-D1 wild-type in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Tang, W.K, Xia, D.
Deposit date:2015-09-24
Release date:2016-02-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:Role of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain.
Sci Rep, 6, 2016
7U9E
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BU of 7u9e by Molmil
Pfs230 D1 domain in complex with 230AL-26
Descriptor: 230AL-26, Gametocyte surface protein P230, LMIV230-01
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-10
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
5DYG
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BU of 5dyg by Molmil
Structure of p97 N-D1 L198W mutant in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Tang, W.K, Xia, D.
Deposit date:2015-09-24
Release date:2016-02-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Role of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain.
Sci Rep, 6, 2016
5KIW
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BU of 5kiw by Molmil
p97 ND1-L198W in complex with VIMP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Selenoprotein S, ...
Authors:Tang, W.K, Xia, D.
Deposit date:2016-06-17
Release date:2018-03-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Structural basis for nucleotide-modulated p97 association with the ER membrane.
Cell Discov, 3, 2017
5KIY
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BU of 5kiy by Molmil
p97 ND1-A232E in complex with VIMP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Selenoprotein S, ...
Authors:Tang, W.K, Xia, D.
Deposit date:2016-06-17
Release date:2017-12-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural basis for nucleotide-modulated p97 association with the ER membrane.
Cell Discov, 3, 2017
5KIU
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BU of 5kiu by Molmil
VCP-interacting membrane protein (VIMP)
Descriptor: Selenoprotein S
Authors:Tang, W.K, Xia, D.
Deposit date:2016-06-17
Release date:2017-12-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for nucleotide-modulated p97 association with the ER membrane.
Cell Discov, 3, 2017
2JG7
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BU of 2jg7 by Molmil
Crystal structure of Seabream Antiquitin and Elucidation of its substrate specificity
Descriptor: ANTIQUITIN, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Tang, W.K, Wong, K.B, Cha, S.S, Lee, H.S, Cheng, C.H.K, Fong, W.P.
Deposit date:2007-02-09
Release date:2008-05-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:The Crystal Structure of Seabream Antiquitin Reveals the Structural Basis of its Substrate Specificity.
FEBS Lett., 582, 2008
7UA8
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BU of 7ua8 by Molmil
Pfs230 D1 domain in complex with 230AL-20
Descriptor: 230Al-20, Gametocyte surface protein P230
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-11
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UA2
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BU of 7ua2 by Molmil
Pfs230 D1 domain in complex with 230AL-18
Descriptor: 230AL-18, Gametocyte surface protein P230, LMIV230-01
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-11
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7U9W
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BU of 7u9w by Molmil
Pfs230 D1 domain in complex with 230AS-88
Descriptor: 230AS-88, Gametocyte surface protein P230
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-11
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UFW
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BU of 7ufw by Molmil
Pfs230 D1D2 in complex with LMIV230-01
Descriptor: Gametocyte surface protein P230, LMIV230-01
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-23
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UCQ
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BU of 7ucq by Molmil
Pfs230 D1 domain in complex with 230AS-18
Descriptor: 230AS-18, Gametocyte surface protein P230
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-17
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UI1
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BU of 7ui1 by Molmil
Pfs230 D1D2 domain in complex with 230AL-37
Descriptor: 230AL-37, Gametocyte surface protein P230, SULFATE ION
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-28
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UC8
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BU of 7uc8 by Molmil
Pfs230 D1 domain in complex with 230AS-73
Descriptor: 230AS-73, Gametocyte surface protein P230, SODIUM ION
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-16
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UBS
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BU of 7ubs by Molmil
Pfs230 D1 domain in complex with 230AS-26
Descriptor: 230AS-26, Gametocyte surface protein P230
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-15
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
6MCK
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BU of 6mck by Molmil
p97 D1D2 with CB5083 bound
Descriptor: 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, Transitional endoplasmic reticulum ATPase
Authors:Xia, D, Tang, W.K.
Deposit date:2018-08-31
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.77 Å)
Cite:Structural Basis of p97 Inhibition by the Site-Selective Anticancer Compound CB-5083.
Mol. Pharmacol., 95, 2019
8DFG
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BU of 8dfg by Molmil
Crystal structure of potently neutralizing human monoclonal antibody 42D6 Fab in complex with MSP1-19
Descriptor: 42D6 Fab Heavy Chain, 42D6 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFH
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BU of 8dfh by Molmil
Crystal structure of non-neutralizing / interfering human monoclonal antibody 42C3 Fab in complex with MSP1-19
Descriptor: 42C3 Fab Heavy Chain, 42C3 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFI
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BU of 8dfi by Molmil
Crystal structure of moderately neutralizing / interfering human monoclonal antibody 42C11 Fab in complex with MSP1-19
Descriptor: 42C11 Fab Heavy Chain, 42C11 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8E1Z
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BU of 8e1z by Molmil
Crystal structure of Plasmodium falciparum ookinete surface antigen Pfs28
Descriptor: CHLORIDE ION, Ookinete surface protein Pfs28, SULFATE ION
Authors:Shukla, N, Tang, W.K, Tolia, N.H.
Deposit date:2022-08-12
Release date:2022-11-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of Plasmodium falciparum ookinete surface antigen Pfs28 relevant for malaria vaccine design.
Sci Rep, 12, 2022
8EZL
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BU of 8ezl by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-50
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, ...
Authors:Shukla, N, Tang, W.K, Tolia, N.H.
Deposit date:2022-11-01
Release date:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023

 

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